Neurilemmomas, also known as schwannomas, are typically benign, well-encapsulated, slow-growing tumors originating from Schwann cells which encompass peripheral motor and sensory nerves. Neurilemmomas in parapharyngeal space (PPS) are very rare, but they can occasionally originate from the last four cranial nerves and autonomic nerves. In this article, we report the rare case of a 47-year-old male presenting solitary neck swelling and hoarseness. After computed tomography and magnetic resonance imaging, we performed complete surgical excision by a transcervical approach under general anesthesia. In the histologic examination, Neurilemmoma was diagnosed. The patient did not complain of any specific complications, showed good prognosis without recurrence or pain up to date.

Myoepithelioma is a rare tumor that seldom occur in the parapharyngeal space region. And an accurate diagnosis of myoepithelioma is very difficult due to its unusual location and cellular variation. Therefore, misdiagnosis of this neoplasm as more aggressive tumor can lead to unnecessary treatment. We experienced extremely rare case of myoepithelioma arising in the deep lobe of parotid gland that is extended in the parapharyngeal space and reported it to a literature review.