The pet industry, especially pet food, is experiencing rapid growth. This growth is accompanied by increasing concerns about pets' gut health, as an imbalanced microbiota can lead to various diseases. This study analyzes global patent trends in microbiome-based technologies for treating pet digestive issues using the WIPS database across major markets. Of 1,194 patents identified, 394 key references were examined, highlighting the increasing number of probiotic and microbiome-related patents since 2016. China dominates this sector, followed by Korea, Japan, and the United States. The findings provide a foundation for advancing microbiome-driven solutions for pet digestive ailments.

This study was conducted to collect the patents of microbiome-based treatment technology for pets. An electronic search for microbiome or probiotics in brain nervous system disease was studied using the WINTELIPS database. Patent Cooperation Treaty of Korea, Japan, the EU, the US, and China that were registered by October 31, 2022 were selected in this study. A total of 206 patents were included for final analysis. Since 2016, patent activity has shown an explosive increase in recent years. China is the leading market in this technology field, and Korea has the second-highest market share. To provide the groundwork for the next research and development, we examined the industrial trend of microbiome for brain nervous system diseases in this study using an analysis of patents that have been applied for and registered up to this point. Looking at the overall patent trends by year in the technology field related to treating of brain and nervous system diseases using the microbiome, there was a tendency to repeat increasing and decreasing trends. However, considering 2021 and 2022, which have undisclosed sections, it can be seen that patent activity has tended to increase explosively in recent years, starting in 2016. If related studies use the patent analysis data constructed in this way strategically, it is expected that it will lead to patent registration and the development of new products, ultimately contributing to the revitalization of the companion animal industry.

피부에는 박테리아, 바이러스, 곰팡이를 포함하는 마이크로바이옴이 인체세포와 공존하고 있으 며, 최근 피부 및 화장품 분야에서 피부 미생물 구성물과 피부 건강, 질병과의 연관성에 대해 많은 연구가 이루어지고 있을 뿐만 아니라 마이크로바이옴 화장품의 개발이 활발한 상황이다. 피부 마이크로바이옴은 매우 다양하며, 피부에서 구성비나 서식하는 부분이 다르지만 다양한 방법으로 상호작용을 통해 피부의 영 양을 공급하거나 경쟁자인 병원균의 증식을 제한하고 있지만, 피부 마이크로바이옴과 병원균의 균형이 깨 지면 면역 항상성의 파괴에 기여하고 피부 질환의 발병으로 이어질 수 있다. 이에 따라 본 논문은 우리 피 부에 공생관계인 피부 마이크로바이옴의 역할과 연구 동향에 대해 파악하고, 마이크로바이옴 균형에 도움 이 되는 바이오틱스 소재에 관한 산업동향을 고찰함으로써 미래의 큰 성장 가능성을 가진 피부 마이크로바 이옴 시장의 중요한 자료로 사용될 수 있을 것으로 사료된다.