In this study, 102 residents in Gwangyang and Yeosu were evaluated for exposure to levels of urethral arsenic from April 2017 to June 2018. The geometric mean concentration of the urinary arsenic in the total studied was 154.30 μg/L, with the figure for the Gwangyang area being 201.18 μg/L and the figure for the Yeosu area being 200.21 μg/L, which signifies that there was no real difference between the two regions. The figures for males and females were 173.81 μg/L and 136.98 μg/L, respectively, indicating higher levels for males. In the case of males, the risk assessment of arsenic (As) showed that 0.54 does not exceed 1 and approximately 11.3% exceeded the reference value. For women, the number of hazardous materials did not exceed 1.41 and approximately 5.1% exceeded the reference value of the total arsenic exposure survey.