As increased the cultivating areas of several minor crops for medicine such as Glycyrrhiza uralensis, Astragalus membranaceus, Taraxacum platycarpum, Gynanchum wilfordii, and Purple granadilla, the occurrence of major pests and their damages were severed. Primarily occurred pests on five minor crops were observed small in size pests such as whiteflies, aphids and thrips, but the other pests are insignificantly infest. Whiteflies showed higher density in G. uralensis but its damage was insignificant level. Aphids were showed higher density at June in all minor crops and then sharply decreased the density with lower degree of damage. The high damage on initial growth stage will be judge to affect on the yield. Thrips on T. platycarpum showed higher density with 44.1%, compare to other crops, sharply increased the density in late-June and optimal peak in mid-July and decreased in late-Aug. Conclusively, major pests on crops, green peach aphid, mites species on A. membranaceus and G. uralensis, olender aphid, mites species and thrips on G. wilfordii were damaged. Detailed investigation and analysis for economic value of the damaged pest for the continual production will be promoted and then followed the procedure the registration of agrochemicals.

The bird cherry-oat aphid Rhopalosiphum padi (Linnaeus) (Hemiptera: Aphididae) is a polyphagous species and worldwide distribution. We investigated the development periods and survivorship of R. padi nymph, and longevity and fecundity of R. padi adult. The study was conducted at six constant temperatures of 10.0, 15.0, 20.0, 25, 30.0, and 32.5°C, respectively. R. padi developed successfully from nymph to adult stage at all temperatures tested. Developmental rate of R. padi increased as temperature increased from 10.0 to 25.0°C and declined after then. The lower developmental threshold (LDT) and thermal constant (K) of R. padi nymph stage were estimated by linear regression. Higher temperature threshold (TH) and lower temperature threshold (TL) were calculated by two nonlinear functions. LDT and K of R. padi nymph stage were 5.61°C and 100.65DD. The temperature range of R. padi from TL to TH using empirical model (32.18) was wider than that from biophysiological model (27.08). Developmental completion of R. padi nymph stage was described using a two-parameter Weibull distribution model. The adult emergence frequency of R. padi over full range of constant temperatures was simulated using developmental rate functions and Weibull function. Daily egg production of R. padi in relation to adult age and temperature was estimated. Life table parameters were estimated by the jackknife method.

Alzheimer’s disease (AD) is an age-related neurodegenerative disease characterized by extensive loss of synaptic connections, neuronal death, and the presence of extracellular amyloid plaques and intracellular neurofibrillary tangles (iNFTs). The extracellular amlyoid plaques are mainly composed of the amyloid beta (Aβ) peptide which formed by proteolytic processing of the amyloid precursor protein (APP). Aβ42peptide oligomerizes, is neurotoxic and readily forms aggregates that accumulate in the brain to form plaques. These oligomers are thought to cause inflammation, oxidative stress and apoptosis, thereby resulting in synaptic and neuronal loss. Although AD is neurodegenerative disorder, current therapies designed to treat it still demonstrate limited efficacy. Silkworm (Bombyx mori) has long been used as food and medicine in Asian countries which is reputed for the treatment of numerous neurological disorders including AD. In this study, we use Drosophila melanogaster which is expressed the human AD-associated protein APP695, BACE and MAPT as the model and initially investigate whether silkworm powder food has positive effect on flies expressing Alzheimer’s status as well as makes the improvement in disease condition by using this AD fly model (This work was carried out with the support of the Cooperative Research Program for Agriculture Science & Technology Development (Project title: Elucidation the health improvement effects of boiled silk worm larvae, Project No: PJ01082801) Rural Development Administration)

The human β-amyloid (Aβ) cleaving enzyme (BACE-1) is a target for Alzheimer’s disease (AD) treatments. This study was conducted to determine if acacetin extracted from the whole Agastache rugosa plants had anti-BACE-1 and behavioral activities in Drosophila AD models and to determine acacetin’s mechanism of action. Acacetin (100, 300, and 500 μM) rescued amyloid precursor protein (APP)/BACE1-expressing flies and kept them from developing both eye morphology (dark deposits, ommatidial collapse and fusion, and the absence of ommatidial bristles) and behavioral (motor abnormalities) defects. The RT-PCR and Western blot analysis revealed that the protective effect of acacetin on Aβ production is mediated by transcriptional regulation of BACE-1 and APP, resulting in decreased APP protein expression and BACE-1 activity, and reduced Aβ production by interfering with BACE-1 activity and APP synthesis, resulting in a decrease in the levels of the APP carboxy terminal fragments and the APP intracellular domain, and finally, resulting in a decrease in the number of amyloid plaques.

Aedes aegypti and Aedes albopictus and Culex pipiens pallens mosquitoes transmit dengue fever and West Nile virus diseases, respectively. This study was conducted to determine the toxicity and mechanism of action of four flavonoids and seven fatty acids from Millettia pinnata (Fabaceae) seed as well as four fatty acid esters toward third instar larvae from insecticide-susceptible C. p. pallens and A. aegypti as well as wild A. albopictus. Potent toxicity was produced by karanjin, oleic acid, karanjachromene, linoleic acid, linolenic acid, pongamol, pongarotene, and elaidic acid toward C. p. pallens larvae (24 h LC50, 14.61–28.22 mg/L) and A. aegypti larvae (16.13–37.61 mg/L). Against wild A. albopictus larvae, oleic acid (LC50, 18.79 mg/L) and karanjin (35.26 mg/L) exhibited potent toxicity. Acetylcholinesterase (AChE) is the main site of action of the flavonoids, oleic acid, and palmitic acid.,Linoleic acid and linolenic acid might act on both AChE and octopaminergic receptor. Further studies will warrant possible applications of M. pinnata seed-derived products as potential larvicides for the control of mosquito populations.

This paper analyzes the location, landscape elements, and outdoor space composition in the Korean Sosu seowon and Chinese Bailudong seowon. The Sosu and Bailudong seowons were designed to fit well into similar valleys, and they share the approach of Jwa hak woo myo, which means the sacrificial space is on the right and the educational space is on the left. The two seowons each have unique layout characteristics, which reflect topographical features. In the case of the Sosu seowon, the buildings have different orientations, creating a natural arrangement of structures. By contrast, in Bailudong seowon, buildings have a fixed orientation and a formal serial-parallel arrangement along five abscissa axes and one longitudinal axis. Pedestrian systems were established in both seowons, designed to reflect the hierarchical order of the buildings. The Sosu seowon adopted the pedestrian system that encouraged strolling, while the Bailudong seowon’s orthogonal circulation system was set up lengthwise, in parallel with the transverse. The component buildings used for worshiping ancestors and giving lectures, as well as the supporting spaces, were created at the start of the building process, while various other buildings were built to meet the needs of later periods. The two waterscape facilities are also very different: the Takcheongji (pond) at the Sosu seowon symbolizes clarifying the mind through study, while the Panchi (pond) at the Bailudong seowon merges with the Lishengdian (shrine) to contain and represent Confucian culture. The rock carvings at the two seowons differ in both quantity and content. However both sets of rock carvings incorporate Neo-Confucian meanings designed to encourage students to cultivate themselves. From the perspective of earlier literature, both seowons took the meaning of trees very seriously, although they planted different types of trees in their grounds.

Waste treatment technology for the separation and solidification of radioactive nuclides generated from the pyrochemical process has been intensively studied to achieve the reduction of radioactive waste volume. The present study reports the separation efficiency of group II fission products in LiCl waste salt generated from a electrolytic reduction process through a layer- melt crystallization method using Sr and Ba nuclides as a surrogate material of group II fission products. The concentrated group II nuclides are converted into stable oxide form in consideration of solidification by a conversion/distillation process, where selective oxidation of group II nuclides proceeds by Li2O oxidant and residual salts are removed by a vacuum distillation process. Finally, to immobilize separated group II nuclides, a preliminary solidification study was conducted using SiO2-B2O3-Al2O3 matrix, and high density glass-based waste form was fabricated under 50wt% waste loading of strontium oxide surrogate material. Through the verification of the crystallization, conversion/distillation, and solidification processes, the treatment flow for the separation and solidification of group II fission products in LiCl waste salt has been established.