기후변화와 세계시장 개방에 따른 외래 및 돌발해충의 종류는 다양해지고 밀도는 지속적으로 증가하고 있지 만 발생 실태에 관한 자료는 미흡하다. 본 연구는 경남지역 돌발 및 남방계 해충의 발생과 피해조사를 위해 미국선 녀벌레, 썩덩나무노린재, 담배거세미나방 등 3종을 경남 18시·군에서 조사하였다. 미국선녀벌레는 약충기(6월), 성충기(9월) 조사를 진행하였고, 길이가 50cm 이상되는 가지의 밑동에서 위쪽으로 50cm 내 개체를 육안조사하 였다. 썩덩나무노린재는 콩 개화기(7월), 등숙기(9월) 조사를 진행하였고 지점당 집합페로몬 트랩 1개를 설치하 고 1주 후 채집된 마리 수를 조사하였다. 담배거세미나방은 성페로몬 트랩 1개를 설치한 뒤 1주 후 채집된 마리 수를 조사하였다. 미국선녀벌레는 의령, 함안, 함양 등에서 발생이 많았고, 전년대비 발생이 소폭 감소하였다. 썩덩나무노린재는 합천, 밀양, 함양 등에서 발생이 많았고, 담배거세미나방은 전시군에서 발생이 확인되었으 며, 특히 함양, 산청, 사천, 고성 등에서 밀도가 높았다.

최근 기후변화에 따라 아열대 작물 재배가 증가하면서 경남지역 망고 재배면적도 크게 증가하고 있다. 하지만 망고에 발생하는 병해충 발생 정보가 부족하여 2022년부터 현재까지 경남지역에 있는 망고농장을 조사하였으 며, 그 결과 병해 6종, 해충 8종 발생을 확인하였다. 특히 경남지역 망고 포장에서 꽃노랑총채벌레, 대만총채벌레, 볼록총채벌레 등의 발생을 확인하였고, 통영, 함안, 밀양 등에서 총채벌레류에 의한 피해가 발생하였다. 많은 농가에서 총채벌레류 방제를 위해 화학농약에 의존하고 있으나 총채벌레는 반복적인 약제 노출시 빠른 세대 진전으로 인해 저항성 발달이 쉽기때문에 방제에 어려움을 겪고 있다. 이러한 문제를 해결하고자 색상별 끈끈이 트랩의 총채벌레류 유인효과를 확인하였으며, 꽃노랑총채벌레는 노랑, 주황, 연두, 대만총채벌레는 빨강, 노랑, 파랑, 볼록총채벌레는 파랑, 노랑, 빨강 순으로 유인효과가 높은 것을 확인하였다.

The clinical importance of biologic markers remains elusive in gastric cancer. The aim of this study was to evaluate the prognostic value of p53, Ki-67, and COX-2 in gastric cancer. This retrospective study examined based on medical records of postoperative immunohistochemical test of 176 patients who demonstrated high expression of all three biological markers being tested (p53, Ki-67, and COX-2), among 357 gastric cancer patients who underwent surgical resection consecutively. This study demonstrates the correlation with biologic marker between clinical relationship and recurrence free survival (RFS). A positive correlation was observed between the expression of Ki-67 and p53, and a positive correlation was also observed between the expression of Ki-67 and COX-2 Expression of p53 did not correlate with any of the clinicopathological variables examined. Both Ki-67 and COX-2 expression significantly correlated with tumor depth, classified as early gastric cancer and advanced gastric cancer. The expression of COX-2 significantly correlated with tumor differentiation, with more tumors being of the undifferentiated type than of the differentiated type in the COX-2 positive group. A significant difference between p53 and RFS, also COX-2 expression and RFS was observed. This study showed that only p53 and COX-2 have significantly correlated with the RFS of gastric cancer.

Background : Methicillin-Resistant Staphylococcus aureus (MRSA) is a multidrug-resistant (MDR) strain. Especially, MRSA is developing resistance to available antibacterial agents and causing complications in the treatment of infections related to skin, soft tissue, respiratory, bone, joint, and endovascular disorders. Therefore, antibacterial agent combination therapy appears to be a useful option, particularly in developing countries where antibiotic availability is limited. (+)-Usnic acid (UA) is uniquely found in lichens, and is especially abundant in genera such as Usnea and Cladonia. UA has antimicrobial activity against human and plant pathogens. Therefore, UA may be a good antibacterial drug candidate for clinical development. Methods and Results : In search of a natural products capable of inhibiting this multidrug-resistant bacteria, we have investigated the antimicrobial activity of UA against MRSA. In this study, the effects of a combination of UA and permeable agents against MRSA were investigated. For the measurement of cell wall permeability, UA with concentration of Ethylenediaminetetraacetic acid (EDTA) was used. In the other hand, Sodium azide (NaN3) was used as inhibitors of ATPase. These results suggest that the antibacterial effect of UA was potentiated by membrane-binding agents and ABC transporter-inhibiting agents, implying that antibacterial activity is associated with damage of the cell wall and inhibition of ATPase function by UA. Conclusion : UA and in combination with EDTA and NaN3 could lead to the development of new combination antibiotics against MRSA infection. The results of this study appear to be promising, and they are expected to enhance the use of natural products as drugs.

Esophagojejunostomy after total gastrectomy shows high mortality and morbidity. Complication after esophagojejunostomy was caused by constant tension on esophagojejunostomy in erect-position, resulting in disturbance of blood flow in the anastomotic site. The purpose is to evaluate efficacy of anchoring sutures. Medical charts of patients diagnosed with gastric cancer who underwent total gastrectomy from 1998 to 2008 were analyzed retrospectively. Anchoring suture between jejunum and diaphragm after esphagojejunostomy was performed in all patients. A total of 155 patients were enrolled. Esophagojejunostomy leakage 3, revision operation 2, and conservation 1. Esophagojejunostomy stenosis 1, which was improved by balloon. This procedure could protect the esophagojejunostomy site from traction force.

Laparoscopic appendectomy using three trocars has been widely performed. Recently, a single incision laparoscopic surgical procedure has become popular because it is less invasive. We report on our early experience in performance of single incision laparoscopic appendectomy (SIL-A). Data on the operating time, the duration to make the pneumoperitoneum, body mass index (BMI), rate of conversion to another operation, complication, hospital stay, dosage of analgesics, and pain score were collected prospectively at two centers. Twenty seven patients underwent SIL-A. The mean BMI was 23.3±3.1 kg/m2 (17.6-30.5). The mean time required to make a pneumoperitoneum was 9.9±5.0 minutes (5.0-28.0). The mean operating time was 37.6±26.7 minutes (10.0-100.0). The rate of intra-operative complication was 3.7% (1/27), and the rate of post-operative complication was 22.2% (6/27). The mean hospital stay was 4.1±1.2 days (2-6). The immediately postoperative pain score was 5.4±1.5 (3-8), however, the pain score at discharge was 0.4±0.7 (0-2). The mean dosage of analgesics was 1.5±1.3(0-4), however, none of the patients took analgesics after postoperative three days. SIL-A is feasible but requires improved instrumentation and experience.

The aim of this study is to evaluate satisfaction with critical pathway (CP) in nursing gastric cancer patients. From January to June 2008, non critical pathway group (NCPG, n=28) is used by general doctor’s order. However, from July to December 2008, critical pathway group (CPG, n=25) received the CP schedule applied by the PA on the pre operative day. The collected data were analyzed by chi-square, and student t-test using the SPSS/Win 12.0 program. Patient’s satisfaction increased with understanding of disease and treatment process, explanation of related study and treatment, education regarding activity status, and degree of confidence in doctor. Patient satisfaction was higher in the CPG than in the NCPG.