Prognosis of the patients with lung cancer with lung-to-lung metastasis are known to be poor and frequently old aged persons with multiple nodules on imaging study abandon more invasive procedure including bronchoscopy and VATS (Videoassisted thoracoscopic surgery) to get tissue confirmation. Sjogren’s syndrome (SS) associated lung lesion mimicking lung cancer has a chance to have more favorable diseases including lymphoma. A 78-year-old woman with SS was admitted due to slowly progressive exertional dyspnea and multiple nodules on imaging study. She and her family gave up invasive diagnostic procedures at first due to old age but short term rapid change of dyspnea and nodules on chest CT brought out invasive procedures and diffuse large B-cell lymphoma was diagnosed. Dyspnea and nodules on imaging were improved after R-CHOP chemotherapy.

Intramuscular lipoma is a rare benign tumor. It refers to infiltrating lipoma because it originates between skeletal muscle abundles and infiltrates into the intramuscular septa. Kransdorf reported that the majority of lipomas were located in the trunk, head/neck, and lower extremity. In addition, in research by Kindlom et al., on 43 cases of muscular infiltrative lipoma, there was no case involving the chest wall. We report on a case of intramuscular lipoma on the anterior chest wall. The lesion was removed completely and histopathological findings showed that mature adipocytes had infiltrated serratus anterior muscle in a diffuse manner. After treatment, the patient has shown no complication or evidence of recurrence.