This study was conducted to investigate the effectiveness of a nutrition and exercise education program on weight control and nutrition knowledge. The nutrition-exercise educational period was 12 weeks. The subjects were 160 adult women with an average age of 48.1 years. We investigated general characteristics, diet history, eating habits, and intake frequencies of six food groups by survey. A total of 94 women among the subjects participated in the pre and post nutrition knowledge evaluations and anthropometric data assessment. After the program, body weight, body mass index (BMI), and waist circumference significantly decreased. Further, % of body fat decreased, but not significantly. BMI significantly decreased (p<0.001) from 25.14 to 24.80 kg/m2, and waist circumference significantly decreased (p<0.001) from 79.72 to 77.63 cm. The nutrition knowledge scores of subjects significantly increased (p<0.001) from 8.01 to 9.03. However, there was little change in employment. These results suggest that the nutrition-exercise education program may improve obesity index and nutrition knowledge. However, it is necessary to develop a specialized weight control program for workers.