Bovine papillomaviruses (BPVs) are DNA oncogenic viruses that belong to the Papillomavirus genus. The purposes of the present study were to histopathologically diagnose skin warts on Korean native cattle from Jeju Island and to detect the presence of BPVs from tissue samples of the skin warts, using the polymerase chain reaction (PCR) assay. The sites of 10 skin wart involvement were the head (40%: 10% were in both the head and neck), shoulder (30%), neck (20%), and tail (20%), including the perineum. All skin warts were confirmed as fibropapillomas, as characterized by the abundant proliferating fibrous tissue in the dermis and increased epithelial covering of variable thickness. According to the PCR analysis, five out of 10 (50%) cattle were positive for BPV-1, and six (60%) cattle were positive for BPV-2. Two cattle were positive for both BPV-1 and BPV-2. To the best of our knowledge, this is the first study of BPV-1 and BPV-2 infections of skin warts from Korean native cattle in Korea.

The object of this study were twofold, namely, to study on (1) effect of using ultrasound therapy for curing warts (2) any relation between a cure for warts and onset of warts, as well as subject age. Our subjects, composed of 22 people from age 12 to 49, were assigned to two groups, experimental group and control group. We experimented for 8 session on 12 people in the experimental group by using ultrasound therapy to observe any morphological change in the warts or disappearance of a pain. However, we did not cure warts in the other group, control group. The result of the study are as follows. (1) Ultrasound therapy has an effect on curing warts. (2) Neither condition, onset of warts or subject age, had no influence on a cure for warts.