This study examined the effects of pre-soaking solvents and repeated steaming-drying (SD) cycles on the antioxidant activity and active compound content of Rehmanniae Radix Preparata(RRP), the processed root of Rehmannia glutinosa Libosch. SD treatments were conducted for 1 to 9 cycles using four different pre-soaking solvents: Takju (a traditional rice wine), Spirits, Honey, and Sugar solution. The results showed no significant differences in DPPH and ABTS radical scavenging activities or in total polyphenol and flavonoid contents among the pre-soaking treatments, although samples pre-soaked in honey and Takju exhibited slightly higher levels. Polyphenol and flavonoid contents increased progressively with the number of SD cycles, reaching levels 2–3 times higher after nine cycles. Catalpol content remained relatively constant regardless of treatment, whereas aucubin content increased in all groups, with the highest accumulation observed in the Takju treatment. Similarly, 5-hydroxymethylfurfural (5-HMF) content increased with the number of SD cycles, with the highest levels found in the honey group, followed by Takju, Sugar, and Spirits. In conclusion, while the type of pre-soaking solvent had minimal influence on antioxidant activities and catalpol content, both aucubin and 5-HMF contents increased with additional SD cycles, with Takju proving particularly effective in enhancing their accumulation.

This study analyzes the discourse of Korean internet users regarding patient clothing and identifies the changes to structure and content of clothing resulting from infectious disease outbreaks. The analysis draws on texts from Korean blogs, internet cafes, and news articles from 2011 to 2021 related to patient clothing. Using Ucinet 5 and NodeXL 1.0.1 programs, network density, centrality, and cluster analyses were conducted using the Wakita–Tsurumi algorithm. Additionally, Latent Dirichlet Allocation (LDA) topic modeling was applied using Python 3.7 to further explore thematic patterns within the discourse. Throughout the period of study, it was found that users consistently discussed the specific purpose and functionality of patient clothing. Following the outbreak of COVID-19, the distribution and influence of keywords related to the functional aspects of patient clothing, such as “hygiene and safety,” significantly increased. An increased focus was placed on elements such as functionality, activity, autonomy, hygiene, and safety during the pandemic as public health concerns grew. It can be seen that patients increasingly share their experiences online and hospitalization rates surge during health crises; this study provides valuable insights into how the design of patient clothing can be improved through various informatics techniques. It underscores the evolving perception of patient clothing as essential medical equipment during health emergencies. In addition, it offers practical guidance for enhancing designs that better reflect shifting societal concerns, particularly regarding health, safety, and patient comfort.

장미 속은 오랜 시간에 걸쳐 잡종화, 배수화 및 육종 등을 통해 약 250개의 종과 30,000여 품종이 존재하는 진화 역사를 가지고 있으며, 다양한 분류체계로 구분되고 있다. 이에, 본 연구 는 장미 속 자원의 다양성을 평가하고 자생식물 해당화의 육종적 활용을 위해 수행되었다. 장미 속 자원의 형태학적 다양성을 확인하기 위해 장미 속 자원 303점에 대해 형태적 특성조사를 실시하고 해당화 및 장미 속 자원 29점을 선발하여 SSR 분석을 실시하였다. 추가적으로, 해당화의 육종적 활용을 위한 자원 6점 을 선발하고 화분 검정을 실시하였다. 본 연구의 결과, 장미 속 자원 303점의 다양성 평가 결과에서 유사한 형태적 특징을 지닌 자원끼리 7개 그룹으로 나뉘었다. 선발된 29개 자원의 형태학적 데이터와 분자학적 데이터를 이용한 군집 분석 결과, 데이터의 유사성을 보인 자원끼리 각각 5개, 4개 그룹으로 구분되었다. 또한, 혼합분석 시에는 3개 그룹으로 확인되었다. 분류 결과를 바탕으로 자생 식물을 이용한 정원장미 육종을 위해 각각 특성이 다른 해당화를 3점 선발하였고 장미 속 자원에 속하는 정원 장미 3점을 선발하여 총 6자원을 선발하였다. 선발된 자원의 화분 검정 결과, 종간 교잡체를 제외한 5가지 자원에서 90% 이상의 정상화분율을 확인하였다. 본 결과는 자생식물 해당화를 재평가 하고 정원 장미 육종 전략 수립에 도움이 될 것으로 기대된다.

Fas-associated death domain protein (FADD) functions as an apoptotic adapter in mammals, recruiting caspases for death-inducing signaling complexes, while in lower animals, it interacts with IMD and DREDD to initiate antimicrobial responses. In this study, we examined the T. molitor FADD sequence (TmFADD) using molecular informatics methods to understand its involvement in the host's immune response against microorganisms. Knocking down TmFADD transcripts resulted in increased susceptibility of T. molitor larvae to E. coli, underscoring the significance of FADD in insect defense mechanisms and providing valuable insights into insect immunity.

Tenebrio molitor(T. molitor) is gaining attention as a sustainable food source with high nutrient content. Understanding their immune system, paricularly the role of Tak1 in the Imd pathway, is essential for mass breeding. This study investigates TmTak1 function in T. molitor. we investigated the immune function of TmTak1, followed by systemic infection using E. coli, S. aureus, and C. albicans. As a result, Silencing TmTak1 significantly affects expression levels of AMPs in the whole body, Fat bodies, and Integuments. These results showed lower expression levels of AMP compared to the control group during E.coli injection.

Background: The forward head posture acts as a factor that can cause various neurovascular and musculoskeletal dysfunctions. But searching for a study on quality of life for patient with forward head posture was challenging. Therefore, this study aims to find the factors that most affect the quality of life in patients with forward head posture. Objectives: The purpose of this study was to investigate the correlations between the cranio-vertebral angle (CVA), neck disability index (NDI), pain, and sternocleidomastoid (SCM) thickness of patients with forward head posture and the quality of life of the patients and to figure out important factors that affect the quality of life of the patients with forward head posture. Design: Cress-sectional study. Methods: To measure the CVA, the angle at which the visible protrusion of C7 and the ear bead were connected was measured, and the neck disorder index was evaluated using the Korean version of NDI. The degree of pain of the subject was measured using a visual-analog scale (VAS). The SCM thickness was measured using an ultrasound imaging device, and the quality of life was evaluated using the Korean version of the World Health Organization quality of life questionnaire (WHOQL-BREF). Results: A significant predictive model showing 88% explanatory power for the dependent variable was confirmed, with an appropriate regression equation being found. The factor that most affected patients' quality of life in the forward head posture was confirmed by the SCM thickness. Conclusion: When applying an intervention to improve a patient's quality of life for patient with forward head posture, an intervention method that improves the SCM thickness should be recommended.

수국은 수국과(Hydrangeaceae) 수국속(Hydrangea)의 낙엽관목 식물로 크고 화려한 화형을 가져 절화, 분화 및 조 경수로 전세계적 인기가 있는 식물이다. 나무수국은 수국 (H. macrophylla)과 비교하여 삽목율이 낮은 것으로 알려져 있지만 나무수국의 묘목생산을 위한 삽목 연구 및 두 종간 삽목율 차이 원인 규명에 관한 연구는 미미하다. 본 연구는 IBA(Indol-3-butyric acid) 500mg·L-1 처리시 삽수의 침지 시간에 따른 삽목율 조사를 통해 적정 호르몬 처리 시간을 제 시하고 나무수국과 수국의 해부학적 구조 관찰을 통한 삽목율 차이 발생의 원인을 규명하고자 실시하였다. 나무수국의 적정 호르몬 처리 시간을 규명하기 위해 IBA 500mg·L-1을 무처 리, 30분, 2시간, 4시간 침지처리를 하였다. 종간 삽목율 차이 발생의 원인 규명을 위해 나무수국과 수국의 줄기 단면과 삽 목 후 시간 경과에 따른 발근을 해부학적으로 관찰하였다. 연 구의 결과 나무수국의 삽목시 IBA 500mg·L-1에 2시간 이상 침지처리가 다른 처리구와 비교하여 발근율이 높고 발생 뿌리 수가 가장 많았다. 또, 나무수국의 삽목율이 수국과 비교하여 낮은 것은 줄기의 세포 구조상 방사조직의 형태, 섬유세포의 밀도, 도관의 발달, 전분 함유 세포의 수 등에 차이가 관찰되 었고 이러한 세포 구조적 차이들의 영향으로 나무수국이 수국 보다 삽목 후 뿌리 조직 세포분열이 7일 늦게 시작되는 것이 확인되었다. 본 연구의 결과로 나무수국의 삽목 번식의 기초 자료로 활용되어 묘목 생산 효율 증대에 활용되길 바란다.

Emojis and avatars are widely used in online communications, but their emotional conveyance lacks research. This study aims to contribute to the field of emotional expression in computer-mediated communication (CMC) by exploring the effectiveness of emotion recognition, the intensity of perceived emotions, and the perceived preferences for emojis and avatars as emotional expression tools. The following were used as stimuli: 12 photographs from the Yonsei-Face database, 12 Memojis that reflected the photographs, and 6 iOS emojis. The results of this study indicate that emojis outperformed other forms of emotional expression in terms of conveying emotions, intensity, and preference. Indeed, the study findings confirm that emojis remain the dominant form of emotional signals in CMC. In contrast, the study revealed that Memojis were inadequate as an expressive emotional cue. Participants did not perceive Memojis to effectively convey emotions compared with other forms of expression, such as emojis or real human faces. This suggests room for improvement in the design and implementation of Memojis to enhance their effectiveness in accurately conveying intended emotions. Addressing the limitations of Memojis and exploring ways to optimize their emotional expressiveness necessitate further research and development in avatar design.