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우엉뿌리의 추출조건별 항산화 활성 및 지표물질 함량 분석

Analysis of Standard Compound Contents and Antioxidant Activities of Arctium lappa L. Roots Extracts in Different Conditions

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  • URLhttps://db.koreascholar.com/Article/Detail/362896
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한국약용작물학회 (The Korean Society of Medicinal Crop Science)
초록

Background : Arctium lappa L., Compositae plant, has been consumed as a vegetable and beverage in China, Taiwan, and Japan for a long time. Several studies have reported for the burdock to include antioxidant activity, hepato-protective efficacy, anti-inflammatory activity, anti-proliferative and apoptotic effects, anti-microbial and antiviral activity. Thus, A. lappa is considered a promising plant for the treatment of chronic diseases, such as cancer, diabetes, and AIDS and due to the increasing evidence of functional compounds contributions over a variety of health beneficial properties the A. lappa has received increasing scientific interest. The primary aim of the present study was determined antioxidant activities and analysis of standard compound in A. lappa.
Methods and Results : There were five different solvent conditions (100% water, 30% EtOH, 50% EtOH, 70% EtOH, 100% EtOH), extract in the room temperature. Comparatively, 70% EtOH extract showed higher values of DPPH radical scavenging activity than others. As the increasing of EtOH percentage contents, we confirmed increase total phenol and flavonoid contents. The 2,4-di-tert- butylphenol as standard compound was detected by HPLC analysis based on the calibration curve: equation : Y = 8.17e + 003X – 1.43e + 005, R2 = 0.996227. The amount of standard compounds were similar in all each different solvent conditions, but not detected in water extract.
Conclusion : These results showed that A. lappa could be used as potential materials of antioxidant, and should be need more study.

저자
  • 최수영(강원대학교 생물자원과학과) | Soo Young Choi
  • 박주희(강원대학교 생물자원과학과) | Ju Hee Park
  • 유지혜(강원대학교 한방바이오연구소) | Ji Hye Yoo
  • 유남호(강원대학교 생물자원과학과) | Nam Ho Yoo
  • 박병준(강원대학교 생물자원과학과) | Byung Jun Park
  • 최민우(강원대학교 생물자원과학과) | Min Woo Choi
  • 손순기((주)한산에프앤지) | Soon Ki Son
  • 김태영((주)한산에프앤지) | Tae Young Kim
  • 김명조(강원대학교 생물자원과학과) | Myong Jo Kim Corresponding author