기존의 “비트매니아”와 같은 리듬게임은 게임 개발자가 해당 음악의 악보에 맞게 노트를 생성하여 사용자가 정확히 연주 할수록 좋은 결과가 나오도록 구현되어 있다. 하지만 선택할 수 있는 노래가 제한되어 있다는 단점이 있다. 따라서 본 논문에서는 사용자가 자신이 원하는 음악을 플레이할 수 있도록 mp3와 같은 디지털 오디오 파일을 FFT 알고리즘을 이용하여 실시간으로 음계를 추출하고 정렬한 뒤 게임 인터페이스 상에 노트를 생성한다. 또한 BPM정보를 이용하여 노트의 생성 순서와 게임의 난이도를 조절한다.

Sea Buckthorn (Hippophae rhamnoides L.) has been used in traditional medicine for the treatment of cough, indigestion, circulatory problems and pain. The associated anti-inflammatory effect of this agent is achieved via the inhibition of Nf-kB signaling, a property that has been demonstrated to effectively control the symptoms of various skin disorders, including atopic dermatitis. Accordingly, the purpose of this study was to assess the efficacy of Sea Buckthorn in reducing the production of lipopolysaccharide (LPS) activated nitric oxide (NO) by inhibiting the Nf-kB pathway, as measured by the symptoms of atopic dermatitis (AD) occurring secondarily to inflammation and immune dysregulation. Our data demonstrate that Sea Buckthorn significantly decreased the LPS-induced production of NO (p〈0.001). Atopic dermatitis was induced by repeated application of 2,4-dinitrochlorobenzene to the dorsal skin of mice. Topical application of 5% Sea Buckthorn extract improved the symptoms of AD, specifically reducing disease severity scores, scratching behaviors and epidermal thickness. When compared to the control group, animals treated with Sea Buckthorn exhibited increased serum IL-12 levels and decreased serum TNF-α, IL-4 and IL-5 levels. Such a modulation of biphasic T-helper (Th)1/Th2 cytokines may result in a reduction in serum IgE levels. Our findings suggest that mechanism of action of Sea Buckthorn in the treatment of AD is associated with a marked anti-inflammatory effect as well as an inhibition of Th2-mediated IgE overproduction via the modulation of biphasic Th1/Th2 cytokines. Such results suggest that topical Sea Buckthorn extract may prove to be a novel therapy for AD symptoms with few side effects.

Growth and yield of licorice were investigated under the different conditions of photoperiod and shading in order to establish its cultural practice for the domestic production with the aim to substitute the import. The photoperiod was adjusted to 8,10, and 12 h by shielding plants from the light with blackout curtain. Large seedlings(11-20g) appeared to be affected by photoperiod since around 65 days. Most of growth parameters, including plant height, number of leaf, fresh and dry weight of plant and root, were the highest in 12 h photoperiod among all the photoperiod levels, excepting stem diameter which was the highest in 10 h photoperiod(4.5mm). Each photoperiod was similar to each other in root length and diameter. Small seedlings(4-l0g) showed a similar trend to large seedlings. The results from field photoperiod experiment demonstrated that 12 h photoperiod was also the best among three photoperiod treatments in plant height, stem diameter, number of leaf, root length, fresh and dry weight of plant and root. The effect of shading was tested under the three levels of control (0%), half-shading (55%), and full shading (90%). Shading remarkably suppressed the growth and yield, compared to no-shading. Although plant height and root length were little affected by the shading, stem and root diameters were heavily reduced.

Growth and yield of licorice were investigated under the different conditions of ridge height, planting density, and irrigation in order to establish its cultural practices for the domestic production with the aim to substitute the import. Seedlings were grown under low ridge(20cm) and high ridge(40cm) in low density plot(60×30cm) and high density plot(40×30cm), respectively. The low ridge cultivation of large seedlings increased plant height and root length under low density, and stem and root diameter under high density compared to the high ridge cultivation. In the high ridge cultivation, high density plot was 1.1 to 1.3 times in plant height, root length, stem and root diameter as high as low density one. Fresh and dry weight of plant and root in high ridge were 1.3 to 1.5 times as high as those in low one. The growth of small seedlings(4~10g) were generally poor compared to that of large seedlings. High density plot in low ridge showed the good growth characteristics including plant height, root length, stem and root diameter, and number of branch. High density plot was 1.4 to 1.6 times in fresh and dry weight of plant and root as high as low density plot. In the seasonal changes of growth under various irrigation regimes, the twice irrigation a day produced the more number of leaf than the other regimes since around 46 days after transplanting. The former irrigation resulted in 1.2 to 1.4 times in plant height as long as the other irrigations around 26 days after transplanting and then the difference was increased to 1.6 to 2.0 times around 64 days after transplanting. Under the twice irrigation a day, plant height, root length, stem diameter, root diameter, number of leaf, fresh plant weight, dry plant weight, fresh root weight, dry root weight were 1.6 to 2.0, 1.1, 1.2 to 1.6, 1.3 to 1.8, 1.9 to 2.7, 1.7 to 8.0, 1.6 to 2.8,2.0 to 3.0, 1.6 to 2.7 times as high as those under the other irrigation regimes, respectively.