Purpose: The purpose of the present study was to examine the physical and psychological benefits afforded by a 6-week yoga program for breast cancer survivors. Methods: Eligible participants (per-screened) were to the intervention group 17. All participants completed pre- and post-testing assessments immediately before and after the Mindfulness yoga program. Statistical analyses were paired samples t-test by SPSS 19.0. Results: The Mindfulness yoga program participants(female) included primarily breast cancer survivors, on average 46.5 months post-diagnosis. Significant differences between pre and post at post-intervention were seen only in psychosocial(i.e. QOL; Role function, Appetite loss, Constipation and PSQI) Finally, there were also significant improvements in the program participants from pre- to post-intervention on physical variables(Weight, BMI). Conclusion: The mindfulness yoga program has a positive effect on Quality of life in Breast cancer survivors. Future research might attempt to include control group and a longer program duration.