7 new sericinjams are in breeding by the hybridization of silkworm genetic resource, that is, ND strain and the parent silkworm, and the feature of new sericinjam was classified by a cocoon color. According to cocoon color, sericinjam showed two kind of color including the light green and yellow. D601, D704 and D707 with the light green silk were a difference to density of color. Also D703, D705, D751 and D752 with the yellow silk showed a difference to density of color. As investigating the pupation rate which means the healthiness of the silkworm, D601 was highest with 93%, and D703 was lowest with 65.6%. The ratio of the sericin silk showed some difference every breed, and D601 among them was highest with 91%. There is close correlation between sericin cocoon quantity and the dried silkgrand weight. The weight of the dried silkgrand for sericinjams which were compared with baeokjam was low about 2.5 ~ 7.9 times. Among sericinjams, D601 was lowest, and D707 was highest. The pure sericin content of sericinjams was an above 96%, and sericin content of per one cocoon was low 1.4 ~ 2.5 times than baeokjam. Blood of silkworm which makes the light green silk exhibited anti bacterial activity against Gram-negative bacteria.
본 논문에서는 세리신잠 실샘 가수분해물(Sericinjam Gland Hydrolysate: SJGH)을 이용하여 진피 섬유아세포에서 항산화 및 항노화 연구를 진행하였다. SJGH는 사람 섬유아세포에서 고농도의 과산화수소에 의한 세포 사멸과 세포 내 산화 증가를 효과적으로 방어하였다. 또한 SJGH는 저농도의 과산화수소에 의한 섬유아세포의 SA-β-Gal 발현과 MMP-1의 발현 증가를 억제하였고, 반대로 프로콜라겐 I의 생합성은 증가시켰다. 이러한 결과를 통해 SJGH의 항산화 및 항노화 효과가 우수함을 확인하였으며, SJGH가 항노화 화장품의 우수한 소재가 될 수 있음을 보여준다.