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HPLC를 이용한 건강기능식품 중 코엔자임 Q10 성분 분석 KCI 등재

Analysis of coenzyme Q10 in dietary supplement by HPLC

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한국식품위생안전성학회지 (Journal of Food Hygiene and Safety)
한국식품위생안전성학회 (Korean Society of Food Hygiene and Safety)
초록

A method based on high-performance liquid chromatography (HPLC) with ultraviolet detection has been developed to quantify coenzyme Q10 (CoQ10) in raw materials and dietary supplements. Single-laboratory validation has been performed on the method to determine linearity, selectivity, accuracy, limits of quantification (LOQ) and repeatability for CoQ10. An excellent linearity (r = 0.999) was observed for CoQ10 in the concentration range 15.625~500 μg/mL in dietary supplement. Observed recovery of CoQ10 was found to be between 98.33 and 99.38%. LOQ was found to be 250 μg/mL Repeatability precision for CoQ10 was between 0.15 and 0.21% relative standard deviation (RSD). Further, limited studies showed that some adulterants and degraded material could be satisfactorily separated from CoQ10 and identified.

저자
  • 노기미(식품의약품안전청)
  • 임동길(식품의약품안전청)
  • 김미경(식품의약품안전청)
  • 박경식(식품의약품안전청)
  • 윤태형(식품의약품안전청)
  • 홍진(식품의약품안전청)
  • 박선영(식품의약품안전청)
  • 정자영(식품의약품안전청)