This study was conducted to investigate the physiological activities of the water and methanol extracts from Auricularia auricula-judae(black and brown) and Auricularia polytricha. Largely, anti-oxidant, anti-tumorigenic, anti-inflammatory, anti-diabetic activities were carried out. DPPH scavenging activity was performed on the anti-oxidant test. MTT assay and nitrite scavenging acitivity were performed on the anti-tumorigenic test. The cancer cell were used to HeLa, A549, HT-29 and MCF-7 and normal cell was used as control. lastly, in the anti-inflammatory and anti-diabetic activities, NO assay and α-amyloglucosidase inhibition were performed, repectively.

This purpose of this study was to analyze the nutritional composition about Auricularia spp., which has been used to Auricularia auricula-judae(black and brown) and Auricularia polytricha. First, the contents of total polyphenol and beta-glucan were analyzed. Subsequently, the contents of free sugars, amino acids and organic acids were analyzed by HPLC. In addition, the content of vitamin D from these strains was also measured and the D3 of this vitamin D was anlyzed. In conclusion, Auricularia spp. showed evident differences in the nutritional composition.

This study was carried out to investigate the effects of Hericium erinaceus extract on the Anti- inflammatory and Anti-bacterial. To investigate in vitro Anti-bacterial activity assay, hot water extracts of Hericium erinaceus carried out using a broth micro-dillution method following the Clinical and Laboratory Standards Institute guidlines(Citron and Hecht, 2003; Jorgensen and Turnidge, 2003). In the next experiment, to investigate anti-inflammatory test, the RAW 264.7 macrophage, cells was cultured using DMEM including the 10% FBS. Hericium erinaceus extract has the effects of anti-inflammation and, which may be due to its inhibitory potential on the macrophage activation. Furthermore, Hericium erinaceus extract has the anti-bacterial effects through the inhibitory Propionibacterium acnes(P. acnes) and periodontopathic bacteria, Porphyromonas gingivalis , Fusobacterium nucleatum and Tannerella forsythia. The above results suggest that Hericium erinaceus hot water extract could be applicable for improvement of several inflammatory disease.