Gangliocytomas are non-metastasizing and slow-growing tumor. In the sellar region, the sympathetic nerve fibers normally do not exist. Therefore, isolated gangliocytomas had been rarely reported in the pituitary fossa. Herein, we present and review the gangliocytoma arising in sellar region associating with pituitary adenoma which is the most common tumor in pituitary gland.

Cellular angiofibroma is a benign mesenchymal tumor with uniform, bland, spindle cell differentiation accompanied by thick walled vessels. We report a 17-year-old male who was diagnosed cellular angiofibroma on his right spermatic cord. He had small (about 1cm sized), non-tender, painless, movable mass for 3 years but 1 year ago insidious size of mass increased. Histological finding showed features characteristic of cellular angiofibroma however that occurs almost exclusively in vulvar of middle aged women. In addition, benign mesenchymal neoplasms had similar histologic findings with angiofibroma, especially aggressive angiofibroblastoma, aggressive angiomyxoma and solitary fibrous tumor. Specific immunohistochemical stain profile of angiofibroma helpful of differential diagnosis. Local excision with clear resection margin and long-term follow up are the treatment of choice as local recurrence has been reported in a few case.

The purpose of this study is to evaluate which clinicopathologic factors are associated with central lymph node metastasis (CLNM) in papillary thyroid carcinoma (PTC). A total of 402 cases of PTC were divided into two groups: CNLM (+) and CLNM (-). In univariate analysis, CLNM showed correlation with sex, tumor size, multifocality, bilaterality, extrathyroid extension, and distance from the capsule. In multivariate analysis, male gender, >1 cm of tumor size, multifocallity and extrathyroid extension were significant risk factors for CLNM. Findings of this study suggest that clinicians should pay attention to the above mentioned significant risk factors when examining lymph node (LN) for deciding LN dissection.

Primary adenocarcinoma is a rare neoplasm of the urinary bladder, constituting approximately 2.5% of all primary bladder malignancies. Signet ring cell variant is even rarer, constituting approximately 0.5% to 2.0% of all primary carcinoma of the urinary bladder. However, glandular differentiation in the urinary bladder is relatively more common than primary adenocarcinoma of the urinary bladder. Therefore, diagnosis of primary adenocarcinoma of the urinary bladder can be very challenging, but of significant clinical importance. We report on a case of adenocarcinoma with mucinous and signet ring cell differentiation in the bladder dome in a 49-year-old female.

Malignant mixed tumor is an aggressive malignant neoplasm composed of heterologous malignant epithelial and stromal components. It is a rare neoplasm, accounting for 0.05 % of all salivary gland tumors and 0.16 % of all malignant salivary gland tumors. The tumor may occur in the background of a preexisting pleomorphic adenoma or may arise de novo. We report on an 84-year-old female who was diagnosed with carcinosarcoma on her left parotid gland. Microscopically, the tumor consisted of two components - mainly myxoid chondrosarcoma (75%), poorly differentiated carcinoma and a few remnants of benign pleomorphic adenoma in the periphery of the tumor.