Bortezomib (BTZ) and dasatinib (DA) are two substantial anti-cancer agents with side effects on the human body. In this research, we fabricated a novel electrochemical sensor modified by CuFe2O4/ SmVO4 nanocomposite and 1-ethyl-3-methylimidazolium chloride (1E3MC) as an ionic liquid (IL) ( CuFe2O4/SmVO4/IL/CPE) for coinciding investigation of BTZ and DA for the first time. The CuFe2O4/ SmVO4 synthesized were determined and certified through field-emission scanning electron microscopy (FE-SEM), energy diffraction X-ray (EDX), and X-ray diffraction (XRD). The capability of the sensor was investigated by different electrochemical techniques such as cyclic voltammetry (CV), chronoamperometry (CHA), differential pulse voltammetry (DPV), and electrochemical impedance spectroscopy (EIS). The attained data showed that the oxidation signal of bortezomib and dasatinib promoted as an innovative electrochemical sensor. After optimization of the conditions using this sensor at pH 7.0, the oxidation signal of bortezomib and dasatinib showed to be linear with drug concentrations in the range of 0.09–90 μM and 100–500 μM with a detection limit of 5.4 nM and 7.0 μM, respectively, using differential pulse voltammetry method. The values of D and electro-transfer coefficient (α) achieved 2.5 × 10− 5 cm2 s− 1 and 0.99, respectively. The proposed electrochemical sensor exhibited acceptable selectivity and sensitivity for simultaneous detection of bortezomib and dasatinib in pharmaceutical and biological samples.

전파를 이용한 실내 위치인식 기술은 현재 다양한 환경에서 연구되고 있다. 그 중 철골구조로 이루어진 선박은 전파의 반사에 의해 수신율은 높지만 레인징 오차가 크게 발생한다. 이러한 환경에서 발생하는 위치측정 오차를 줄이기 위하여 본 연구에서는 IEEE 802.15.4a의 CSS 기반으로 변형 이변측위와 초전센서를 이용한 선내 위치인식보정 알고리즘을 제안한다. 제안한 시스템은 선내 복도와 같은 좁은 통로에서 CSS의 특성분석을 통하여 이동노드와 고정노드 사이의 적합한 수신거리를 추정하여 고정노드의 수를 줄이고 또한 전파의 반사와 회절에 의한 레인징 오차가 크게 변동하는 코너영역에서 제안한 변형 이변측위기법과 초전센서를 이용하여 이동구간을 추적하여 위치를 인식하였다. 실험결과 제안한 알고리즘이 일반적인 방법 대비 86.2 %의 선내 위치인식 정확도와 효율이 향상됨을 확인하였다.

A investigation of electrochemical analysis of antibiotics Neomycin (C23H46N6O13) was searched using electrochemical square wave (SW) stripping and cyclic voltammetry (CV) using working sensor of the modified carbon nanotube combination electrodes, optimum diagnostic parameters were searched by anodic stripping, final conditions were attained to working range of 1.0-14.0 ng/L, detection limit (S/N) was found to be 0.6 ng/L. The developed method was discovered to be fitting in quality control in the food, pharmaceutical and other manufacturing sectors.