PURPOSES : In this study, the applicability of the water content, suction, and suction stress in a resilient modulus prediction model for a subbase was reviewed. METHODS : To compare the applicability of water content, suction, and suction stress models for resilient modulus prediction, the suction stress was determined based on the soil water characteristic curve. The model parameters for each approach were derived from the measured resilient moduli. Finally, the relationships between the degree of saturation and resilient modulus were analyzed using the calculated model parameters. RESULTS : Prediction models of the resilient modulus based on water content and suction demonstrated high correlation with measured values, but overestimated the resilient modulus at saturation levels beyond the laboratory testing range. In contrast, the model accounting for suction stress effectively reduced this overestimation, likely owing to a decrease in suction stress as the suction increased. CONCLUSIONS : Based on the above results, the resilient modulus of subbase materials could be estimated through the change in the degree of saturation and the stress-dependent resilient modulus model using the suction stress proposed in this study.

PURPOSES : In this study, an empirical approach was established to estimate the parameters of the resilient modulus based on various geotechnical properties of subgrade soils. METHODS : Multiple regression analyses were performed to analyze the relationship between resilient modulus (k1) and deformation. The most important factors are the #200 sieve passing ratio, moisture content, and dry unit weight of the soil. The applicability of this approach was verified using selected field data and the literature. RESULTS : The correlation between the results predicted using the prediction equation of the model constant (k1) and the actual k1-value was high. The applicability of the prediction equation was considered high owing to its high suitability with the existing data. The range of values obtained using the constant prediction equation of the proposed model was also judged to be reasonable. In the comparison of the CBR value of the subgrade material of the actual design section and the predicted elastic modulus (k1), almost no relationship was observed between the CBR and the model coefficient (k1). Thus, the estimation of the elastic modulus through CBR is likely to contain errors. CONCLUSIONS : Based on these results, the parameters of the universal model can be predicted using the stress-dependent modulus model proposed in this study.

재활용된 암버력-토사의 회복탄성계수 예측모델이 개발되었다. 반복삼축시험을 통한 회복탄성계수의 전통적 평가방법은 큰 입경을 가진 자갈에는 실현 불가능하다. 미세한 차이가 있는 비선형 전단탄성계수를 이용하여 회복탄성계수를 산출하는 대체기법을 제안하였다. 현장에서 측정한 최대전단탄성계수와 대형공진주 시험으로 구한 감소곡선을 이용하여 회복탄성계수 예측모델을 개발하였다. 이 예측모델을 김천의 고속도로공사현장에서 재활용한 암버력-토사에 적용하여 모델인자 AE, nE, εr, α를 각각 9618, 0.47, 0.0135, 0.8로 제안하였다.

Mortality rates from stroke have been declining. Because of this, more people are living with residual disability. Rehabilitation plays an important role in functional recovery of stroke survivors. In stroke rehabilitation, early prediction of the obtainable level of functional recovery is desirable to deliver efficient care, set realistic goals, and provide appropriate discharge planning. The purpose of this study was to identify predictors of functional outcome after stroke using inpatient rehabilitation as measured by Functional Independence Measure (FIM) total scores. Correlation and stepwise multiple regression analyses were performed on data collected retrospectively from two-hundred thirty-five patients. More than moderate correlation was found between FIM total scores at the time of hospital admission and FIM total scores at the time of discharge from the hospital. Significant predictors of FIM at the time of discharge were FIM total scores at the time of hospital admission, age, and onset-admission interval. The equation was as follows: expected discharge FIM total score = 76.12+.62×(admission FIM total score)-.38×(age)-.15×(onset-admission interval). These findings suggest that FIM total scores at the time of hospital admission, age, and onset-admission interval are important determinants of functional outcome.

This study was designed to investigate the effects of treadmill exercise of low-intensity and moderate- intensity on the functional recovery and histological change in spinal cord injury (SCI) rats. SCI was induced by the spinal cord impactor dropped after laminectomy. Experimental groups were divided into the Group I (normal control), Group II (non-treatment after SCI induction), Group III (low-intensity treadmill exercise after SCI induction), Group IV (moderate-intensity treadmill exercise after SCI induction). After operation, rats were tested at modified Tarlov scale at 2 days with divided into 4 groups, and motor behavior test (BBB locomotor rating scale, Grid walk test) was examined at 3, 7, 14, and 21 days. For the observation of damage change and size of the organized surface in spinal cord, histopathological studies were performed at 21 days by H & E, and BDNF(brain-derived neutrophic factor) & Trk-b immunohistochemistry studies were performed at 1, 3, 7, 14, 21 days. According to the results, treadmill exercise can play a role in facilitating recovery of locomotion following spinal cord injury. Specially, moderate-intensity treadmill exercise after SCI induction was most improvement in functional recovery and histological change.

방사선 생물학적 효과(Radio biological effectiveness, RBE)를 선량에 대부분 의존하는 X선과 달리 탄소빔 의 경우 LET의 변화량은 반드시 고려되어야할 사항이다. 이는 X선 과는 극히 대조적인 선량 분포도를 갖 고 있기 때문이며 LET의 변화량이 중요한 이유가 된다. 따라서 기존의 LQ 모델이나 회복생존모델의 경우 이러한 점이 감안되지 않아 탄소빔의 분할 조사 시 문제점을 보이며 오류를 보이고 있다. 본 연구에서는 약 75keV/μm의 고LET 탄소빔 분할 조사 시 Potentially Lethal Damage Repair (PLDR)의 발생양을 확인하고 약 13keV/μm 저LET 조사와 비교하여 현저히 감소하였음을 확인하였다. PLDR의 감소에 따라 생존율 또한 감소하였다. 따라서 탄소빔의 생물리학적 모델 개발에 LET의 변화량은 반드시 고려되어져야 할 것으로 보 인다.

이 연구는 수중 운동, 균형 훈련과 복합 운동이 파킨슨 유발 흰쥐 모델에 미치는 영향을 관찰하기 위해 수산화도파민(6-hydroxydopamine)을 흰쥐의 좌측 내측전뇌다발에 주사하여 파킨슨 모델을 제작하였다. 실험동물은 수중 운동을 적용한 실험군 I, 균형 훈련을 적용한 실험군 II, 복합 운동(수중 운동+균형 훈련)을 적용한 실험군 III, 수술 후 표준사육장에서 운동을 적용하지 않은 대조군으로 배치하였다. 수술 후 7일, 14일, 21일에 실험동