Abstract Purpose : This study analyzed physical properties using 1,6-Hexanediol diacrylate (HDDA) as an additive to improve functionality of hydrogel lens such as durability. It was checked whether HDDA can be applied as a crosslinking agent in place of ethylene glycol dimethacrylate (EGDMA). Methods : Polymerization used thermal polymerization and photopolymerization methods, and HDDA was added to each polymerization method at a ratio of 1∼20%. Optical and physical characteristics of the manufactured lens were evaluated by measuring spectral transmittance, refractive index, water content, tensile strength, contact angle, and AFM. Results : Regardless of the polymerization method, the tensile strength ranged from 0.232~0.408 kgf/mm2 in thermal polymerization and from 0.146~0.429 kgf/mm2 depending on the addition ratio of HDDA. In addition, as a result of using HDDA instead of EGDMA, it was confirmed that the physical characteristics of the lens were similar to that of EGDMA, and in the case of tensile strength, HDDA was much improved. Conclusion : HDDA has been shown to be effective in improving the functionality of hydrogel lens and to improve stability and durability. In addition, it is believed that it can be used in various ways as an ophthalmic material as well as a photopolymerization crosslinking agent. Key words : Crosslinking agent, Tensile strength, 1,6-Hexanediol diacrylate, Hydrogel lens

목적 : 최근 전자기기의 발달로 인해 근거리 작업이 증가하고 있으며, 이로 인해 안 건강에 대한 우려가 증가함 에 따라 청광 차단에 대한 관심이 증가하고 있다. 방법 : 유해 광선 차단이 가능한 기능성 콘택트렌즈 소재 개발을 위해 reactive yellow 86을 안료 중합체에, 그리고 propyl gallate를 실리콘 하이드로겔 소재에 첨가제로 각각 사용하여 안 의료용 소프트 콘택트렌즈 제조에 적용하였다. 결과 : propyl gallate의 첨가량에 따라 접촉각이 68.25~42.50˚로 측정되었으며, 습윤성이 향상되는 것으로 나타났다. 또한, 제조된 컬러 소프트 콘택트렌즈는 산소투과성 및 습윤성이 우수함과 동시에 자외선 및 청광 차단 효과를 나타내었다. 결론 : reactive yellow 86 및 propyl gallate가 적용된 컬러 콘택트렌즈의 재료의 경우, 기본적인 안 의료용 하이드로젤 렌즈의 물성을 만족시킴과 동시에 우수한 자외선 및 청광차단 효과를 가지는 것으로 판단된다.

The physical and antibacterial properties of ophthalmic lenses fabricated by copolymerization with hydrogel monomers using two types of graphene were measured, and their usability as contact lens materials was analyzed. For polymerization, silicone monomers, including SID-OH, 3-(methacryloxy)propyl tris(trimethylsiloxy)silane, and decamethylcyclopentasiloxane, were used, and N,N-dimethylacetamide, ethylene glycol dimethacrylate as a crosslinking agent, and azobisisobutyronitrile as an initiator were added. Also, graphene oxide nanoparticle (GON) and graphene nanoplate (GNP) were used as an additive, and the physical properties of the lenses fabricated after copolymerization were evaluated. The fabricated lenses satisfied the basic physical properties of general hydrogel contact lenses and showed the characteristics of lenses with high water content, and the disadvantage of very weak durability, due to low tensile strength. However, it was confirmed that the tensile strength and antibacterial properties were greatly improved by adding GON and GNP. With GON, the oxygen permeability and refractive index of the fabricated lenses were slightly improved. Therefore, it was determined that the graphene materials used in this study can be used in various ways as a contact lens material.

목적: 본 연구는 trimethylsilyl methacrylate와 titanium silicon oxide 나노입자를 사용하여 친수성 하이드로젤 콘택트렌즈 재질을 중합하고 제조된 친수성 콘택트렌즈의 물리적, 광학적 특성을 분석하여 이들 물질들의 콘택트렌즈 재료로서의 활용도를 알아보았다. 방법: 고분자의 중합은 2-hydroxyethyl methacrylate, methyl methacrylate 및 n-vinyl pyrrolidone과 가교제인 ethylene glycol dimethacrylate를 기본 조합으로 하였으며, 개시제로는 AIBN을 사용하였다. 제조된 렌즈의 물성 변화를 알아보기 위해 trimethylsilyl methacrylate와 titanium silicon oxide를 첨가하여 중합하고 함수율, 굴절률, 산소투과도, 분광투과율을 측정하였다. 결과: 제조된 친수성 콘택트렌즈는 하이드로젤 콘택트렌즈의 기본물성을 만족하였으며, 첨가제인 trimethylsilyl methacrylate의 양이 증가함에 따라 산소투과도는 증가하는 것으로 나타났다. 또한 titanium silicon oxide 나노입자의 첨가는 친수성 렌즈 소재의 기본적인 물성을 변화시키지 않으면서 자외선을 차단하는 것으로 나타났다. 결론: 본 연구를 통해 trimethylsilyl methacrylate와 titanium silicon oxide는 콘택트렌즈의 기본적인 물성을 만족시키면서 고산소투과성 및 자외선 차단 콘택트렌즈 재료로 다양하게 활용될 수 있을 것으로 판단된다.