Ankylosing spondylitis (AS) is an inflammatory joint disease affecting the axial skeleton, peripheral joints, entheses, and extra-articular site. Non-steroidal anti-inflammatory agents are the first line drugs for treatment of AS. Sulfasalazine is regarded as the second line drug and is usually used on AS patients with concomitant peripheral arthritis. Sulfasalazine has side effects, including liver toxicity, hematological abnormality, skin eruption, and other symptoms. However, eosinophilic pleural effusion is rare. Thus, we report on a patient with peripheral eosinophilia and eosinophilic pleural effusion after taking sulfasalazine for treatment of AS.

• 허재형(경상대학교 의학전문대학원 내과학교실) | Jae hyung Hur
• 조원용(경상대학교 의학전문대학원 내과학교실) | Won-yong Jo
• 홍정민(경상대학교 의학전문대학원 내과학교실) | Jeongmin Hon
• 김지은(영상의학과, 건강과학연구원) | Ji-Eun Kim
• 서영선(경상대학교 의학전문대학원 내과학교실) | Young Sun Suh
• 이상일(경상대학교 의학전문대학원 내과학교실, 건강과학연구원) | Sang-Il Lee
• 김현옥(경상대학교 의학전문대학원 내과학교실, 건강과학연구원) | Hyun-Ok Kim
• 남대철(정형외과, 건강과학연구원) | Dae Cheol Nam Corresponding author