구절초(Chrysanthemum zawadskii var. latilobum (Maxim.) Kitam.)는 linarin, chlorogenic acid 등의 유용성분들을 함유하고 있으며, 산업적으 로 이용가치가 있는 식물이다. 구절초의 산업화를 위해 유용성분인 linarin과 chlorogenic acid의 최적 추출 조건을 구하기 위해 반응표면분석을 수행하였으며, Linarin의 최적 추출 조건은 에탄올 농도 100%, 추출 시간 30h, 추출 온도 75℃였다. 최적 추출 조건에서 예상된 linarin의 값은 33.36 mg/g였으며 실험값은 38.33±2.66 mg/g였다. Chlorogenic acid의 최적 추출 조건은 에탄올 농도 48%, 추출 시간 30h, 추출 온도 65℃로 예상된 chlorogenic acid의 함량은 42.19 mg/g였으며 실험값은 44.34±2.09 mg/g이었다. 반응표면분석법으로 도출된 최적 추출 조건을 통해 구절초에서 linarin과 chlorogenic acid의 효율적인 추출이 가능함을 확인하였다.

This paper presents a path planning optimization model for the engineering units to install obstacles in the shortest time during wartime. In a rapidly changing battlefield environment, engineering units operate various engineering obstacles to fix, bypass, and delay enemy maneuvers, and the success of the operation lies in efficiently planning the obstacle installation path in the shortest time. Existing studies have not reflected the existence of obstacle material storage that should be visited precedence before installing obstacles, and there is a problem that does not fit the reality of the operation in which the installation is continuously carried out on a regional basis. By presenting a Mixed Integrer Programming optimization model reflecting various constraints suitable for the battlefield environment, this study attempted to promote the efficient mission performance of the engineering unit during wartime.

Environmental pollution has led to global warming, which threatens human life. In response, hydrogen is gaining attention as a next-generation energy source that does not emit carbon. Due to its explosive nature, special care must be taken in the safe storage and transportation of hydrogen. Among various storage methods, liquefied storage, which can reduce its volume to 1/800, is considered efficient. However, since its boiling point reaches -253°C, the design of an insulation system is essential. For the design of insulation systems applied to large containers, a membrane-type design is required, which necessitates the use of cryogenic adhesives. To evaluate whether the cryogenic adhesive is properly implemented, assessments such as tensile and shear tests are necessary. This study presents a methodology for shear evaluation. Conventional methods for shear evaluation of adhesives result in slippage, preventing proper assessment. Therefore, a method involving drilling holes in the gripper and pulling from the holes must be applied. Optimal design concerning the size and location of the holes is required, and this study derives optimal values based on finite element analysis. By conducting experiments based on the results of this study, it is expected that the risk of gripper damage will be minimized, allowing for accurate evaluation of the adhesive’s performance.

The design variables and material properties as well as the external loads concerned with structural engineering are used to be deterministic in optimization process. These values, however, have variability from expected performance. Therefore, deterministic optimum designs that are obtained without taking these uncertainty into account could lead to unreliable designs, which necessitates the Reliability-Based Design Optimization(RBDO). RBDO involves an evaluation of probabilistic constraints which constitutes another optimization procedure. So, an expensive computational cost is required. Therefore, how to decrease the computational cost has been an important challenge in the RBDO research field. Approximation models, response surface model and Kriging model, are employed to improve an efficiency of the RBDO.

본 논문에서는 신뢰성 기반 최적설계(RBDO)에서 성능함수의 비선형성을 고려한 효율적인 차원감소법(DRM)을 제안한다. 차원감 소법은 적분직교점과 가중치를 사용하여 1차 신뢰도법(FORM) 보다 더 정확하게 신뢰도를 평가하는 반면 성능함수를 추가로 해석해 야하기 때문에 적분직교점의 개수가 증가하면 효율성이 저해된다. 본 논문에서는 신뢰성 기반 최적설계에서 성능함수의 비선형도를 평가하고, 비선형도에 따라 적분직교점의 수를 결정하는 기준을 제안한다. 이를 통해 신뢰성 기반 최적설계가 진행될 때 반복마다 적 분직교점의 수를 조절하여 차원감소법의 정확도는 유지하면서 계산의 효율성은 개선하는 방안을 제안한다. 성능함수의 비선형도 평 가는 최대가능목표점(MPTP) 탐색에 사용한 벡터 사이의 각도를 통해 이루어지며, 수치 테스트를 통해 비선형도에 따른 적절한 적분 직교점의 수를 도출하였다. 2차원 수치예제를 통해 개발된 방법이 차원감소법이나 몬테카를로 시뮬레이션(MCS)의 정확도는 유지하 면서 효율성이 향상된다는 것을 확인하였다.

This research presented the procedural framework of developing and optimizing an artificial intelligence model for predicting the change of bread texture by different baking enhancers. Emphasis was placed on the impact of various baking enhancers on the Mixolab thermo-mechanical properties of wheat flour and consequent alterations in bread texture. The application of baking enhancers positively contributed to dough formation and stability, producing bread with a soft texture. However, a relatively low Pearson correlation coefficient was observed between a single Mixolab parameter and bread texture (r<0.59). To more accurately predict the texture of bread from the thermo-mechanical features of wheat flour with baking enhancers, five AI models (multiple linear regression, decision tree, stochastic gradient descent, random forest, and multilayer perceptron neural network) were applied, and their prediction performance was compared. The multilayer perceptron neural network model was further utilized to enhance the prediction of bread texture by mitigating overfitting risks. Finally, the hyperparameter tuning (activation function [Leaky ReLU], regularization [0.0001], and dropout [0.1]) led to enhanced model performance (R2 = 0.8109 and RMSE = 0.1096).

The objective of this study was to determine the ultrasonication-assisted extraction conditions that maximize the DPPH radical scavenging activity of extracts obtained from the stems of Lespedeza bicolor Turcz through the application of the Response Surface Methodology (RSM). Before delving into the analysis of extraction conditions using the RSM model, we conducted efficiency validation of ultrasonication-assisted extraction and executed single-factor experiments for ethanol concentration, extraction time, and extraction temperature. The data obtained from these single-factor experiments were employed to construct the Box-Behnken Design (BBD). In these results, in the single-factor experiments, it was evident that the parameters for ethanol concentration, extraction time, and extraction temperature exhibited quadratic trends. The single-factor experiments allowed us to discern the trends for each parameter leading to the maximum antioxidant capacity, and this data was subsequently applied to the BBD. Following the completion of initial experiments, a Response Surface Methodology (RSM) model was constructed based on Box-Behnken Design (BBD). According to the predictive model developed in this study, it was anticipated that performing ultrasonic-assisted extraction for 85.0412 minutes at an ethanol concentration of 32.573% and an extraction temperature of 51.5608°C will result in a DPPH radical scavenging activity of 79.7146%. The predictive results were statistically verified through a comparative analysis with actual measurements and ANOVA analysis, confirming the statistical significance of the model. The finding of this study underscore the significance of optimizing extraction conditions in the precise quantification of the antioxidant potential for economic advantages in both experimental and industrial contexts.

본 연구에서는 수크로스 스테아레이트(SS)의 유화력과 가용화력을 좀 더 향상시키기 위해, sodium deoxycholate (SDOC)와 PEG-40 hydrogenated castor oil (HCO)와의 혼합 조성물을 구성하였 다. 혼합물의 최적 조성을 구하기 위해 혼합물 실험 계획법을 도입하여 실험을 진행하고, 실험에서 얻은 데 이터를 회귀 분석하여 혼합물 조성의 변화가 혼합물의 특성에 미치는 영향을 살펴보았다. SS에 SDOC만을 첨가했을 때 코코넛 오일에 대한 유화력이 가장 향상되고, HCO만을 첨가했을 때는 가용화력이 가장 향상 된 반면, 에스테르 오일인 cetyl ethylhexanoate (CEH)에 대한 유화력은 SDOC와 HCO를 함께 첨가했을 때 가장 크게 향상됨을 알 수 있었다. 코코넛 오일 및 CEH 각각에 대한 유화력과 가용화력, 3개의 특성치 에 대한 동시 최적화를 실시한 결과, 최적의 계면활성제 혼합 조성은 SS 0.7939, SDOC 0.0586, HCO 0.1475로 구해졌다.

The adhesive design of a fast steering mirror transmitting a high power laser is one of the important design elements that affect optical aberration of the mirror surface. In this paper, we designed the adhesive part to avoid the high power laser beam of the FSM system. Stiffness and wavefront error are trade-off relationships and an optical design was derived to maintain the wavefront error of the mirror surface at high temperatures while satisfying the bandwidth of the FSM system. For the optimal design of the mirror bonding position, structural analysis was conducted using ANSYS and wavefront error analysis was performed using Zernike polynomial code. Through those analysis, FSM most effective at an angle 60 degrees and a distance of 46mm.

본 논문에서는 다이나믹크리깅 대리모델 기반 자동차 브레이크 패드 마모량 측정센서 브라켓의 설계최적화를 소개한다. 브레이크 작동시 마찰재 바닥의 온도가 600°C 이상으로 상승하고, 이 열이 전달되어 센서의 기능을 상실시킨다. 따라서 열전달을 최소화하는 브라켓 형상의 설계최적화는 필수적이다. 최적화에 소요되는 계산비용을 절감하기 위해 다이나믹크리깅 대리모델로 열전달 시뮬레 이션을 대체하였다. 다이나믹크리깅은 최적의 상관함수와 기저함수를 선정하였으며, 정확한 대리모델을 도출하였다. 최적화 결과 센 서위치의 온도가 초기모델에 비해 7.57% 감소하였으며, 이를 열전달 시뮬레이션으로 다시 한번 확인하여 대리모델 기반 최적설계가 유의미함을 검증하였다.

본 연구는 그린커피빈추출물이 「건강기능식품의 기준 및 규격」에 추가로 등재될 경우를 대비하여 표준화된 클 로로겐산 시험법을 설정하고, 카페인이 동시 분석되도록 최적화하는 연구를 진행하였다. 최적화된 시험법을 마련 하기 위해 기기분석 및 전처리 조건을 비교·분석하여 클 로로겐산과 카페인을 30% 메탄올 추출하여 인산용액과 인산 함유 아세토니트릴으로 액체크로마토그래프를 통해 330 nm, 280 nm에서 분석하도록 시험법을 설정하였다. 시 험법 밸리데이션 결과, 직선성 정량범위 내에서 상관계수 (R2) 0.999 이상의 유의수준을 보였고, 클로로겐산과 카페 인 검출한계는 0.5와 0.2 μg/mL, 정량한계는 1.4와 0.4 μg/ mL로 나타났다. 정밀도와 정확도 결과는 AOAC 밸리데 이션 가이드라인를 통해 적합함을 확인하였고, 클로로겐 산 및 카페인 동시분석법을 최종적으로 마련하였다. 또한, 시제품과 유통제품을 통해 제형별 적용성 검토하여 클 로로겐산과 카페인을 동시에 정량 가능한 시험법임을 재확인하였다. 최적화된 시험법은 클로로겐산을 함유한 건강기능식품 품질관리에 대한 신뢰성을 더 높일 것으 로 본다.

The optimization of deacetylation process parameters for producing chitosan from isolated chitin shrimp shell waste was investigated using response surface methodology with central composite design (RSM-CCD). Three independent variables viz, NaOH concentration (X1), radiation power (X2), and reaction time (X3) were examined to determine their respective effects on the degree of deacetylation (DD). The DD of chitosan was also calculated using the baseline approach of the Fourier Transform Infrared (FTIR) spectra of the yields. RSM-CCD analysis showed that the optimal chitosan DD value of 96.45 % was obtained at an optimized condition of 63.41 % (w/v) NaOH concentration, 227.28 W radiation power, and 3.34 min deacetylation reaction. The DD was strongly controlled by NaOH concentration, irradiation power, and reaction duration. The coefficients of correlation were 0.257, 0.680, and 0.390, respectively. Because the procedure used microwave radiation absorption, radiation power had a substantial correlation of 0.600~0.800 compared to the two low variables, which were 0.200~0.400. This independently predicted robust quadratic model interaction has been validated for predicting the DD of chitin.

This study is concerned with the optimization of the manufacturing process of a hot water extract containing antioxidant activity from Lycium barbarum, traditionally known to have various physiological activities. For the establishment of the optimization process, the central composite design of response surface methodology(RSM) was used. Thirteen extraction processes were performed by encoding the independent variables, extraction temperature (65.9oC–94.1oC) and extraction time (2.59 hr–5.41 hr). As a result of the experiment, the optimal manufacturing conditions for the extract were 340.0 mg/100 g of GAE at an extraction temperature of 94.1oC and an extraction time of 5 hr. The maximum yield of flavonoids was 22.44 mg/100 g of HES at an extraction temperature of 94.1oC and an extraction time of 4 hr. The conditions for producing the extract with the maximum antioxidant capacity (DPPH 92.12%) were 90oC and 4.5 hr extraction time. Therefore, the optimal manufacturing process conditions for extracts containing total phenol content, flavonoid content, and DPPH radical scavenging activity, which are dependent variables, were extraction temperature of 90-95oC and extraction time of 4 hr, which were not significantly different from the actual values. Therefore, Lycium barbarum extract rich in total phenol and flavonoid content related to antioxidant function is expected to be used as a functional food and cosmetic material.