본고(本考)는, 명리학(命理學) 관점에서 음양오행(陰陽五行)의 생극제화(生剋 制化)로 인한 부조화(不調和)로부터 인체에 질병이 발현(發現)한다는 점에 주목 하였다. 병인(病因)은 간지(干支)의 오행이 편왕(偏旺)이나 편쇠(偏衰)의 시점에 평형(平衡)이 실조(失調)됨으로써 발현한다. 그렇다면 과연 수많은 질병의 발현 시점을 어떻게 정확하게 인지할 것인가? 또 여기서 강조하는 ‘화해(和解)’라는 방법이나 방안은 그 병리적(病理的) 근거를 담보(擔保)할 수 있는가? 본고는 이 두 가지에 대한 문제의식에서 출발하였다. 여기서 강조하는 화해방안은, 모두 건강한 일상을 추구하려는 인간의 욕구를 위한 방안이라고 할 수 있다. 본고에서는, 음양오행의 생극제화로 인한 부조화로부터 발현한 질병을 치 유하기 위한 방법 즉 화해방안을 다음과 같이 다섯 가지로 제시하였다. 첫째, 어느 한 오행의 편쇠(偏衰)로 인한 질병의 경우에는, 편쇠한 오행을 동류(同流) 또는 이류(異類)가 부조(扶助)하거나, 또는 편쇠한 오행을 생하는 방안이다. 둘째, 어느 한 오행의 편왕(偏旺)으로 인한 질병의 경우에는, 편왕한 오행의 생을 받는 오행을 통해 누설(漏洩)시키거나, 또는 편왕한 오행을 극하는 오행으로 설기(洩氣)하는 방안이다. 셋째, 환경적 요소를 변화시키는 방안으로서 시⋅공 간적 개념을 활용하거나 변용하는 것이다. 넷째, 오미(五味)를 중심으로 음식 섭취를 조절하는 방안으로서 이른바 보완과 조화를 위한 균형적인 식단을 꾸 미는 것이다. 다섯째, 운기(運氣)의 변화를 모색하기 위해서 성명(姓名)을 개명 (改名)하는 화해의 방안이다. 우리는 이러한 방법을 통하여 운기(運氣)의 변화 와 심리적 안녕(安寧)을 구축할 수 있는 것이다. 본고에서 제시한 이러한 화해방안을 일상생활에 적용한다면, 약리적(藥理 的) 효과와는 또 다른 측면에서 심리적(心理的) 안녕(安寧)을 확보하거나 유지 하는 효과가 분명히 나타날 것으로 기대한다.

This study aimed to identify prognostic factors and describe the treatment outcomes of multidrug therapy in dogs with meningoencephalomyelitis of unknown etiology (MUE). A total of 23 dogs diagnosed with MUE were treated with prednisolone in combination with cyclosporine, cytosine arabinoside (CA), leflunomide, and mycophenolate mofetil. Based on the survival time, these dogs were divided into two groups: group A (n = 10), surviving for < 100 days, and group B (n = 13), surviving for > 100 days. Signalment, seizure activity, cerebrospinal fluid (CSF) analysis results, and magnetic resonance (MR) imaging findings were reviewed. Survival studies were conducted to investigate the association of each prognostic factor and treatment with the clinical outcome. There were no significant differences in age, sex, body weight, occurrence of seizures, cell number and protein concentration in the CSF, or location of lesions between groups A and B. Abnormal MR features were more frequently observed in group A than in group B. It was identified that the longest median survival time was administration of multi-drug therapy including CA. In conclusion, abnormal MR features were associated with poor prognosis in dogs with MUE and CA-based multi-drug therapy could be considered the most effective treatment of MUE.

A 4-year-old, female, Maltese dog with bilateral hind limb ataxia was brought to Gyeongsang National University Animal Medical Center (GAMC). Based on the previous medical and imaging records, the patient was presumptively diagnosed with a primary brain tumor of the right temporo-occipital lobe on magnetic resonance imaging (MRI) in a local animal hospital. Hydroxyurea and prednisolone therapy was initiated, and the neurological signs transiently improved. Approximately 5 months after the treatment, ataxia recurred and the patient was referred to GAMC. Upon admission, MRI at the same anatomic level as in the previous MRI was performed. Results showed inflammatory brain lesions, not brain neoplastic changes. Considering this finding, the dog was tentatively diagnosed with meningoencephalitis of unknown etiology (MUE). We added oral imatinib mesylate (10 mg/kg every 24 h), and the dosage of prednisolone was increased to 1 mg/kg twice daily. Hydroxyurea was discontinued. A rapid improvement in neurological signs was observed after the initiation of imatinib mesylate treatment. Approximately 2 months after the treatment, the size of the inflammatory lesion remarkably decreased on repeat MRI. The patient had been doing well, and there were no overt neurological signs 259 days after the initiation of imatinib mesylate therapy. We describe a case of MUE in a dog that was successfully managed with imatinib mesylate.

The need for skin health care is newly recognized in accordance with the importance and needs of skin care due to harmonious interpersonal relation. In this study, collected 202 questionnaire sheets in Seoul were analyzed by SPSS 18.0 program through data coding and data cleaning, and frequency analysis for general characteristics was done. Heredity, environmental factors and management condition of acne, and the differences according to general characteristics were analyzed by Crosstabs. Mainly, women used skin care shop and their age groups were varied from twenties to fifties. Recognition of skin trouble were compound(42.1%), and significant statistical difference(p<.05), while oily or compound to man and compound or acne skin to woman were observed. First occurrence of acne was generally middle school(33.7%). Facial acne progress areas was cheek(36.1%), forehead(30.7%), chin(28.2%) and neck(5.0%) in descending order, and present state of acne was in progress(60.9%). Etiologic factors were stress(39.1%), pre and post-menstruation(22.8%), environment(20.8%), heredity(17.3%). There was significant statistical difference between gender(p<.01). Treatment places were at dermatologist(45.0%) and special skin care shop(27.2%). The most reliable place for treatment was special skin care shop(44.6%) and dermatologist(42.6%). It suggested that in acne of skin trouble, age groups of customers could be varied among male and female and in order to meet such requirements of customers, high quality service ought to be provided so that acne care could satisfy customers with the differentiated and careful service.

만성 췌장염은 외분비 및 내분비기능의 저하를 유발하는 진행성의 염증 그리고 섬유화로 특징지어지는 췌장의 비가역 적인 염증질환이다. 만성 췌장염은 크게 석회화, 폐쇄성 그리고 스테로이드 반응 형태로 분류되나, 일반적으로 특별한 언급 없이 만성 췌장염이라고 하면 췌장실질 석회화 형태의 만성 췌장염을 일컫는다. 만성 췌장염의 원인으로는 다양한 변이, 여러 유전자 사이의 상호 연관성 그리고 환경의 영향 등이 복합적으로 작용한다고 여겨진다. 진단은 주로 전산화단층촬 영술이나 자기공명담췌관조영술과 같은 영상 검사가 주로 이용되었으나 최근에는 초음파내시경이 많이 이용되고 있다.

The purpose of this study is evaluating about the survival rate and causes of failed implants. In this study, the 371 implants was evaluated for the survival rate and failing factors of implant. The survival rate was 96.5%. The failure rate was 3.5%. The average life time of implants was 50 months. The average age of patients treated was 49 years old. In total 371 cases, 13 cases failed implants were removed. The causes of failing implants were poor oral hygiene, excessive occlusal loading, smoking, and etc. The leading causes of failed implants were improper oral hygiene and excessive occlusal loading. In conclusion, I suggest that the periodic plaque control and occlusal force management can improve the survival rate of implants.

Stroke is a serious disease despite recent improvement in medical and surgical treatment. Hence, identification of modifiable risk factors for stroke is important. This case-control study was done to demonstrate that relationship between smoking, alcohol consumption, obesity, perception of saltness and the incidence of stroke and to identify that smoking, alcohol consumption, obesity and perception of saltness, after adjusting for age, hypertension. A structured interview was carried out from April 15, 1996 to May 3, 1996 in Yonsei Medical Center. The study group consisted of 59 neurologically confirmed stroke patients as the study group and 59 non-stroke patients as controls. Analysis of the data was done by means of -test and logistic regression analysis. The results were as follows. In the study group: 1) Hypertension in males had a 10.2 odds ratio (p<0.05), cardiovascular disease in females had a 11.3 odds ratio (p<0.05) and a farnily history of stroke in males had a 3.1 odds ratio (p<0.05). 2) Females smoking one or more cigarettes had a 8.3 odds ratio (p<0.1), but males had no direct relationship with odds ratio of 1.5 (non-significant). 3) Alcohol consumption in males had a 0.4 odds ratio, and in females had a 0.8 odds ratio. The odds ratio was decreased in alcohol consumption group (non-significant). 4) Males with more than 20 cigarettes pack-years history had a 2.5 odds ratio (p<0.05), more than 25 Body Mass Index had a 3.1 odds ratio (p<0.05) and more than 220 ml ethanol weekly consumption had a 1.5 odds ratio (non-significant). 5) Female smokers had a 8.3 odds ratio (p<0.1), drinkers a 0.8 odds ratio and more than 25 Body Mass Iidex, a 43.1 odds ratio (p<0.05). 6) Females without saltness perception from a 0.5% salt solution had a 6.8 odds ratio (non-significant). 7) By logistic regression analysis independent risk factors for stroke in males were found to be hypertention, age, and obesity. The study was limited because number of subjects was too small for practical implications. However, like as other results, this study suggest that people should be advised to control hypertension, and obesity since these carry a risk of stroke.

참깨줄기의 반쪽부분(部分)만이 특징적으로 변색(變色)되며 결국은 식물체전체(植物體全體)가 고사(枯死)되는 병미(病微)이 장려품종(奬勵品種)인 광산(廣産)깨와 풍년(豊年)깨가 심겨진 포장(圃場)에서 관찰(觀察)되었다. 병미(病微)은 처음에 줄기의 한쪽 부분(部分)만이 수침상(水浸狀)의 줄무늬(條斑)형태(形態)로 변색(變色)되며, 병징후기(病徵後期)에는 변색부위상(變色部位上)에 황백색(黃白色)선홍색(鮮紅色)의 Fusarium 포자퇴(胞子堆)들이 많이 형성(形成)된다. Fusarium oxysporum에 감염(感染)된 참깨 유묘(幼苗)에서는 주로 시들음 증상(症狀)이 나타나지만, 성묘(成苗)에서는 토양접종(土壞接種)이나 상처접종(傷處接種)에 의해 줄기반쪽썩음증상(症狀)을 재현(再現)시킬 수 있었다. 본(本) 병해(病害)는 주로 생육후기(生育後期)인 7월하순(月下旬) 경에 많이 발생(發生)된다. 참깨줄기반쪽썩음증상(症狀)에서 분리(分離)한 Fusarium oxysporum의 균학적(菌學的) 특성(特性)을 이미 참께시들음병(病)에서 보고(報告)되어 있는 Fusarium 균(菌)들과 비교(比較)한 결과(結果) 본(本) 균(菌)은 F. oxysporum f. sp. sesame로 생각된다.

This study aimed to identify the respiratory viral etiology and clinical features in febrile neonates and young infants younger than 3 months of age. From June 2015 to March 2016, 126 patients who admitted to the pediatrics department of Kwangju Christian Hospital due to febrile illness (body temperature ≥ 38.0℃) without definite focus of fever. We tested nasopharyngeal aspiration specimens with real time reverse transcriptase polymerase chain reaction. Respiratory viruses identified in 66 patients, and not identified in 60 patients. Among identified viruses, the most common pathogen was rhinovirus. Respiratory virus identified patients showed significantly higher presence of sibling (p=0.015), sibling who attending day care center (p=0.022), respiratory symptoms of family members (p=0.022), concomitant respiratory symptoms of the patient (p=0.001).

자간전증은 임신중 흔히 발생하는 고혈압성 질환으로 임산부와 태아에 많은 의학적 문제를 유발하지만 발병 원인은 아직 규명되지 않고 있다. 원인 규명을 위한 최근의 연구는 태반 미토콘드리아 돌연변이가 그 원인일 가능성이 높아져 가고 있다. 본 고찰은 현재까지 진행되고 있는 자간전증의 원인으로 태반 미토콘드리아 돌연변이 가설을 뒷받침하는 여러 연구 결과를 살펴보고, 만일 그 가설이 타당하다면 향후 자간전증의 예방, 진단, 치료의 전략을 임상적으로 어떻게 응용