The present case occurred in the cervical area of 51 years old male, who was generally healthy but recently complained of cervical swelling with mild pain. The tumor recently grew rapidly for 5 months. He was referred from local hospital in the diagnosis of metastatic tumor in cervical lymph. In the biopsy procedure, the tumor mass was ill-defined and not associated with cervical lymph node. The microsection showed a highly proliferative fibrous tissue infiltrative growth into the periphery. The spindle tumor cells were stained red in Masson trichrome stain, and strongly positive for PCNA and β-catenine, and partly positive for α-smooth muscle actin (α-SMA), but negative for S-100 and desmin. The differential diagnosis in primary biopsy examination was made as leiomyosarcoma, malignant schwannoma, and mesenchymal sarcoma. Under the diagnosis of sarcoma the patient was operated for tumor resection including cervical lymph nodes. The tumor mass was tightly attached on the lower border of left mandibular body. After the surgical operation the tumor tissue was more investigated with further immunohistochemical stainings, and discussed with several pathologists in Gangneung area. Finally the tumor was turned out to be a nodular fasciitis with pseudosarcomatous proliferation, and also confirmed that the pseudosarcomatous spindle cells belonged to the myofibroblasts originated from the fibrovascular fascial tissue. The present study demonstrated a rare case of nodular fasciitis, which should be differentially diagnosed from the malignant head and neck tumors.

The purpose of this study was to observe the histopathologic reaction in vital bone to various surface treated implants. For this purpose, ten New Zealand Albino rabbits, weighing 3.3 to 4kg were used as experimental animals. All the experimental groups divided into five groups; 1) Machined surface as control, 2) RBM(resorbable blast media), 3) RBM etched nitric acid solution, 4) RBM etched sodium hydroxide solution, 5) RBM etched acid, alkali, and heat treated group on each. All the surfaces of implants were examined under the scannning electron microscope to distinguish the differences between each experimental groups compare to that on the control group. All the rabbits were implanted into the tibial metaphyses of rabbits. On the 4th and 8th week after implantations, all the experimental rabbits were sacrificed. All the tissues containing each implanted materials were fixed in ethyl alcohol, and embedded in spurr resin as usual manner, sectioned in 10μm or more thickness, grinded, stained with the Villanuevaʼs osteochrome bone stain method and examined histopatholgically. For the fluorescence microscopic examination, three kind of fluorescence dyes, Oxytetracycline, Alizarin-Complexone, and Xylenol-Orange were injected to put into the bone to implant interface produced polychromatic fluorescence labelling on the 1st week, 2nd week, and 5th week on each. On the 8th week after experiments, the animals sacrificed, and the tissues containing the implants were taken, fixed in ethyl alcohol and embedded in spurr resin, sectioned, grounded 10um in thickness and examined under the fluorescence microscope. Following results were obtained; On the scanning electron microscopic examination of the implants, dull cracks, continuous linear indentations were revealed on the machined surface implant, irregular multiple leaflike eruptions on the RBM, and more sharp porous indentation with multiple complicated c rack s on the RBM acid etched surface, and more dull margins on complicated porous indentation on the RBM alkalic etched surface and more dull and less indented particles were noted on the RBM, acid, alkalic etched, heat treated surface, On the histopathologic examination, on the 4th week after experiment, complete osseointegation was noted between the implant and cortical bone on the collar and the apex lesion. and in parts, small newly formed bone spicules directly attached to the screws, and osteoid tissues were revealed in marrow tissues, in all experimental groups. On the histopathologic examination, on the 8th week after experiment, osseointegration is more increased compare to that on the 4th week group, the amount of bone trabeculae and osteoid tissues directly fused to screw of implants were markedly increased. On fluorescence examination, band or linear shape was witnessed on the boarder of compact bone and marrow tissues, and on bone trabeculae according to the formed age. and precipitated as granular and globular shape on the haversian canals. These results indicate that the surface treated method used for the present study render the implants compatible to bone tissue but the tissue compartibility is not different among the surface treated implants.

The purpose of this study was to evaluate the role of c-fos and c-jun expression in the odontogenic cysts. For this study, 20 subjects of odontoenic dysts: 8 subjects of keratocysts and 12 subjects of periodontal cysts referred to the Dept. of Oral Pathology, School of Dentistry, Kyung Hee University, were used as experimental group, and 5 subjects of normal oral mucosa without any inflammatory changes. were used as control groups respectively. All the tissues of experimental and control group were fixed in neutral formalin solution and embedded in paraffin, serial tissue section were made 5㎛ in thickness and processed in the standard way for immunohistochemical method, using primary antibodies, for c-fos, c-jun was diluted at 1:100 each, followed by the super sensitive non-biotin horse radish peroxidase system with DAB as chromogen application, counter stained with Gill's hematoxylin stainmethod, mounted. And examined under the biologic microscope with the criteria of -(no epithelial stain), +(weak or focal epithelial stain), ++(moderate or focal intensive epithelial stain), +++(intense generalized epithelial staining) for the epithelial, and stromal tissues on each. Attained results as follows. In normal oral mucosa, it is noted that moderate positive responses in cytoplasm and nuclei to c-fos and c-jun protein on each.. In the responses to c-fos, c-jun protein, moderate positive responses in nuclei and cytoplasms of the epithelial lining in keratocysts and periodontal cysts, but more intense reaction is noted on the periodontal cyst compare to that on the keratocysts. In the responses to c-fos, c-jun, it is noted that more intense responses in odontogenic cyst compare to that in the oral mucosa. In the responses to c-fos and c-jun on submucoas of oral normal mucosa, focal epithelial stain was noted. and more intensive reaction was noted on the odontogenic cysts, most in periodontal cysts. This results suggests that c-fos and c-jun protein effected on the induction of development and growth of the cysts