Scabies, caused by an infestation of the skin with the itch mite (Sarcoptes scabiei), is highly contagious and classified as a prevalent neglected tropical diseases. The current diagnostic approach relies solely on clinical judgment based on symptoms, history, and microscopic observation by an experienced dermatologist. To enhance sensitivity and specificity, we developed an alternative method based on mite-derived DNA. Our method involves a quick DNA release from skin scraping samples and Loop-Mediated Isothermal Amplification (LAMP) targeting the scabies mite-specific DNA sequences, enabling diagnosis within 30 minutes. Importantly, no cross-reactivity was observed when the sample was contaminated by two house dust mite species, and false positives were barely detected. Currently, we are in the process of developing a Point-of-Care Testing (POCT) kit for a scabies survey targeting school-age children in Timor-Leste as a global health project.

본 연구는 해수유동모델을 이용하여 하계 한국 남해안 양식장 부근에서 수온의 시·공간적인 분포를 파악하였다. 한국 남해 조류의 흐름은 창조시 서향, 낙조시 동향하며, 쓰시마 난류의 흐름은 50 m보다 깊어지는 외양에서 연안에 비해 강하게 동북향 하였다. 조류, 바람, 쓰시마 난류 및 실시간 수온을 고려한 해수유동에서 하계 수온의 분포는 반폐쇄성 해역에서 26~28℃로 높게 나타났으며, 외양으로 갈수록 낮아져 18~22℃로 나타났다. 반폐쇄성 내만의 형태를 가지는 해역의 해수교환량을 계산한 결과 광양만 10,331 m³/sec, 여수-가막만 16,935 m³/sec, 그리고 거제-한산만은 13,454 m³/sec로 나타났다. 해수교환량이 적은 해역일수록 수온이 비교적 높게 나타난다.

마산만에서 수치모델을 이용하여 해파리의 시·공간적 분포를 파악하였다. 먼저 3차원 해수유동모델(POM)을 이용하여 조석, 바람, 수온·염분의 효과를 고려한 잔차류를 계산하였다. 마산만의 마산항, 중공업단지, 가포신항에서 발생한 해파리의 거동을 파악하기 위하여 잔차류에 의한 입자추적자 모델을 이용하였다. 해파리의 분포는 마창대교 북쪽해역에서 최대인 2,533 개체수가 나타났다. 이와 같은 현상은 잔차류의 다방향으로 혼재하는 흐름과 지형적인 영향으로 판단된다. 해파리의 이동에 영향을 미치는 잔차류가 우세한 해역에서 외력조건에 따른 해파리의 집적도를 알아보기 위해서 조석잔차류, 취송류, 밀도류의 유형별 수치실험을 하였다. 특히 마산만의 마창대교와 마산만 입구인 모도해역에서는 취송류(바람에 의한 효과)가 해파리의 집적에 탁월한 것을 확인하였다.

Project management is a tool for smooth operation during a full cycle from the design to normal operation including the schedule, document, and budget management, and document management is an important work for big projects such as the JRTR (Jordan Research and Training Reactor). To manage the various large documents for a research reactor, a project management system was resolved, a project procedure manual was prepared, and a document control system was established. The ANSIM (Advanced Nuclear Safety Information Management) system consists of a document management folder, document container folder, project management folder, organization management folder, and EPC (Engineering, Procurement and Construction) document folder. First, the system composition is a computerized version of the Inter-office Correspondence (IOC), the Document Distribution for Agreement (DDA), Design Documents, and Project Manager Memorandum (PM Memo) works prepared for the research reactor design. Second, it reviews, distributes, and approves design documents in the system and approves those documents to register and supply them to the research reactor user. Third, it integrates the information of the document system-using organization and its members, as well as users’ rights regarding the ANSIM document system. Throughout these functions, the ANSIM system has been contributing to the vitalization of united research. Not only did the ANSIM system realize a design document input, data load, and search system and manage KAERI’s long-period experience and knowledge information properties using a management strategy, but in doing so, it also contributed to research activation and will actively help in the construction of other nuclear facilities and exports abroad.

Near-IR H2 emission features in the northern region of the Orion A giant molecular cloud were observed in the CO J = 1 → 0 line in search of CO outflows. Out of the 30 sources surveyed, CO line wings were detected toward 28 positions, suggesting a strong correlation between H2 jets and CO outflows. Blueshifted wings were detected toward 26 positions while redshifted wings were detected toward 15 positions, which suggests that there is a bias in the source selection. The bias is more severe in OMC 3 than in OMC 2. Since the protostars in OMC 3 are younger and more deeply embedded, the bias may be caused by the difference of extinction between blueshifted and redshifted outflows. Some physical parameters of the outflows were derived from the line profiles.

The purpose of this study is to measure the changes of regional cerebral blood flow (rCBF) and blood pressure (BP) of Cortex Acanthopanacis in rats, and to determine the effect of Cortex Acanthopanacis on phenylephrine (PE) induced contraction of isolated rat thoracic aorta. The measurement was continually monitored by laser-doppler flowmeter (Transonic Instrument, USA) and pressure transducer (Grass, USA) in anesthetized adult Sprague-Dawley rats through the data acquisition system composed of MacLab and Macintosh computer. Contractile force was measured with force displacement transducer under 1.5 g loading tension. The result of this experiment was as following; 1. Cortex Acanthopanacis did not effect the changes of rCBF and blood pressure significantly. 2. Contractions evoked by phenylephrine were decreased significantly by Cortex Acanthopanacis 3. L-NNA, ODQ, atropine and indomethacin significantly altered the relaxation of Cortex Acanthopanacis. 4. Propranolol did not change the relaxation of Cortex Acanthopanacis. These results indicate that Cortex Acanthopanacis did not change the rCBF and BP, but Cortex Acanthopanacis can relax PE induced contraction of isolated rat thoracic aorta and that this increasing contraction related to endothelium and various mechanism.