Roller-compacted concrete (RCC) has been widely used for construction of pavements [1]. The strength of RCCP can be obtained from not only hydration of binder but also the aggregate interlock resulted from roller-compaction [2]. For this reason, RCCP normally achieves higher strength compared to conventional concrete pavement with similar cement content. Even though RCCP can be provided a good structural performance, it has been difficult to verify the long-term performance though actual field construction. Therefore, this study aimed to investigate the fatigue characteristics and crack development in RCCP based on full-scale fatigue test and accelerated pavement test. In case of full-scale fatigue tests, fatigue behavior was evaluated by using 1 m × 1 m dimensional RCC slab specimens obtained from the field in order to consider the field variability. Fatigue equation derived from this study shows that the number of load repetitions which causes fatigue failure at the same stress level is slightly larger than that of PCA fatigue equation. In order to evaluate the performance of RCCP, two phases of accelerated pavement test (APT) were conducted. In phase one, the performance of RCCP at two different strengths (35.6 and 30.4 MPa) was evaluated. In phase two, the performance of RCCP with different thickness (5, 7.5 and 10 cm) was investigated. The number of load repetition of fatigue crack occurrence in each section was compared to the estimated fatigue failure determined from fatigue equation of RCCP. The crack development in each section was compared to the AASHTO crack model for JPCP. Overall, it was confirmed that RCCP has equal or better performance compared to JPCP the estimation in term of fatigue cracking. The fatigue equation from PCA and cracking model from AAHTO can be used on RCCP at certain design thickness range.