Potentillae Chinensis Herba 추출물의 항산화 효능 평가를 위해 DPPH 자유라디칼 소거 활성 과 ABTS 양이온 라디칼 활성 평가를 시행하였다. 세포 실험에서 항염증 평가를 위해 호흡기 점막 상피세 포 NCI,H292와 RAW264.7 세포 대상으로 항염증 효능을 평가하였다. 그 결과, DPPH 자유라디칼 소거 활성과 ABTS 양이온 라디칼 활성 모두 농도 의존적으로 항산화 활성이 증가하는 것으로 나타났다. 세포 MTT 분석 결과, 각 농도 100 μg/ml로 처리한 경우 NCI-H292 세포의 생존율이 70% 미만으로 감소하 였고, 이후 실험은 50 μg/ml로 진행하였다. 항염증 효능 평가에서는 NO생성, TNF-α, IL-1β, PGE2가 감소하였고, COX-2도 50 μg/ml에서 유의하게 감소하였다. Potentillae Chinensis Herba 추출물과 생물 전환 추출물의 뮤신 단백질 발현은 MUC5AC 발현이 유의하게 감소하는 것으로 관찰되었다. 이상의 결과 는 Potentillae Chinensis Herba의 호흡기 점액 단백질 발현을 도와 염증을 억제하는 기능성 소재로 활용하 는데 가치가 있음을 알 수 있다.

The aging society are causing complicated problems from chronic diseases such as diabetes, heart disease in aged patients. Recently Covid pandemic swept across global aging societies and put aged people with chronic disease more vulnerable to mobidity. Therefore, from view of preventive and precision medicine, remote monitoring an aged people with chronic disease is an important issue than ever. Smart health care systems as remote monitoring is so called telemetry system which enable doctors or health care providers to manage remotely to consult, diagnose and treat patients with chronic disease and infectious disease as well. The goal of telemetry system is to meet timely medical need in aged patients in distant place through communication technologies. Through technological breakthrough, particularly in real-time health care industry, Telemetry system with realtime mornitoring of heart rhythm and blood glucose level can play an important role in managing healthcare services in aged patients. This report introduces a comprehensive and inclusive review on the usefulness of realtime patiens monitoring with wearable sensors in telemedicine applications. The findings of this report are as follows: (1) The advantage of real-time monitoring and blood glucose level and biofeedback based on visual data (2) The advantage of realtime-monitoring heart rhythm coupled with blood glucose level. (3) There is an additional need to produce a digital imaging from protable diagnostic divices such as X-ray and ultrasound.

The purpose of this study was to compare the validity of obesity indices among the body mass index (BMI), waist circumference (WC), and body fat percentage (BF%), and to determine which is the most useful index to predict the risk of chronic diseases of elderly people. This study was conducted as a cross-sectional study at welfare centers in Seoul. The total number of subjects was 261 (68 men and 193 women) with age ≥60 years. The distribution of obesity using 3 obesity indices in the subjects with hypertension, diabetes, or arthritis was BF%>WC>BMI in elderly men and WC>BF%>BMI in elderly women. In elderly women, odds ratios (ORs) for hypertension in BMI and WC quartiles were significantly increased in quartile 2 and 3 (p<0.05). The ORs for hypertension, hyperlipidemia, and arthritis in BF% quartiles were significantly increased in quartile 3 and 4 (p<0.05). The BF% was sensitive obesity index for predicting the occurrence of chronic disease in men, and the WC was sensitive index in women. Our results suggested maintaining BMI less than 23.5 kg/m2, WC less than 82 cm, and BF less than 35% in order to prevent chronic diseases in elderly women.

목적 : 도시와 농촌 간 만성질환이 있는 65세 이상의 노인을 대상으로 일반적 특성에 따른 신체활동 실천율과 신체활동에 따른 삶의 질 차이를 알아보고자 한다. 연구방법 : 만성질환을 갖고 있는 65세 이상 노인 1,039명을 연구 대상으로 하였다. 신체활동으로는 걷기, 유연성 운동,근력 운동을 조사하였고, 삶의 질은 EQ-5D (Euroqol-5 dimension)를 사용하여 삶의 질에 대한 자료를 수집하여 분석하였다. 결과 : 신체활동 실천율은 도시의 경우 연령, 성별, 배우자, 주택유형, 소득수준, 교육수준에 따라 유의한 차이를 보였고, 농촌의 경우 주택유형과 교육수준에 따라 유의한 차이를 보였다. 삶의 질에서, 도시의 경우는 걷기, 유연성 운동, 근력 운동을 실천 한 군의 운동능력, 자기관리, 일상생활활동, 통증/불편 영역에서 유의한 차이를 보였고, 농촌의 경우는 걷기를 실천 한 군의 운동능력에서 유의한 차이를 보였다. 결론 : 도시와 농촌 모두 만성질환 노인의 신체활동 실천율은 낮은 편이었고, 특히 도시보다 농촌에 거주하는 만성질환 노인의 신체활동 실천율이 더욱 낮게 나타났다. 만성질환노인의 신체적 기능을 높이고, 삶의 질에 긍정적인 영향을 미칠 수 있는 신체활동의 중요성에 대한 인식이 필요하다.

This study examined the effects of the fragrance of lemons on increasing concentration and decreasing stress in the in the elderly with geriatric disease in a nursing home. This study was conducted 24times from Jan15. 2004 to July22. 2004 The program was distinguished between the group of control and lemon treatment. The group of control was conducted just horticultural therapy. The group of lemon treatment was run parallel horticultural therapy with the treatment of fragrance of lemons. Blood pressure was measured to distinguish between hypertension and hypotension. The result of hypertension people in the group of control was that systolic blood pressure was 134.3 as average before horticultural therapy and 134 after horticultural therapy. The pressure after horticultural therapy was more -0.3 different than the before. Diastolic blood pressure was 74.3 before and 72.7 after. The pressure after horticultural therapy was more -1.6 different than the before. The result of hypertension people in the group of lemon treatment was that Diastolic blood pressure was 134 as average before lemon treatment and horticultural therapy and 131.3 after lemon treatment and horticultural therapy. The pressure after horticultural therapy was more -2.7 different than before. Minimum blood pressure was 72 before and 72.3 after . The pressure after horticultural therapy was more +0.3 different pressure than the before. The result of hypotension people in the group of control was that systolic blood pressure was 111.3 as average after horticultural therapy. It was not so different between before and after. Diastolic blood pressure was 64.3 after therapy. The pressure was more +1.6 different pressure than the before. In case of pulse rate, the group of control was 79 as average before horticultural therapy and 78.7 after. The pressure was more -0.3 different average than the before. In contrast, the group of lemon treatment was 73.8 before the therapy and treatment of fragrance of lemons and 77.3 after. The pressure was more +3.5 different average than the before. most patients were improved their characters after this program (except C and E) as the result of character test. Therefore, following or this result of study, horticultural program with citrus fragrance of lemons that is helpful to concentration and anti-stress is effective for geriatric diseases especially stability of emotion.