This study is carried out to evaluate the commercial feasibility of the room temperature and thermal polymerization method as a lens manufacturing method. All samples are found to be transparent after polymerization, thereby indicating that their physical and surface properties are suitable for hydrogel ophthalmic lenses. The optical and physical properties of the lenses are compared. The water content of the samples that are prepared via a room temperature polymerization process decreases with the addition of MMA as compared to the water content of the samples that are prepared via thermal polymerization. When MMA and DMA are used as an additive for improving functionality, the wettability of the lenses increases. By measuring the AFM, the surface roughness is shown to improve more than MMA and DMA. Therefore, it is judged to be an appropriate process for manufacturing hydrogel lenses with high functionality.

Purpose: This research was conducted to produce the functional hydrogel ophthalmic lens containing nanoparticles. Methods: Carbon nanoparticles and PEGMEMA were used as additives for the basic combination containing HEMA, MA, and MMA, and the material was copolymerized with EGDMA as the cross-linking agent and AIBN as the initiator. The hydrogel lens was produced by a cast-mold method, and the materials were thermally polymerized at 100° C for an hour. The polymerized lens sample was hydrated in a 0.9% saline for 24 hours before the optical and physical characteristics of the lens were measured. Results: The refractive index, water content, contact angle, light transmittance, and tensile strength were measured to evaluate the physical and optical characteristics of the hydrogel lens. The results showed that the refractive index, water content, contact angle, UV-B light transmittance, UV-A light transmittance, visible light transmittance and tensile strength of the hydrogel lens polymer was 1.4019~1.4281, 43.05~51.18%, 31.95~68.61°, 21.69~58.11%, 35.59~84.26%, 45.85~88.06% and 0.0657~0.1649kgf, respectively. It showed an increase of refractive index and tensile strength while decreased in contact angle and light transmittance. Conclusions: This material can be used for ophthalmic lenses with high performance of wettability, ultraviolet ray blocking effect, and tensile strength. Furthermore, the visible light transmissibility was significantly increased at PEG 10%.

Purpose : UV-block effect of soft contact lens polymerized and with 2,4-dihydroxybenzophenone in the basic hydrogel contact lens material was evaluated. and also the influence of sterilization condition on change of optical properties was analyzed. Methods: 2,4-dihydroxybenzophenone as additive with 2-hydroxyethyl methacrylate and the initiator AIBN were used for thermal copolymerization. The mixture was heated at 100 ℃ for 50 mins to produce the hydrogel contact lens. and they are heated at 115 ℃ for 3 hour for sterilization. Results: The optical properties of produced contact lens including 2,4-dihydroxybenzophenone showed that the UV-A transmittance was 28~36% and the UV-B transmittance was 10~18%. and Also, in case of sterilization situation, the results showed that the UV-A transmittance was 5~17% and the UV-B transmittance was 4~16%, respectively. Conclusions: After sterilization of produced contact lens, UV-block effect of soft contact lens including benzophenone group was increased.

Purpose : Recently, the eye disease associated with ultraviolet radiation were reported. In this study, the UV-block hydrophilic soft contact lens using 2-ethylhexyl trans-4-methoxy-cinnamate were manufactured and the optical properties of copolymerized materials were measured. Methods: The basic hydrophilic soft contact lens material with addition of Dhb(2,4-dihydroxy benzophenone) 0.5% ~ 1.0%, Thb(2,4,4-trihydroxy benzophenone) 0.5% ~ 1.0% and Hmb(2-hydroxy-4-methoxy benzophenone) 0.5% ~ 1.0% respectively were polymerized and the hydrophilic soft contact lens were manufactured by cast mould method. The lenses were stored in a 0.9% NaCl normal saline for analysis. Results: In the measurement of DHB samples, the optical transmittance showed the UV-B transmittance of 2.1 ~ 4.3%, UV-A transmittance of 19.0 ~ 27.2% and visible transmittance 88.8 ~ 90.1%. And also, in the case of THB samples, the optical transmittance of UV-B, UV-A and visible transmittance was 2.0 ~ 2.4%, 13.6 ~ 18.8% and 89.5 ~ 90.9%, respectively. Also, in the case of HMB samples, the optical transmittance of UV-B, UV-A and visible transmittance was 4.0 ~ 12.3%, 22.5~37.2% and 87.9 ~ 89.2%, respectively. Conclusions: Based on the results of this study, 2-ethylhexyl trans-4-methoxy-cinnamate with benzophenone materials were suitable for use as a material to UV-block hydrophilic lens.

목 적: 본 연구는 hydroxybenzophenone계 물질을 첨가제로 소량의 비율로 사용하여 소프트 콘택트렌 즈 제조 후 광학성 및 물리적 특성을 분석하여 콘택트렌즈 재료로서 활용도를 알아보았다. 방 법: 소프트콘택트렌즈의 주재료인 HEMA와 개시제인 AIBN을 기본조합으로 하고 2-hydroxybenzophenone, 2,4-dihydroxybenzophenone 그리고 2,4,4-trihydroxybenzophenone을 첨가제로 사용하여 각각 공중합하였다. 결 과: 2-Hydroxybenzophenone을 첨가한 콘택트렌즈의 경우 UV-A 86.8~72.2%, UV-B 84.2~70.4%로 소량의 자외선 차단 효과를 나타내었다. 또한 2,4-dihydroxybenzophenone 경우 UV-A 76.2~16.8%, UV-B 66.8~2.0%로 2,4,4,-trihydroxybenzophenone의 경우 UV-A 61.8~11.6% UV-B 50.8~1.4%로 두 물질 모두 자외선 차단 효과가 다소 있는 것으로 나타났다. 결 론: 본 실험 결과로 볼 때 소량 첨가하였을 때 2,4-dihydroxybenzophenone 및 2,4,4,- trihydroxybenzophenone의 경우 자외선 차단 기능을 가진 콘택트렌즈로 다양하게 사용될 것으로 판단된 다.

Purpose: In this study, the copolymers produced by adding the 2-hydroxypyridine and 4-hydroxypyridine were compared with the previous hydrogel contact lens materials. The utility of hydroxypyridine as a possible UV-blocking and high wettablility material for contact lenses was investigated. Methods: This study used 2-hydroxypyridine and 4-hydroxypyridine as additions with the cross-linker, EGDMA (ethylene glycol dimethacrylate), HEMA (2-hydroxyethyl methacrylate), AA (Acylic acid), MMA (methyl methacrylate) and the initiator AIBN (azobisisobutyronitrile) for thermal copolymerization. The mixture was heated at 115 ℃ for 50 mins to produce the hydrogel contact lens. Results: The polymer by using thermal polymerization process for hydrogel contact lens was produced and the physical properties which showed that the contact angle of sample containing 2-hydroxypyridine and 4-hyroxypyridine was in the range of 59.77~69.18° and 55.47~66.31°, respectively. The wettability of sample increased as the ratio of 4-hyroxypyridine increased. Also in case of 2-hydroxypyridine, the measurements showed that visible light 89.0~91.0%, UV-B 8.0~22.0%, UV-A 68.0~74.0% and in case of 4-hydroxypyridine, the results showed that visible light 88.0~91.0%, UV-B 79.0~81.0%, UV-A 84.0~86.0% respectively. Conclusions: The produced copolymer is suitable for hydrogel contact lenses with UV-blocking effect and high wettability.