To achieve permanent disposal of radioactive waste drums, the radionuclides analysis process is essential. A variety of waste types are generated through the operation of nuclear facilities, with dry active waste (DAW) being the most abundant. To perform radionuclides analysis, sample pretreatment technology is required to transform solid samples into solutions. In this study, we developed a dry ashing-microwave digestion method and secured the reliability of the analysis results through a validity evaluation. Additionally, we conducted a comparative analysis of the radioactivity of 94Nb nuclides with and without the chemical separation process, which reduced the minimum detectable activity (MDA) level by more than 65-fold for a certain sample.

목적 : 한국 성인에서 성별과 연령에 따른 전안부 계측치(전방깊이와 전방각)를 평가하고자 하였다. 방법 : 평균 연령 35.38±15.75(20∼68)세의 92명 160안을 대상으로 하였다. 회전 샤임플러그 카메라(Pentacam, Oculus, Wetzlar, German)를 이용하여 안구 전안부를 측정하였다. 촬영된 샤임플러그 이미지에서 전방깊이와 전 방각의 평균값과 네 지점(상측, 하측, 코측, 그리고 귀측)에서의 방향별 측정값을 평가하였다. 결과 : 전체 대상자의 전방깊이는 평균 2.97±0.39 mm로 연령이 증가할수록 전방깊이가 얕아졌다. 코측(1.87± 0.39 mm)과 상측(1.85±0.39 mm)은 귀측(2.29±0.40 mm)과 하측(2.20±0.41 mm)보다 통계적으로 유의하게 얕 은 전방깊이를 보였으며, 4방향에서 모두 20대에서 60대로 갈수록 점차 전방깊이가 얕아졌다. 전방각은 평균 36.44± 6.76°로 연령이 증가할수록 전방각이 좁아졌다. 상측(34.23±7.52°)과 하측(33.27±6.76°)은 코측(38.28±7.28°) 과 귀측(39.98±7.13°)보다 통계적으로 유의하게 좁은 전방각을 보였으며, 4방향에서 모두 20대에서 60대로 갈수 록 점차 전방각이 좁아졌다. 결론 : 연령이 증가함에 따라 전방깊이는 얕아지고 전방각은 좁아졌으며, 연령증가에 따른 방향별 감소의 경향 이 다르게 나타났다.

Recent study showed that T cells in the immune organs and peripheral blood are influenced by estradiol, leading to a dysfunction of the immune system. However, little is known about the thymic-gonadal relationship during the estrous cycle in mouse. Therefore, the purpose of this study was to elucidate the mechanism by which a change in estradiol levels during the estrous cycle regulates the development of T cells in the mouse thymus. Six-week-old ICR mice were used and divided into four groups, including diestrous, proestrous, estrous, and metestrous. We first confirmed that ER-α and - β estrogen receptors were expressed in thymic epithelial cells, showing that their expression was not different during the estrous cycle. There was also no significant difference in thymic weight and total number of thymocytes during the estrous cycle. To determine the degree of thymocyte differentiation during the estrous cycle, we analyzed thymocytes by flow cytometry. As a result, the percentage of CD4+CD8+ double-positive (DP) T cells was significantly decreased in the proestrous phase compared to the diestrous phase. However, CD4+CD8- or CD4-CD8+ (SP) T cells were significantly increased in the proestrous phase compared to the diestrous phase. In addition, the percentage of CD44+CD25- (DN1) T cells was significantly decreased in the estrous phase compared to other phases, whereas the percentages of CD44+CD25+ (DN2), CD44-CD25+ (DN3), and CD44-CD25- (DN4) were not changed during the estrous cycle. These results indicate that the development of thymocytes may arrest in the DP to SP transition stage in the proestrous phase displaying the highest serum level of estradiol. This study suggests that a change in estradiol levels during the estrous cycle may be involved in the regulation of thymocyte differentiation in the mouse thymus.