The purpose of this study was to assess the effects of Cordyceps militaris extract supplementation on the improvement of blood glucose, lipid compositions and hepatic functional enzyme activities in the serum of streptozotocin(STZ, 50 mg/kg BW, IP injection)-induced diabetic rats fed the experimental diets for 5 weeks. The concentrations of blood glucose and lipid compositions(total cholesterol, β-lipoprotein, free cholesterol, cholesteryl ester, triglyceride and phospholipid) and atherosclerotic index in serum were significantly lower in the DM+CM group than in the DM group, whereas the ratio of HDL-cholesterol concentration to total cholesterol in the DM+CM group were higher than in the DM group.
The activities of hepatic functional enzymes(aminotransferase, LDH and ALP) in serum were lower in the Cordyceps militaris extract administration group(group DM+CM) than in the hyperglycemic DM group. The results shown above suggested that Cordyceps militaris extract supplementation effectively improves blood glucose and atherosclerosis in the serum of diabetic rats.

Abstract
 1. 서 론
 2. 재료 및 방법
  2.1. 실험 재료의 조제
  2.2. 실험동물
  2.3. 식이조성 및 실험군
  2.4. 실험동물의 처치
  2.5. 혈당 농도의 정량
  2.6. 지질성분의 농도
  2.7. 효소 활성의 측정
  2.8. 통계처리
 3. 결과 및 고찰
  3.1. 혈당 농도
  3.2. 혈청 중의 지질성분 농도 및 동맥경화 지수
  3.3. 혈청 중 aminotransferase (AST, ALT)의 활성
  3.4. 혈청 중 lactate dehydrogenase (LDH)의 활성
  3.5. 혈청 중 alkaline phosphatase (ALP)의 활성
 4. 결 론
 참 고 문 헌

• 김한수(부산대학교 식품공학과) | Han-Soo Kim (Department of Food Science & Technology, Pusan National University)
• 김민아(부산대학교 식품공학과) | Min-A Kim (Department of Food Science & Technology, Pusan National University)
• 장성호(부산대학교 바이오환경에너지학과) | Seong-Ho Jang (Department of Bioenviromental Energy, Pusan National University) Corresponding author
• 강동수(전남대학교 식품공학․영양학부) | Dong-Soo Kang (Division of Food Technology & Nutrition, Chonnam National University)
• 이원기(부경대학교 고분자공학과) | Won-Ki Lee (Department of Polymer Engineering, Pukyung National University)
• 류재용(한국원자력연구원 공업환경연구부) | Jae-Young Ryu (Division for Industrial & Environmental Research, Korea Atomic Energy Research Institute (KAERI))
• 이춘식(경남과학기술대학교 환경공학과) | Chun-Sik Lee (Department of Env. Eng., Gyeongnam National University of science and Technology)