한국 홍삼과 백삼의 조산성 다당체 성분과 수용성 추출물, 그리고 ginsenoside 성분이 암독소 호르몬-L에 의해 유도된 지방 분해를 저해하는 효과를 검토하고자 본 연구를 수행하였다. 지방분해 빛 식욕억제 인자로 알려진 암독소 호르몬-L은 sarcoma-180을 접종한 mouse의 복수액으로 부터 부분정제하여 사용하였다. 한국 홍삼과 백삼으로부터 정제하여 얻은 조산성 다당체 각 분획의 성분은 10 ㎍/㎖농도 이상에서 암독소 호르몬-L이 유도하는 지방 분해에 억제효과가 있었고, 이들 중 PG_1과 PG_4에서 지방 분해 저해 활성이 가장 높았으며, 이를 더 정제한 결과 PG_4-3분획에서 활성이 가장 높았다. 고려인삼중 백삼과 홍삼의 각 4, 5, 6 년근별로 얻은 수용성 추출물의 암독소 호르몬-L의 지방분해 억제에 미치는 영향을 검토한 결과 억제율은 1, 000 ㎍/㎖ 농도에서 백삼 4, 5 및 6년근이 각각 56.3, 59.7 및 59.4% 였고, 홍삼은 각각 78.6, 79.1 및 82.5%로 백삼보다 홍삼의 억제율이 높았다. 인삼 시료 g 당 총저해활성(unit/g)은 백삼의 경우 100 ㎍/㎖농도에서는 4년근이, 1, 000 ㎍/㎖농도에서는 5년근에서 가장 높았으나, 홍삼의 경우 다같이 6년근에서 가장 높았다. 또한 ginsenoside 성분의 경우 지방 분해 억제율과 총저해활성이 모두 Rb_2에서 가장 높았다

The survey was conducted for the period from 25th to 29th July, 1990. The survey area were selected the mountain area in Kang Won Province. Intake of foods and nutrients of all members in the households surveyed by means of questionnaire was computed based on number of meals a day. On the other hand, daily intake of nutrients by an individual was calculated by sex, age and type of work based on the conversion rate of RDA (Korean Recommended Dietary Allowances for Adult) . 1. Status of food intake. The average food intake per person per day in surveyed area was 1103.49g. The total intake of food was consisted of 44.17% grains, 23.31% vegetables, 10.66% fruits, respectively. These findings led us to the conclusion that people in the surveyed area depended heavily on plant foods. 2. Status of nutrient intake. 1) The average intake of Calorie was 2567.54㎈ per day, which was slightly higher than 2500㎈ of RDA. 2) The average intake of protein was 82.92g per day, which was higher than 70 g of RDA. Though the quantity was above the RDA, it was largely from plant foods. 3) The average intake of calcium was 383.93㎎ per day, which was much lower than 600㎎ of RDA. 4) The average intake of iron was 11.88㎎ per day, which was nearly the same quantity as 10㎎ of RDA . 5) Intake of vitamin group were high among the inhabitants than recommended by RDA 3. The Kinds of food intake. The kinds of food intake in surveyed area were totally 66 different kinds. 4. Economic status. As for the education level, almost of the food handlers finished the primary school and the average monthly income was ￦364, 600 in surveyed area. Households used gas(100%) for fuel.