Purpose: This study employed a non-equivalent controlled pre-post experimental design to create educational content on basic cardiopulmonary resuscitation(CPR) and defibrillators using augmented reality smart glasses and determine its impact on nursing students' clinical competence, self-efficacy, and satisfaction. Method: The participants were nursing students from “S” University. The experimental and control groups comprised 33 and 29 participants, respectively. The dependent variables are clinical competence, self-efficacy, and satisfaction. The experimental group utilized augmented reality smart glasses, while the control group watched videos on a tablet PC. The collected data were analyzed using t-tests, -tests, and ANCOVA through the SPSS 25 program. Results: Clinical competence was significantly higher in the experimental group (1.86±0.01) than in the control group (1.75±0.01; F=31.76, p<.001). Self-efficacy was significantly higher in the experimental group (9.00±0.11) than in the control group (7.94±0.12; F=39.04, p<.001). Similarly, satisfaction was significantly higher in the experimental group (4.95±0.09) than in the control group (4.69±0.30; t=4.494, p<001). Conclusion: Augmented reality-based CPR and defibrillation training is effective in Improving nursing students’ clinical competence, self-efficacy, and satisfaction.

CD63, a member of tetraspanin membrane protein family, plays pivotal role in cell growth, motility, signal transduction, host-pathogen interactions and cancer. In this work, the cDNA encoding CD63 homologue (TmCD63) was cloned from larvae of coleopteran beetle, Tenebrio molitor. The cDNA is comprised of an open reading frame of 705 bp, encoding putative protein of 235 amino acid residues. In silico analysis shows that the protein has four putative transmembrane domains and one large extracellular loop. The characteristic ‘Cys-Cys-Gly’ motif and ‘Cys188’ residues are highly conserved in the large extracellular loop. Phylogenetic analysis of TmCD63 revealed that they belong to the insect cluster with 50-56% identity. Analysis of spatial expression patterns demonstrated that TmCD63 mRNA is mainly expressed in gut and Malphigian tubules of larvae and the testis of the adult. Developmental expression patterns of CD63 mRNA showed that TmCD63 transcripts are detected in late larval, pupal and adult stages. Interestingly, TmCD63 transcript was upregulated the maximum 4.5 fold in response to DAP-type peptidoglycan during the first 6 h, although other immune elicitors also made significant increase in the transcript level at later time-points. These results suggest that CD63 might contribute to T. molitor immune response against various microbial pathogens.