Cementum is the mineralized tissue of the tooth. It is similar to bone in several aspects but it differs from bone. Human bone marrow stromal cells (BMSC) and human cementum derived cells (HCDC) (10,000 cells/cm²) were plated in 6 well plates as feeder cells. The next day, mouse bone marrow cells (1.5 million cells/cm²) were added. One group of these plates were incubated in serum-free conditioned medium (SFCM) generated from BMSC or HCDC supplemented with 2% FBS, parathyroid hormone (PTH), 1, 25 dihydroxyvitamin D₃ (Vit. D₃) and dexamethasone, or plain medium with the same supplements. Another group of plates were cocultured with BMSC or HCDC in plain medium supplemented with 2% FBS, PTH, Vit. D₃and dexamethasone. Plates grown without SFCM or coculture were used as controls. After 10 days, the cells were stained for tartrate-resistant acid phosphatase (TRAP). BMSC were found to support osteoclast formation under normal conditions. This was inhibited however by both SFCM generated from HCDC and also by coculture with HCDC. In addition, HCDC themselves did not support osteoclast formation under any conditions. Our results thus indicate that HCDC do not support osteoclast formation in vitro and that soluble factor (s) from HCDC may inhibit this process. In addition, we show that this inhibition also involves an active mechanism that is independent of osteoprotegerin, a feature that may distinguish cementoblasts from other cells present in periodontium.

Background: Small particles increase airway inflammation upon reaching the alveoli. Here, we investigated the protective or therapeutic effects of Salvia plebeia R. Br. (SP_R) extracts on airway inflammation. Methods and Results: To investigate the anti-inflammatory activity of SP_R extracts, we measured their inhibitory effect on the production of reactive oxygen species (ROS) expression of inflammatory mediators, and immune cell infiltration in MH-S alveolar macrophage cells and in the ambient particulate matter (APM)-exposed airway inflammation mice model. The SP_R extracts inhibited the production of ROS and expression of IL-4, IL-10, IL-15, and IL-17A mRNA in APM-stimulated MH-S cells. Oral administration of SP_R extracts suppressed APM-induced inflammatory symptoms, such as high alveolar wall thickness, excess collagen fibers, decreased mRNA expression of chemokines (Ccr9, Ccl5, Ccr3), inflammatory cytokines (IL-15, TNF-α), and IL-4 Th2 cytokine in the lung. The SP_R extracts also inhibited ROS production, granulocyte (CD11b+Gr-1+) infiltration, IL-17A, TNF-α, macrophage inflammatory protein (Mip-2), and chemokine (C-X-C motif) ligand 1 (Cxcl-1) production in the airway. The specific compounds in the SR-R extracts that mediate the anti-inflammatory effects were identified. Conclusions: In this study, SP_R extracts effectively inhibited airway inflammatory responses, such as ROS production and granulocyte infiltration into the airway, by regulating the expression of chemokines and inflammatory cytokines.

A new standard rose cultivar 'White Christmas' was bred from the cross between red standard cultivar 'Red Queen' and pink standard cultivar 'Vivaldi' at the National Horticulture Research Institute. The cross was made in 2001 and `White Christmas' was finally selected in 2006 after investigating characteristics for three years from 2003 to 2006. 'White Christmas', a white standard cultivar grows vigorously and has good flower shape. The major characteristics of this cultivar are 123.8 stems/m2/year in yield, 82.3 cm in length of cut flower, 11.0 cm in flower diameter, 60.1 in petal number, and 12.2 days in vase life. This cultivar can be propagated by both cutting and grafting. The consumer's preference of this cultivar is relatively higher than that of control cultivar, 'Tineke'.

A new standard rose cultivar 'Magic Pink' was bred from the cross between light yellow standard cultivar 'Medeo' and pink standard cultivar 'Veronica' at the National Horticulture Research Institute. The cross was made in 2001 and 'Magic Pink' was finally selected in 2006 after investigating characteristics for three years from 2003 to 2006. 'Magic Pink', a pink standard cultivar grows vigorously and has fashionable flower color. The major characteristics of this cultivar are 184.8 stems/m2/year in yield, 63.0cm in length of cut flower, 7.2 cm in flower diameter, 28.5 in petal number, and 10.4 days in vase life. This cultivar can be propagated by both cutting and grafting. The consumer's preference of this cultivar is relatively higher than that of control cultivar, 'Noblesse'.

A new oat (Avena sativa L.) cultivar 'Darkhorse' was developed by Honam Agricultural Research Institute (HARI) m2005. It was released because ofits earlmess, high forage yield potential and adaptability for late summer sowing. It was devel-oped from the a

spray cultivar “Yellow Mimi” at the National Horticulture Research Institute. The cros was made in 199 and the “Suny Lady”was finaly selected in 2003 after investigating characteristics for thre years from 2001 to 2003. “Sunny Lady”, a yellow spray2/year