목적 : 본 연구는 보행이 가능한 편마비 장애인의 가정환경수정 중재 자료로 활용될 지침을 개발하고자 실시하였다. 연구방법 : 전문가 5명을 대상으로 델파이 연구를 시행하였다. 1차 조사는 모두 개방형 질문을 사용하여 실시하였고, 2차 조사는 1차 조사 결과와 선행 연구를 기본으로 하여 조사도구를 만들어 실시하였으며, 4점 척도의 폐쇄형 질문을 사용하였다. 3차 조사는 본인의 의견에 대해 수정할 수 있는 기회를 제공하였다. 결과 : 연구 결과 내용 타당도 지수(content validity index; CVI) 최소값 0.78점 미만 및 수렴도 0.50점 초과인 31개의 항목을 제외하고, 총 96개의 항목을 지침으로 선정하였다. 이는 각 항목의 내용을 요소로 나누었을 때, 기능적 지원성은 49개, 이동과 출입의 용이성은 34개, 접근성은 23개, 공간의 기능과 효율성은 9개로 나타났다. 결론 : 본 지침은 가정환경수정 중재를 실시할 때 필요한 구체적인 내용을 포함하고 있으므로, 지역사회작업치료에서 활용할 수 있을 것이다.

This study intented to standardize the method for total polysaccharide, which is a functional marker for aloe vera gel in Korea. We used four lyophilized raw materials and commercial aloe gel products, certified as Health Functional Food by Korea Food and Drug Administration, including powder, solution, jelly, tablet and capsule, to optimize the analytical condition of dialysis and phenol-sulfuric acid reaction in polysaccharide analysis. The optimal conditions for polysaccharide analysis included 1 L water for dialysis and change 3 times for 24hr against 25 mL prepared sample solution. Validation test showed lower than 5% of coefficient of variation(CV) in intra-, interday validation in lyophilized raw materials and 4 types of commercial products. In inter-person and inter-laboratory validation with 4 persons from 4 different laboratories, CV(%) were 5.50 and 6.64 respectively. The linearity of polysaccharide analysis was assessed using 5 serial concentration of lyophilized raw materials(0.1, 0.2, 0.3, 0.4, 0.5%(w/v)). The results showed R2 ≥ 0.995 of high linearity. In the commercial aloe vera gel products, the results of reproductivity showed lower than 7.08% and revealed that the standardized method from this study ensured high precision for polysaccharide analysis.

One of the most important objectives of post-marketing monitoring of dietary supplements is the early detection of unknown and unexpected adverse events (AEs). Several causality algorithms, such as the Naranjo scale, the RUCAM scale, and the M&V scale are available for the estimation of the likelihood of causation between a product and an AE. Based on the existing algorithms, the Korea Food & Drug Administration has developed a new algorithm tool to reflect the characteristics of dietary supplements in the causality analysis. However, additional work will be required to confirm if the newly developed algorithm tool has reasonable sensitivity and not to generate an unacceptable number of false positives signals.

A method based on high-performance liquid chromatography (HPLC) with ultraviolet detection has been developed to quantify coenzyme Q10 (CoQ10) in raw materials and dietary supplements. Single-laboratory validation has been performed on the method to determine linearity, selectivity, accuracy, limits of quantification (LOQ) and repeatability for CoQ10. An excellent linearity (r = 0.999) was observed for CoQ10 in the concentration range 15.625~500 μg/mL in dietary supplement. Observed recovery of CoQ10 was found to be between 98.33 and 99.38%. LOQ was found to be 250 μg/mL Repeatability precision for CoQ10 was between 0.15 and 0.21% relative standard deviation (RSD). Further, limited studies showed that some adulterants and degraded material could be satisfactorily separated from CoQ10 and identified.

The compulsory beef labelling system has launched from January 1st 2007 by the amended Food Hygiene Law, we were checked the actual conditions of beef origin with a nationwide scale by the Hanwoo differentiation specific test method which was developed by Korea FDA using 90 SNP biomarkers. The test method is useful tool to differentiate the beef origin carrying out the mission of KFDA's annual food safety management guidance. Also we have technically transferred the Hanwoo differentiation specific test method to other institutes as well regional KFDA and established the training program as a regular course in Korea Human Resource Development Institute for Health and Welfare. The beef used in this study were collected according to the 2009 Food safety guidance in roast beef restaurants where business site area greater than 100 m2. Total 216 samples were consisted of 48samples of the Seoul area and 168 of the region. The monitoring result from restaurants in all the region of Korea showed that 3 of 216 Hanwoo-labelled beefs were found out as a non-Hanwoo (1.3%). This results are gradually deceasing trend compared with 34.0% in 2005, 30.1% in 2006, 3.2% in 2007 and 5.14% in 2008. From these data, the Hanwoo differentiation specific test method on the settlement of the compulsory beef labelling system has an important role. As a outcome of this project, we might be considered the early settlement of the compulsory beef labelling system, technically transferred to other institutes and the establishment of regular training program of the test method.

It has been elucidated desmethylsibutramine in food, that is an analogue of sibutramine used for anti-obesity drug. After separating and purifying in food samples, it was analyzed and identified by the instrument such as HPLC/PDA, HPLC/MS, HPLC/MS/MS and NMR. To analyze sibutamine and desmathylsibutramine in foods, they were analyzed and identified by HPLC/PDA after extracting in dichloromethane, filtering, concentration and diluting in methanol. The overall recoveries were ranged from 87% to 91% and the limit of quantitation was 2.5 μg/kg. As results, sibutramine and desmethylsibutramine was not detected in all the selected 54 food samples.

The purpose of this study was to assess the level of quality of life and related factors among the elderly in Korea. In particular, we focused on factors affecting the quality of life of the elderly in long term care. We used the third Korean National Health and Nutrition Examination Surveys (KNHANES) from 2005. We sampled a total of 3,571 (10.5%) elderly from the national survey. We compared the mean of quality of life to socioeconomic status, Activities of Daily Living (ADL), health behavior, and disease variables. We used EuroQol-5D among KNHANES to assess the quality of life. In this study, the mean score of the quality of life among the elderly was 2.57. Logistic regression showed that the elderly who were male, with spouses, with health insurance, and with good ADL levels enjoyed higher quality of life scores and odds ratios than those who were female, divorced, uninsured, and with low ADL levels (p<.05). The quality of life of the elderly was affected by socioeconomic, ADL, health behavior and disease variables. To improve long term care and the quality of life among the elderly, we need detailed research to clarify the effects of these factors.

The aim of the study was to analyze the relationship between empowerment, job satisfaction, and organizational commitment among physical therapists. Currently, healthcare is changing very rapidly with developments in science and technology. In response to these rapid and uncontrollable changes, organizational members are often empowered. Through the empowerment process, feelings of powerlessness and frustration can be reduced and factors promoting work performance, such as job satisfaction and organizational commitment could be enhanced. One said this term popularly, there was a lack of study. There have been few studies on physical therapy administration. Data was collected from 352 therapists from many hospitals from February 1 to February 28, 2008, and analysis of variance, Pearson's correlation, etc., were performed. The results were as follows: Of all the characteristics of empowered subjects, gender (p<.05) and age were observed to be significantly different (p<.01). Educational background, working pattern, marriage status, and the period of duty were observed to be different among empowered therapists (p<.001). The degree of empowerment as perceived by therapists was 58.72. Empowerment was correlated with job satisfaction and organizational commitment (p<.01). The study on empowerment was significant from the aspect of strategies to increase work performance. To elucidate the optimal strategy to effectuate empowerment in clinical practice, we studied various aspects of empowerment. Further studies on the relationship between empowerment and organizational commitment are warranted.

1960년대부터 우리나라는 증가하는 용수수요에 대한 안정적인 생·공용수 공급, 수력발전, 하천생태계 유지를 위한 하천유지용수 공급 및 하천 연안지역의 홍수피해 경감 등의 목적으로 댐 사업이 본격적으로 시작되었다. 그러나 현재 댐 건설적지의 감소, 환경보전에 대한 인식 증대, 지가 상승에 따른 보상비 증가, 지역 주민의 반대 등으로 신규댐 건설에 한계가 있는 실정이다. 이에 대한 대안으로 지하수 이용, 해수의 담수화 등의 대체수자원 개발과 함께 기존 댐의 연계운영에 의한 효율성 극대화 및 기존 댐을 최대한 활용하는 재개발 방안의 필요성이 대두되고 있다. 한정된 자원과 인력을 통해 댐 재개발의 효과를 극대화하기 위해서는 댐 재개발 우선순위 결정이 필수적이다. 따라서 우선순위 결정에 위험성, 경제성, 정책 및 환경성의 사항들을 반영하여 각 사항을 정량화하고, 댐 재개발의 우선순위를 결정하는 방안을 모색해야한다. 현재 국민의 정부와 참여정부에 들어 의사결정 시스템의 개방과 참여자의 다양성으로 인해 공공사업의 투자우선순위를 결정하는 방법이나 과정이 날로 복잡해지고 있다. 본 연구에서는 국내 댐 현황 및 제원 조사를 통해 기초자료 수집을 실시하고, 댐 재개발 우선수위 평가기준 개발을 위한 국내 사례 분석을 통해 기존의 댐 재개발 우선순위 결정 기술에서 나아가 기후변화 및 시대적·환경적 측면을 고려한 다기준 댐 재개발 우선순위를 개발하여 향후 기후변화 적응 댐 재개발 실행 프레임워크 구축 기술에 활용하고자 한다.