The fall armyworm, Spodoptera frugiperda, has developed extremely high levels of resistance to chlorantraniliprole and other classes of insecticides in the field. As microRNAs (miRNAs) play important roles in various biological processes through gene regulation. we examined the miRNA profile of S. frugiperda in response to Chlorantraniliprole, Indoxacarb and Thiamethoxam. Transcriptome analysis showed significant changes in the abundance of some miRNAs after treatment of S. frugiperda larvae with LC20 concentrations of three insecticides. A total of 197 miRNAs were systematically identified from S. frugiperda, and 16, 9, 2 miRNAs were differentially expressed after treatments of three insecticides. Importantly, three miRNAs were significantly downregulated and three were upregulated by RT-qPCR after treatment the LC50 of three insecticides with S. frugiperda larvae. Microinjection of agomirs of these six miRNAs into S. frugiperda larvae resulted in significant changes in mortality rates when exposed to three insecticides. Additionally, we also screened potential target genes for some of differentially expressed miRNAs, which may play important roles in insecticide resistance development. These findings provide valuable insights into the molecular mechanisms of insecticide resistance and underscore the potential of miRNAs as targets for the development of novel pest control strategies in S. frugiperda.
한-아프리카 농식품 기술협력 협의체 (KAFACI)는 아프리카 농업 공통현안을 연구과제를 통하여 해결하고자 2010년에 출범하여 현재 한국 포함 20개국으로 구성되었다. 본 논문은 지난 10년간 회원국에서 수행한 결과를 바탕으로 KAFACI 회원 국과 비회원국 간의 양자 무역 흐름에 대한 국제 기술 협력의 영향을 분석하였다. 분석은 UN 상품 무역 통계 데이터베이스에서 2000년에서 2018년 동안 45 개 아프리카 국가 간의 양 자 무역 패널 데이터를 이용하였으며 국제 무역 중력 모델을 적용하였다. 또한, 내생성, 표본 선택 편의, 패널내의 상관관계 를 통제하는 표본 선택 기법을 적용한 핵크만 랜덤 효과 회귀 모형을 사용하였다. 분석결과 경험적 결과는 국제 기술 협력이 KAFACI 회원국과 비회원 국 간의 양자 무역 흐름에 긍정적인 영향을 미친다는 것을 보여준다. 이러한 연구 결과 이 외에도 KAFACI는 회원국과 아프리카 이외의 주요 무역 파트 너 간의 양자 무역 흐름을 크게 늘렸을 가능성이 있지만 여기서는 다루지 않았다. 또한 KAFACI 회원국의 기술 채택 수준과 비율은 무역을 잠금 해제하기 위해 경제의 공급 측면에 영향을 미치는데 중요하지만 여기에서는 다루지 않았다.
The present study aimed to investigate rapid weight loss (RWL) and consequent physical and psychological challenges among judo athletes at the national athlete training center in 2017. The following results were obtained. Judo athletes used weight loss methods such as “gradually reduce meal portion,” “skip meals,” “limit water intake,” “wear sweat suit for training,” and “use sauna,” and had physical and mental distress from such unhealthy weight management practices. Information about weight loss was obtained from “colleagues or senior athletes,” “Internet,” and “head coach or coach,” and not experts such as nutritionists or physicians. Thus, athletes are recommended to employ healthy weight control methods based on advice from experts, such as nutritionists and physicians
Augmented reality (AR) generates a enhanced and augmented reality by coupling virtual and real worlds. AR facilitates primary features: a permutation of real and virtual worlds, real-time interaction and an exact 3D process of virtual and real objects. AR offers a new level of interaction between their products and consumers by engaging them in a totally new environment. This study identifies the current state of AR marketing and future research directions. Concentrated on the marketing value of AR, the study enlightens the concept of AR marketing value, the role of value sharing, and opportunities and challenges creating customer value in the AR platforms.