Recently,mushrooms have received attention because they are material of nutritious food health-stimulating properties and medicinal effects. For the purpose of application the antihypertensive Pholiota adiposa and S. cerevisiae into development of new functional traditional rice wine, optimal fermentation condition and sensory evaluation of functional traditional rice wines were investigated and further its angiotensin-I converting enzyme(ACE) inhibitory activities were determined. Addition of antihypertensive Pholiota adiposa ASI 24012 into the mash was unaffected to ethanol production. The best acceptability showed in the PS-1 traditional rice wines which was brewed byaddition of 0.1% Pholiota adiposa ASI 24012 fruiting body into mash containing antihypertensive S. cerevisiae and cooked and also showed high ACE inhibitory activity of 78.3%.

Lactic acid bacteria (LAB) are industrially important microorganisms for probiotics. The recent widespread application of LAB for preparation of functional food is attributable to the accumulating scientific evidence showing their beneficial effects on human health. In this study, we isolated and characterized plant-derived LAB that show angiotensin-converting enzyme (ACE) inhibitory and antioxidant activities. The selected strain K2 was isolated from Kimchi, and identified as Lactobacillus plantarum by 16S rRNA gene analysis. The strain grew under static and shaking culture systems. They were also able to grow in different culture conditions like 25℃∼37℃ temperature, 4∼10 pH range and ∼6% NaCl concentration. L. plantarum K2 was highly resistant to acid stress; survival rate of the strain at pH 2.5 and 3 were 80% and 91.6%, respectively. The strain K2 also showed high bile resistance to 0.3% bile bovine and 0.3% bile extract with more than 74% of survival rate. The cell grown on MRS agar plate containing bile extract formed opaque precipitate zones around the colonies, indicating they have bile salt hydrolase activity. The strain showed an inhibitory activity against pathogenic bacteria such as Escherichia coli, Staphylococcus aureus and Listeria monocytogenes; antibacterial activity was probably due to the lactic acid. The K2 strain showed relatively higher autoaggregation values, antihypertensive and antioxidant activities. These results suggest that L. plantarum K2 could be not only applied as a pharmabiotic for human health but also is also starter culture applicable to fermentative products.

The underground parts of foso rugoso(Rosaceae) , which have been used as an antidiabetic in the folk medicines of Korea, lowered the blood pressure inthe normal rat . And from the chloroform soluble fraction, euscaphic acid wasisolated with β -sitosterol and campesterol .