Priority should be considered to encourage businesses to participate by activating the low-noise machine certification system. However, the domestic low-noise machine certification system has not yet been significantly activated. There is a need for a system that only products that meet the environmental sign certification standards for low-noise construction machinery are recognized as "low-noise machines". A compliance evaluation agency (CAB) in the field of low-noise equipment should be introduced in Korea to help facilitate international certification of domestic company products. Therefore, it is believed that it will help expand the supply of low-noise machines through technology development and export improvement.

This study investigated the operation status of major construction machines used in domestic construction sites and analyzed the characteristics of noise generated by these machines. In addition, we tried to understand the impact of construction machine noise on the working environment and the surrounding environment. As a result of the analysis, the noise level of the working breaker was the highest at 101.5 dB(A). This suggests that it can act as a major factor in the spread of noise to the residence around the construction site and the occurrence of civil complaints from residents. Therefore, this study is expected to provide a scientific basis for the noise problem of construction machinery and be used as basic data for effective noise management policies and system improvement.

Nicotinamide (NAM), a water-soluble derivative of vitamin B3, has emerged as a potential therapeutic agent for bonerelated disorders. In particular, it promotes bone metabolism and alleviates delayed tooth eruptions associated with cleidocranial dysplasia (CCD). NAM serves as a precursor for nicotinamide adenine dinucleotide, a key coenzyme involved in cellular metabolism that plays an essential role in oxidative phosphorylation and mitochondrial function. Recent research has highlighted the capacity of NAM to enhance osteogenic differentiation and regulate the interaction between osteoblasts and osteoclasts, which is critical for maintaining bone homeostasis. Moreover, the effect of NAM in preventing delayed tooth eruptions in CCD models underscores its potential as a noninvasive therapeutic option. Considering its safety profile and therapeutic potential, NAM is a promising candidate for longterm treatment of bone diseases and prevention of age-related bone disorders.

In this study, an experimental analysis of noise reduction in road traffic by applying the Micro Grooving technique to concrete highway pavements is explored. Initiated in 1984 to address the aging and damage issues observed in South Korea's concrete highways, Micro Grooving is known for creating fine grooves on the cement pavement surface to increase friction, prevent hydroplaning, and inhibit ice formation, while reducing vehicle friction noise by 3∼5dB(A). It is determined from noise measurement results that the application of the Micro Grooving method can be expected to reduce roadside noise and enhance the safety of drivers' driving experience.

Noise is unwanted sound and nerve jarring sound or mentally and physically harmful sound to the human body. In the 20th century, the aviation industry have been comprehensive industry of all areas and humanity have been globalized, the number of aircraft operated have been increased continuously. We confirmed that the actual measured noise data was consistent with the aircraft average noise data to calculate noise maps of INM version 7.0. and based on this, the actual flight scenarios and the noise map were created. For making the noise map, we assumed that the maximum number of flight is operated.

Interferon-stimulated gene 15 (ISG15) is known to interfere with viral replication and infection by limiting the viral infection of cells. Interferon-stimulated gene 15 (ISG15) interferes with viral replication and infectivity by limiting viral infection in cells. It also plays an important role in the immune response. In this study, tissue-specific expression of ISG15 in healthy rock bream samples and spatial and temporal expression analysis of rock bream ISG15 (RbISG15) were performed following rock bream iridovirus (RSIV) infection. RbISG15 expression was significantly higher in the eye, gill, intestine, kidney, liver, muscle, spleen, and stomach, but low in the brain. There were particularly high levels of expression in the liver and muscle. RbISG15 expression was also examined in several tissues and at various times following RSIV infection. ISG15 expression increased within 3 h in the whole body and decreased at 24 h after infection. In addition, temporal expression of several tissues following RSIV infection showed a similar pattern in the muscle, kidney, and spleen, increasing at 3 h and decreasing at 72 h. These results suggest that ISG15 plays an important role in the immune response of rock bream. Overall, this study characterizes the response of RbISG15 following RSIV infection.

Lectins belong to the pattern-recognition receptors (PRRs) class and play important roles in the recognition and elimination of pathogens via the innate immune system. Recently, it was reported that lily-type lectin-1 is involved when a pathogen attacks in the early immune response of fish. However, this study is limited to information that the lectin is involved in the innate immune response against viral infection. In the present study, the lily-type lectin-2 and -3 of Oplegnathus fasciatus (OfLTL-2 and 3) have been presented to be included B-lectin domain and two D-mannose binding sites in the amino acid sequence that an important feature for the fundamental structure. To investigate the functional properties of OfLTLs, the tissue distribution in the healthy rock bream and temporal expression during early developmental stage analysis are performed using quantitative real-time PCR. OfLTL-2 and 3 are predominantly expressed in the liver and skin, but rarely expressed in other organ. Also, the transcripts of OfLTLs are not expressed during the early developmental stage but its transcripts are increased after immune-related organs which are fully formed. In the challenge experiment with RBIV (rock bream iridovirus), the expression of OfLTLs was increased much more strongly in the late response than the early, unlike previously known. These results suggest that OfLTLs are specifically expressed in the immune-related tissues when those organs are fully formed and it can be inferred that the more intensively involved in the second half to the virus infection.