The goal of this study was to measure the indoor and outdoor fine and ultrafine particulate matter concentrations (PM10, PM1.0) of some houses in Yeosu and in S university in Asan from March to September 2018. PM10 concentration in indoor air in Yeosu area was 18.25 μg/m3, while for outdoor air it was 14.53 μg/m3. PM1.0 concentration in indoor air in the Asan area was 1.70 μg/m3, while for outdoor air it was 1.76 μg/m3, showing a similar trend. Heavy metal concentrations in the Yeosu region were the highest, at Mn 2.81 μg/m3, Cr 1.30 μg/ m3, and Ni 1.11 μg/m3 indoors. Outside, similar concentrations were found, at Cr 3.44 μg/m3, Mn, 2.60 μg/m3, and Ni 1.71 μg/m3. Our analysis of indoor and outdoor PM concentrations in the Asan region, which was carried out using the MOUDI (Micro-orifice Uniform Deposit Impactor) technique, found that PM concentration is related to each particle size concentration, as the concentration of 18 μm and 18-10 μm inside tends to increase by 3.2- 1.8 μm and 0.56-0.32 μm.

In this study, 102 residents in Gwangyang and Yeosu were evaluated for exposure to levels of urethral arsenic from April 2017 to June 2018. The geometric mean concentration of the urinary arsenic in the total studied was 154.30 μg/L, with the figure for the Gwangyang area being 201.18 μg/L and the figure for the Yeosu area being 200.21 μg/L, which signifies that there was no real difference between the two regions. The figures for males and females were 173.81 μg/L and 136.98 μg/L, respectively, indicating higher levels for males. In the case of males, the risk assessment of arsenic (As) showed that 0.54 does not exceed 1 and approximately 11.3% exceeded the reference value. For women, the number of hazardous materials did not exceed 1.41 and approximately 5.1% exceeded the reference value of the total arsenic exposure survey.

In this study, 40 residents of the Gwangyang and Yeosu areas were assessed for their level of exposure to heavy metals (As, Cd, Ni) from April 2017 to June 2018. The aim was to understand the differences in levels of indoor exposure to heavy metals (As, Cd, Ni), and a health risk assessment was conducted to determine whether there was any fatal cause from carcinogenic elements. The mean concentrations of PM10 particles indoors were As 0.24 μg/m3, Cd 0.07 μg/m3, and Ni 0.89 μg/m3. The health risk assessment for the arsenic, cadmium, and nickel in indoor air confirmed that the mean values exceeded the cancer risk tolerances specified by the U.S. EPA, for As (males 3.07 × 10−4, females 3.35 × 10−4), Cd (males 3.83 × 10−5, females 4.18 × 10−5), and Ni (males 6.36 × 10−5, females 6.95 × 10−5).

To obtain basic data on bioaerosols in the indoor environments of houses located adjacent to Gwangyang Iron Works, the concentration and diversity of indoor air molds were comparatively investigated in 33 houses in September of 2016 and 2017, respectively. In areas both adjacent to and nonadjacent to Gwangyang Iron Works, house temperature and humidity ranged from 24~28oC and 47~57%, respectively. Airborne mold concentration was higher in the houses located nonadjacent than in the ones adjacent to the iron works. Interestingly, the level of airborne mold concentration exceeded 500 CFU/m3 in all houses nonadjacent to the iron works. A total of 12 mold species including five pathogenic species were indentified from the investigation. Among the five pathogenic species, the causal agents of otomycosis, Alternaria alternata, Aspergillus fumigatus, and A. niger were present. Overall, Cladosporium cladosporioides was the dominant species. This is the first report on the concentration and diversity of airborne mold in houses located adjacent and nonadjacent to Gwangyang bay industrial complex in Korea.

This study was conducted targeting 30 residents of Gwangyang industrial complex area from April to May 2017 to assess their level of exposure to VOCs and conduct a health risk assessment for individual exposure. The aim was to understand the difference in levels of indoor, outdoor and personal exposure to VOCs (benzene, toluene, ethylbenzene, m-xylene, p-xylene, o-xylene) and a health risk assessment was conducted to determine whether there was any fatal cause from carcinogenic or non-carcinogenic elements from a respiratory disease patients. In the case of benzene in the air, the geometric levels of the group are indoor, outdoor and personal exposure; on the CTE, RME condition and Monte-Carlo analysis, all subjects were seen to exceed the carcinogenicity tolerance of 10−6 specified by the US EPA. In the case of toluene, ethylbenzene, m-xylene, p-xylene, o-xylene on the CTE, RME condition and Monte-Carlo analysis, the non-carcinogenic standard of 1 was not exceeded.

This study was carried out to investigate the presence of a correlation between heavy metals in urine samples and upper airway diseases. For the study, 51 household residents of Gwangyang, both with and without upper airway disease, were targeted. Urine samples were collected from the subjects along with a questionnaire from April 24th to 27th, 2017. The heavy metals in the urine samples were preprocessed and analyzed using an inductively coupled plasma/mass spectrometer. The geometric mean concentration of urinary arsenic and cadmium was 138.66 μg/L and 0.75 μg/g creatinine among those with upper airway disease and 166.42 μg/L and 1.19 μg/ g creatinine among those without upper airway disease. This was not a statistically significant difference. The concentration of urinary arsenic and cadmium was found to be increased by 1.19 times (95% CI; 0.15-9.31) and 1.26 times (95% CI; 0.31-5.04) in household residents with upper airway diseases with more than 144.86 μg/L and 0.85 μg/g creatinine, respectively.

The purpose of this study was to evaluate the concentration of airborne particulate matter and heavy metals in the houses of the respiratory tract disease patients and a control group of residents in the city of Gwangyang. The particulate matter was measured using a mini-volume air sampler and then weighed three times using a micro balance to calculate the weighted average value. The heavy metals in the particulate matter were extracted using a hot plate and analyzed using an inductively coupled plasma/mass spectrometer. The average concentration of particulate matter in the outdoor air (34.478 μm/m3) was higher than that in the indoor air (16.794 μm/m3), showing a statistically significant difference (p<0.001). The average concentration of copper, manganese and chromium in the indoor and outdoor air were higher in the houses of those in the study group than those of the control group. In addition, there was a generally high correlation between particulate matter in the outdoor air and heavy metals in the indoor and outdoor air concentration (p<0.05).

Mold is one of the important bio-aerosols affecting human health in the indoor environment. To manage mold contamination, it is necessary to use an appropriate method for its detection and enumeration. Recently, the impaction method of ISO 16000-18 has been established as one of methods to detect and enumerate molds in air. To investigate the general use of the impaction method for mold detection in domestic indoor environments, the suitability of the method was assessed using different antibiotics, media and air samplers. All of the three antibiotics tested - ampicillin, chloramphenicol and streptomycin - showed inhibitory effects on bacterial colony formation on MEA and DG-18 media, without inhibiting mold growth. Of these three antibiotics, ampicillin was the most effective. There was no statistical difference between MEA and DG-18 media in the measurement of mold concentration. The formation of discriminative colony morphology was more apparent in DG-18 media. No significant difference in the measurement of mold concentration was found between Andersen samplers and MAS- 100NT samplers, which are two major samplers introduced in Korea.

This study measured and analyzed the heavy metal (Cd, As) content of fine dust in the city of Gwangyang, Jeonnam from September 19 to September 22, 2016. For cadmium, the arithmetic average was 0.21 ng/m3 (0.12~0.49 ng/ m3), which did not exceed the WHO's recommended level. The average of arsenic was 2.41 ng/m3 (0.30~142.08 ng/ m3) and the geometric mean was 11.18 ng/m3, which exceeded the WHO's recommended standard in 16 out of 24 measurements. In the case of cadmium, the CTE of male was 9.22 × 10−8 RME 1.91 × 10−7 and the female CTE was 9.44 × 10−8 RME 1.92 × 10−7, which did not exceed the EPA limit of CTE 2.18 × 10−5 RME 1.51 × 10−4 for men and CTE 2.23 × 10−5 RME 1.51 × 10−4 For women, CTE 2.23 × 10−5 RME 1.51 × 10−4 results were obtained, which exceeded the EPA's recommended limit and also exceeded the maximum allowable limit of 10-4.

The study measured the volatile organic compounds consistency of the child tympanitis patient family. Benzene, the result which analyzes toluene, ethylbenzene, xylene and TVOC consistency, case of personal exposure they were 0.518 μg/m3, 0.909 μg/m3, 1.299 μg/m3, 0.960 μg/m3 and 273.718 μg/m3 respectively, case it appeared with benzene the interior 0.539 μg/m3 and toluene 1.433 μg/m3 and ethylbenzene 1.253 μg/m3 and xylene 1.899 μg/m3 and TVOC 262.132 μg/m3. The consistency of the outdoor benzene, toluene, ethylbenzene, xylene and TVOC appeared respectively with 0.512 μg/m3, 0.474 μg/m3, 1.177 μg/m3, 0.862 μg/m3 and 22.306 μg/m3. Personal exposure, the residential interior, interrelationship analytical result Benzene of outdoor consistency and Ethyl benzene, Xylene and TVOC personal exposures with the interior and outdoor consistency showed the interrelationship which considers(p < 0.01). VOCs consistency which it follows in residential type the detached home > the multi generation house > the consistency price came out with the apartment order, VOCs consistency which it follows construction year possibility the year valence which is built 4 years at once rises the consistency appeared more highly the case where the case is above 4 years than.

본 연구는 돼지의 성별에 따른 거세와 난소 적출이 체성장과 사료 이용성, 혈중 호르몬 농도에 미치는 영향을 구명하기 위하여 축산기술연구소에서 계통 조성중인 35일령의 돼지 48두를 이용하여 실시하였으며, 얻어진 주요 결과를 요약하면 다음과 같다. 1. 체성장 및 사료 이용성 산육능력에 있어서 암퇘지 난소 적출구의 일당증체량은 898.6 g으로 대조구의 862.7 g보다 높게 나타났으나 유의차는 없었고, 수퇘지 거세구의 일당증체 량은 926.0 g으로 대조구의 945.5 g 보다 약간 낮았으며, 유의차는 없었으나, 수퇘지 대조구는 암퇘지군 보다 일당증체량이 높게 나타났다. 사료요구율은 수퇘지 대조구가 2.51로 가장 낮게 나타났으며 암퇘지군에 비해 유의하게 낮았으나 거세구와의 유의차는 없었으며, 난소 적출구와 대조구와는 차이가 없었다. 등지방 두께는 수퇘지 대조구가 1.65 cm로 가장 낮게 나타났고, 암퇘지군과 유의차는 없었으며, 각각의 대조구가 시험구에 비해 유의하게 낮게 나타났다. 2. 혈중 호르몬 변화 혈중호르몬 변화에 있어서 IGF-I 농도는 암퇘지군 대조구에서는 5주령의 45.1±0.72ng/m1에서 15주령의 356.3±3.05ng/ml까지 점차적으로 높은 경향을 나타내었으나, 그 이후부터 23주령까지 일정한 수준으로 유지되었다. 수퇘지 군에서도 혈중 IGF-I 농도 변화는 암퇘지와 비슷한 경향을 보였으나 전구간에서 암퇘지 군에 비해 수쾌지 군이 다소 높은 경향을 보였다. 한편, 거세 및 난소 적출구의 경우에는 각각의 대조구에 비해 다소 낮은 경 향치를 나타내었다. 혈중 스테로이드 호르몬 변화에 있어서 대조구 암퇘지의 혈중 estradiol-l7β 농도는 5주령에서는 극히 낮은 수준이었으나, 그 이후 11주령의 21.8±1.61pg/ml에서 23주령까지 점차 증가되었다. 또한 대조구의 혈중 progesterone 농도는 5주령에 비해 11주령 이후부터 다소 높은 농도를 나타내었다. 반면에 난소적출된 암퇘지에 있어서는 estradiol-17β와 progesterone 농도는 거의 검출한계 이하로 나타났다. 한편, 수퇘지의 testosterone 농도는 대조구의 5주령에서는 0.28±0.17ng/ml로 낮은 수준이었으나 11주령에서는 4.63±0.78ng/ml로 증가되었으며 그 후 23주령까지 유의적으로 증가되었다. 이에 반해 거세돼지의 경우에는 23주령까지 전혀 검출이 되지 않아 거세돼지의 경우 혈중 testosterone은 거의분비가 되지 않는 것으로 나타났다.

This experiment was canied out to investigate the effect of seeding times on the fresh yield of fodder beet varieties, and to select the most adaptable varieties of fodder beet in Daekwanryeong areas. Three varieties(Kyros, Zorba and Hugin) and six seedin

This experiment was carried out to develop the model system for mass production of biomedical and nutritional proteins (human proteins) through mamraary gland of the transgenic cattle produced by gene manipulation and embryological technologies. Human growth hormone gene fused with rat -casein gene promoter was microinjected into pronuclei of one cell bovine embryos produced by in vitro fertilization. After microinjection, embryos were cultured in vitro for 6 or 7 days. Twenty embryos reaching to blastocysts were transferred to 10 beef recipients, each receiving two embryos. Recipients were diagnosed for pregnancy by rectal palpation at 76 days after embryo transfer. One of them was pregnant to term and produced a female calf weighing 21 kg at 280 days following embryo transfer. DNA was extracted from umbilical cord tissue and blood of calf born for confirming gene insertion. As determined by Southern hybridization, the transgene was not found.