논문 상세보기
pp.769-773
녹차종자를 기능성 식품소재로서 이용하기 위하여 녹차 종자메탄올추출물의 생리활성을 녹차 메탄올추출물의 생리활성과 비교하였다. 녹차 메탄올추출물기 수소공여능은 농도 이상에서 50% 이상의 활성을 나타내었으나, 녹차종자 메탄올추출물은 농도에서 21.86%의 활성을 나타내었다. 또한 녹차종자 및 녹차 메탄올추출물이 농도로 처리된 흰쥐의 간 균질물에서 MDA의 생성량이 대조구의 86 Mol/g에 비하여 각각 60 및 50 Mol/g로 낮게 나타내어
This study was to investigate the biological activities of green tea seed methanol extract (GTSME) and compared those of green tea methanol extract (GTME) for using green tea seed as the functional food material. The hydrogen-donating activity of GTSME was over 50% at the concentration the activity of GTME was 21.86% at the concentration compared with that of control. The MDA (malondialdehyde) production was 60 Mol/g and 50 Mol/g in the mouse liver homogenate teated with GTME and GTSME of concentrations, respectively, and the values were lower than 86 Mol/g of control. GTME and GTSME of concentration inhibited the proliferation of over 50% and over 20% in A549 and SW480 human cancer cells, respectively. The morphology transformation was shown in the cancer cells treated with GTSME of with the decrease of cell numbers lower than that of control cells numbers. The NO production was increased in a dose dependent manner in the RAW264.7 macrophage cells treated with GTME and GTSME of 1, 10, 100 and concentrations, and the NO production by GTSME was at concentration, and the value was higher than by GTME.
