Background: Flexible flatfoot impairs gait and posture by weakening arch support, potentially leading to musculoskeletal dysfunction. Strengthening exercises, such as the short foot exercise (SFE), have shown promise in correcting this condition. Objectives: This study aimed to investigate the effects of SFE with visual feedback on medial arch height and foot function in adults with flexible flatfoot. Design: Experimental research. Methods: Adults diagnosed with flexible flatfoot were randomly assigned to either an experimental or control group. The experimental group performed SFE with visual feedback, whereas the control group performed the same exercises without feedback. Both groups trained three times per week for five weeks. Outcome measures included the Navicular Drop Test (NDT), YBalance Test (YBT), and Tetrax postural analysis. Results: In the NDT, both groups showed significant improvements (P<.05), while in the YBT, only the experimental group showed a significant improvement (P<.05). In contrast, there were no significant changes in the Weight Distribution Index (WDI) and Stability Test (ST) areas of the Tetrax system in either group (P>.05). Conclusion: SFE effectively improved arch height regardless of visual feedback, though only the visual feedback group showed significant improvements in dynamic balance. However, between-group differences were not statistically significant, suggesting that visual feedback provides subtle rather than substantial additional benefits. Further research with larger samples is needed to establish the clinical value of adding visual feedback to SFE protocols.

본 연구는 보건계열 대학생을 대상으로 학습동기조절전략의 유형을 분 류하고, 이러한 유형에 따른 대학생 성공 및 삶의 만족도의 차이를 분석 하고자 하였다. G시 소재 대학 보건계열 학과(간호학과, 응급구조학과, 치위생학과)에 재학 중인 대학생 250명을 대상으로 한국형 학습동기조절 전략 척도, 대학생 성공 척도, 삶의 만족도 척도를 사용하여 자료를 수집 하였다. 수집된 자료는 군집분석, 다변량분산분석, 일원분산분석 등을 통 해 분석되었다. 연구 결과, 학습동기조절전략에 따라 '소극적 조절집단 (25.6%)', '중간 조절집단(39.6%)', '적극적 조절집단(34.8%)'의 세 가지 유형으로 분류되었다. 적극적 조절집단은 모든 전략에서 높은 점수를 보 였으며, 특히 사회적 인정/외적 보상 추구, 부모(교사)기대에 대한 보답, 공부에 대한 의무 등의 자기조절 전략에서 두드러진 활용 수준을 보였 다. 이러한 학습동기조절전략의 유형에 따라 대학생 성공의 모든 하위요 인과 삶의 만족도에서 유의미한 차이가 나타났다. 이러한 결과는 보건계 열 대학생의 학습동기조절전략이 학업적 성취를 넘어 대학생활의 다양한 측면에서의 성공과 전반적인 삶의 만족도와 밀접한 관련이 있음을 시사 한다.

Tyrosol, a phenylethanoid and a derivative of phenethyl alcohol, possesses various biological properties, such as anti-oxidative and cardioprotective activity. Olive oil is the principal source of tyrosol in the human diet. However, so far the anti-cancer activity of tyrosol has not yet been well defined. This study therefore undertakes to examine the cytotoxic activity and the mechanism of cell death exhibited by tyrosol in KB human oral cancer cells. Treatment of KB cells with tyrosol induced the cell growth inhibition in a concentration- and a time-dependent manner. Furthermore, the treatment of tyrosol induced nuclear condensation and fragmentation of KB cells. Tyrosol also promoted proteolytic cleavage of procaspase-3, -7, -8 and –9, increasing the amounts of cleaved caspase-3, -7, -8 and –9. In addition, tyrosol increased the levels of cleaved PARP in KB cells. These results suggest that tyrosol induces the suppression of cell growth and cell apoptosis in KB human oral cancer cells, and is therefore a potential candidate for anti-cancer drug discovery.

β-carotene is present in carrots, pumpkins, and sweet potatoes. It suppresses many types of cancers by regulating cellular proliferation and apoptosis through a variety of mechanisms. However, the effects of β -carotene on oral cancer cells have not been clearly established. The main goal of this study was to investigate the effects of β-carotene on cell growth and apoptosis in oral cancer cells. Our results demonstrate that treatment with β-carotene induced inhibition of cell growth, and that the effect was dependent on β-carotene treatment time and concentration in KB cells. Furthermore, treatment with β-carotene induced nuclear condensation and fragmentation in KB cells. β-carotene promoted proteolytic cleavage of procaspase-3, -7, -8 and –9 with associated increases in the concentration of cleaved caspase-3, -7, -8 and –9. In addition, the level of cleaved PARP was increased by β-carotene treatment in KB cells. These results suggest that β-carotene can suppress cell growth and induce apoptosis in KB human oral cancer cells, and that it may have potential usefulness in anti-cancer drug discovery efforts.

Curcumin (diferuloylmethane), a constituent of turmeric powder derived from the rhizome of Curcuma longa, has been shown to inhibit the growth of various types of cancer cells by regulating cell proliferation and apoptosis. However, a need exists to design more effective analogs because of curcumin's poor intestinal absorption. EF-24 (diphenyl difluoroketone), the monoketone analog of curcumin, has shown good efficacy in anticancer screens. However, the effects of curcumin and EF-24 on salivary gland epidermoid carcinoma cells are not clearly established. The main goal of this study was to investigate the effects of curcumin and EF-24 on cell growth and induction of apoptosis in human salivary gland epidermoid carcinoma cells. Our studies showed that curcumin and EF-24 inhibited the growth of HTB-41 cells in a dose- and time-dependent manner, and the potency of EF-24 was > 34-fold that of curcumin. Treatment with curcumin or EF-24 resulted in nuclear condensation and fragmentation in HTB-41 cells, whereas the control HTB-41 cell nuclei retained their normal regular and oval shape. Curcumin and EF-24 promoted proteolytic cleavages of procaspase-3/-7/-9, resulting in an increase in the amount of cleaved caspase-3/-7/-9 in the HTB-41 cells. Caspase-3 and -7 activities were detected in viable HTB-41 cells treated with curcumin or EF-24. These results suggest that the curcumin and EF-24 inhibit cell proliferation and induce apoptosis in HTB-41 human salivary gland epidermoid carcinoma cells, and that they may have potential properties as an anti-cancer drug therapy.