The epidemiology of reported food-borne disease (FBD) outbreaks from 2001 to 2008 in Korea and Japan were compared in this study. The outbreak rate of FBD in Japan was significantly higher although the average number of patient in each outbreak in Korea was much higher. In both countries, summer was the season when most FBD outbreaks occurred. The comparison study revealed that FBD outbreaks in spring were more frequent in Korea, and outbreaks in winter were more frequent in Japan. Almost half of FBD outbreaks were observed at restaurants in both countries while FBD outbreaks at schools and work-places in Korea were much higher than in Japan. The most frequent cause of bacterial FBDs in Korea was pathogenic Escherichia coli followed by Salmonella species. On the other hand, Campylobacter jejuni was the most frequent source of bacterial FBDs in Japan. Norovirus, which is related to uncontrolled hand hygiene and involvement of ill food workers, was the main cause of viral FBDs in both countries. In conclusion, there are common epidemiological characteristics as well as several differences in FBD outbreaks of Korea and Japan. These are suggested to be originated from the characteristic of climate, food sources, and life styles in two countries. Establishment of stricter control and surveillance system for FBD outbreaks are required for prevention and reduction of FBD outbreaks in both countries.

흰쥐의 체중은 실험기간 동안 증가하였으며, 식이별로는 대조군이 가장 높은 체중 증가를 보였다. 콜레스테롤의 첨가는 흰쥐의 정상적인 성장을 억제하였으며, 콜레스테롤 첨가군에서는 콜레스터롤 대조군의 체중증가량이 유의하게 가장 낮았다. Rutin과 메밀채소를 식이에 첨가하였을 때 흰쥐의 콜레스테롤에 의한 성장억제 작용을 효과적으로 감소시키는 것으로 나타났으며, 첨가량의 증가에 따라 헐청에 총콜레스테롤 함량과 과산화지질 함량은 낮아진 반면에 HDL-cholesterol 함량은 높아지는 경향을 보였다. 고콜레스테롤 식이를 급여시킨 흰쥐의 장기에서는 칼슘침착이 나타나는 병리조직학적 변화를 보였으며, 메밀채소 섭취에 의하여 칼슘침착의 정도는 완화되었다.