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        검색결과 2

        1.
        2024.06 KCI 등재 구독 인증기관 무료, 개인회원 유료
        Obesity occurs when the body consumes more energy than it requires and uses less energy, resulting in the accumulation of fat, which increases the number and size of fat cells in the body. It causes high blood pressure, type 2 diabetes, and joint crowding, making it difficult to fully treat. We investigated the effects of chito oligosaccharide(CHO) functional material, which suppresses fat accumulation, restores dyslipidemia values, and has no side effects.In this study, we investigated the ameliorative effects of CHO on obese mice fed a high-fat diet. The experimental groups were divided into 5 groups (n=10) of C57BL/6 mice: normal control (N), control group (C), and chito oligosaccharide low concentration (L), medium concentration (M), and high concentration (H) groups. We tested whether CHO has an effect on obesity through body weight and adipose tissue weighing, serum lipid testing, and histological examination. Experimental analysis showed that CHO reduced body weight and adipose tissue weight, improved the concentrations of TCHO, TG, HDL, and LDL, which are factors for dyslipidemia diagnosis, and decreased the diameter size of adipose tissue. These results suggest that CHO alleviates the levels of fat growth inhibition and dyslipidemia levels in obese-induced mice, and has a positive effect on obesity.
        4,000원
        2.
        2021.09 KCI 등재 구독 인증기관 무료, 개인회원 유료
        Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the colon and rectum with intervals of acute exacerbation. Its etiology remains unknown, although recent studies suggest that pro-inflammatory cytokines initiate the inflammatory responses. In this study, we investigated the ameliorative effects of YB-21 (new product containining Lactobacillus plantarum, Barley Bran and Nymphaeaceae) in a dextran sulfate sodium (DSS)-induced colitis in mice. The experimental groups were divided into 6 groups (n = 10) of ICR mice: normal control(NC), DSS-treated(PC, positive control), DSS+latic-L-treated (3×107CFU/ml), DSS+latic-M-treated (3×109CFU/ml), DSS+latic-H-treated (3×1011CFU/ml), and DSS+YB-21-treated. Histological examinations indicated that YB-21 suppressed edema, mucosal damage, and the loss of crypts induced by DSS. Moreover, YB-21 reduced serum level expressions of, tumor necrosis factor-α (TNF-α). These results suggest that YB-21 has an anti-colitic effect by the suppression of intestinal inflammatory responses in DSS-induced colitis in mice.
        4,000원