Background: Sustaining regular exercise is a major public health challenge. Self-directed, goal-oriented exercise programs may enhance autonomy and adherence compared to traditional supervised approaches. Objects: This study evaluated the effects of an 8-week individualized, goal-oriented exercise program on physical fitness and body composition in college students and assessed the durability of these effects following an 8-week washout period. Methods: In a non-randomized, fixed-sequence design, 24 healthy young adults (19 males, 5 females) completed an 8-week self-directed exercise intervention, followed by an 8-week washout and an 8-week control period. Physical fitness (vertical jump, standing long jump, handgrip strength, one-leg stance) and body composition (body mass index, skeletal muscle mass, body fat percentage) were assessed. Data were analyzed using repeated-measures ANOVA and effect size estimates. Results: Significant improvements were observed in all fitness measures post-intervention (p < 0.01). Large effect sizes were found for vertical jump (Cohen’s dav = 0.87) and standing long jump (dav = 0.99), while handgrip strength and one-leg stance showed moderate effects (dav ≈ 0.65). However, no consistent changes were detected in body composition variables. Fitness gains declined rapidly during the washout period, indicating transient adaptation. Conclusion: An 8-week goal-oriented, self-directed exercise program effectively improved physical fitness but not body composition in young adults. These findings support the utility of autonomy-supportive models, though the rapid reversal of gains highlights the critical need for sustained engagement strategies.

Background: Somatic cell nuclear transfer (SCNT) is a prominent technology that can preserve superior genetic traits of animals and expand the population in a short time. Hematological characters and endocrine profiles are important elements that demonstrate the stability of the physiological state of cloned animals. To date, several studies regarding cloned camels with superior genes have been conducted. However, detailed hemato-physiological assessments to prove that cloned camels are physiologically normal are limited. In this study, We evaluated the hemato-physiological characteristics of cloned male and female dromedary camels (Camelus dromedaries). Methods: Therefore, we analyzed variations in hematological characteristics and endocrine profiles between cloned and non-cloned age-matched male and female dromedary camels (Camelus dromedaries ). Two groups each of male and female cloned and non-cloned camels were monitored to investigate the differences in hemato-physiological characteristics. Results: All the animals were evaluated by performing complete blood count (CBC), serum chemistry, and endocrinological tests. We found no significant difference between the cloned and non-cloned camels. Furthermore, the blood chemistry and endocrine profiles in male and female camels before maturity were similar. Conclusions: These results suggest that cloned and non-cloned camels have similar hematological characteristics and endocrine parameters.

Background: Canine induced pluripotent stem cells (iPSCs) are an attractive source for veterinary regenerative medicine, disease modeling, and drug development. Here we used vitamin C (Vc) to improve the reprogramming efficiency of canine iPSCs, and its functions in the reprogramming process were elucidated. Methods: Retroviral transduction of Oct4, Sox2, Klf4, c-Myc (OSKM), and GFP was employed to induce reprogramming in canine fetal fibroblasts. Following transduction, the culture medium was subsequently replaced with ESC medium containing Vc to determine the effect on reprogramming activity. Results: The number of AP-positive iPSC colonies dramatically increased in culture conditions supplemented with Vc. Vc enhanced the efficacy of retrovirus transduction, which appears to be correlated with enhanced cell proliferation capacity. To confirm the characteristics of the Vc-treated iPSCs, the cells were cultured to passage 5, and pluripotency markers including Oct4, Sox2, Nanog, and Tra-1-60 were observed by immunocytochemistry. The expression of endogenous pluripotent genes (Oct4, Nanog, Rex1, and telomerase) were also verified by PCR. The complete silencing of exogenously transduced human OSKM factors was observed exclusively in canine iPSCs treated with Vc. Canine iPSCs treated with Vc are capable of forming embryoid bodies in vitro and have spontaneously differentiated into three germ layers. Conclusions: Our findings emphasize a straightforward method for enhancing the efficiency of canine iPSC generation and provide insight into the Vc effect on the reprogramming process.

Efficiently detecting the nearest navigational dangers in Electronic Chart Display and Information Systems (ECDIS) remains pivotal for maritime safety. However, the software implementation of ADMAR(Automatic Distance measurement and Ranging) functionality faced challenges, necessitating extensive computations across ENC cells and impacting real-time performance. To address this, we present a novel method employing dynamic programming. Our proposed algorithm strategically organizes nodes into a tree structure, optimizing the search process towards nodes likely to contain navigational hazards. Implementation of this method resulted in a notable sevenfold reduction in computation time compared to the conventional Brute Force approach. Our study established a direct correlation between the ADMAR functionality and node count, achieving error margins deemed acceptable for practical navigation scenarios. Despite this theoretical progress, minor errors in results prompt further refinement. Consequently, future iterations will explore varying values for N, considering hierarchy and cell sizes to enhance algorithmic precision. This research signifies a potential advancement in optimizing navigational danger detection within ECDIS, offering a promising avenue for improved efficiency. By introducing a dynamic programming-based approach, we have streamlined the detection process while acknowledging the scope for algorithmic refinement in subsequent studies. Our findings underline the feasibility of employing dynamic programming to enhance navigational danger detection, emphasizing its potential in ensuring maritime safety. This work lays a foundation for future research endeavors, aiming to fine-tune algorithms and advance navigational safety measures in ECDIS.

This study analyzed the relationship between efficient pitchers and teams advancing to the postseason in Korean professional baseball through DEA. A total of 1,133 pitchers who threw more than one inning from the 2014 season to the 2018 season were selected for this study. For DEA analysis, input variables were selected as annual salary and inning output variables as Wins, Saves, and Holds and the number of efficient pitchers for each season was classified using the input-oriented BCC model. After that, it was divided into two groups based on joining the postseason or not, and the number of efficient pitchers was compared through a prop test. As a result of the analysis, the groups that advanced to the postseason in the rest of the season except for the 2014 and 2017 seasons had more efficient pitchers. Considering that the 2014 season recorded the highest WAR (Wins Above Replacement) at 183.56 compared to other seasons, most pitchers threw well, and in the 2017 season, they made more mistakes in pitching than in other seasons, but they performed well in batters. The results of this study have expanded the research field using efficiency analysis in professional baseball and can be used as useful data for practical research.

This study was conducted at the National Institute of Animal Science (NIAS) from 2010 to 2017 to develop a late-maturing variety with high productivity for cultivation in the southern region of South Korea. The new variety of Italian ryegrass, ‘IR901’, was a late-maturing variety, and its heading date was 22 May, 17 days later than that of the control variety ‘Kowinearly’. ‘IR901’ had a flag leaf width of 11.2 mm, flag leaf length of 31.8 cm, and plant length of 103 cm on its heading date. The combined average dry matter yield of ‘IR901’ in all three adaptability evaluation regions (Cheonan, Pyeongchang and Haenam) was 7,747 kg/ha, which was similar to that of the ‘Kowinearly’ variety (7,734 kg/ ha). However, the average dry matter yield over three years in Cheonan and Pyeongchang was 82% and 96%, respectively, compared to that of the control, which was most likely because of the poor cold tolerance of ‘IR901’. By contrast, in Haenam, in the southern region, the average dry matter yield of ‘IR901’ was 19% higher than that of the ‘Kowinearly’ variety. The proportions of crude protein (CP), total digestible nutrients (TDN), acid detergent fiber (ADF), and neutral detergent fiber (NDF) in ‘IR901’ were 8.6%, 59.7%, 36.9%, and 54.8%, respectively; the proportions were 0.2% lower, the same, the same, and 2.5% lower than those in the ‘Kowinearly’ variety. The determined in vitro dry matter digestibility (IVDMD) of ‘IR901’ was 72.2% higher than that of ‘Kowinearly’ (67.2). In general, of the two varieties, the forage quality of ‘IR901’ was marginally superior to that of ‘Kowinearly’.

This study conducted a survey and evaluation on ‘The 2021 Jeju World Natural Heritage Festival’ with a framework of various stakeholders related to festivals. While aiming for the essential context of the celebration, we tried to find suggestions to ensure the continuity of the celebration and the designation of the World Natural Heritage. As a methodology, surveys and interview surveys were conducted in parallel with the framework of multifaceted evaluation. To summarize the important contents presented as policy suggestions, first, it is necessary to expand the concept of ' encounter with hidden nature' from the positivity of the concept of 'encounter with hidden nature' to have fellowship with mankind about natural heritage. For reference to this, efforts should be made to secure the continuity of the designation of World Natural Heritage through a contextual approach using the frame of 'encounter'. Second, since the participation of experts can help in many ways, it is necessary to encourage many experts to participate as a staff or activist. Third, it is necessary to sublimate Jeju's natural heritage into a public celebration without damaging it. Finally, it should be a festival centered on local communities and local residents. It is necessary to actively seek a system in which the World Natural Heritage Village Preservation Association, which will be created (tentative name), will be centered and promoted by the villagers.