Brugada syndrome is associated with high risk for sudden death without structural cardiac defects due to ventricular arrhythmias. A 47-years-old man with Brugada syndrome has admitted because of right patella fracture. General anesthesia with sevoflurane and remifentanil was carefully maintained according to the BIS for the maintenance of adequate anesthetic depth and to avoid tachycardia during the surgery. Blood pressure and heart rate of the patient were maintained less than 150/90 mmHg and 100 beat/min perioperatively. There were no adverse events, and the patient was discharged home after ten days.

Background: We evaluated the effect of ulinastatin on paw withdrawal threshold (PWT), IL-6, and IL-10 in SD rats after spinal nerve ligation (SNL). Methods: Group C received N/S and Group E received ulinastatin IV for three days following SNL. PWT, IL-6, and IL-10 were measured on the 3rd, 5th, and 7th day. Results: Group E showed higher PWT compared to group C. IL-6 was lower in group E than in group C. No differences in IL-10 were observed between group C and group E. Conclusion: Ulinastatin increased the PWT and its effect appears to be involved with IL-6, not IL-10.