초미세 분쇄법은 식품의 가공방법 중 하나로 특히 이를 이용하여 음용으로 활용범위를 넓힐 수 있다. 본 연구는 이에 착안하여 감을 이용한 초미세 분말을 이용하여 항산화 활성과 자가면역질환인 아토피에 효과가 있는지를 확인하여 보았다. 감 초미세 분말을 이용하여 DPPH와 FRAP 항산화 활성 실험을 수행 하였으며, 마우스 동물모델을 이용한 항알러지 피부염 동물모델을 이용하여 확인하였다. 항산화 활성 실험 결과 감 초미세 추출물은 농도에 따른 활성 등
Ultra-fine powder (FA) extracts from persimmon were investigated as potential food materials in industrial processes because such extracts have various useful biological activities. We examined the antioxidant and anti-allergic activity of FA extracts using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and ferric reducing activity of plasma (FRAP) models, and by measuring interleukin 4 (IL-4) expression in spleen cells and in an atopy animal model. FA extracts were prepared using solvents including distilled water and 50% (v/v) acetone. The results showed that FA extracts had potent DPPH and FRAP activities, decreased IL-4 expression in spleen cells, and inhibited ear thickness and inflammation in a mouse animal model. The data indicate that a FA extract could be used as an antioxidant and/or anti-inflammation agent, and in industrial food preparation processes.