As platforms become primary decision making tools, platforms for decision have been introduced to improve quality of decision results. Because, decision platforms applied augmented decision-making process which uses experiences and feedback of users. This process creates a variety of alternatives tailored for users’ abilities and characteristics. However, platform users choose alternatives before considering significant quality factors based on securing decision quality. In real world, platform managers use an algorithm that distorts appropriate alternatives for their commercial benefits. For improving quality of decision-making, preceding researches approach trying to increase rational decision -making ability based on experiences and feedback. In order to overcome bounded rationality, users interact with the machine to approach the optional situation. Differentiated from previous studies, our study focused more on characteristics of users while they use decision platforms. This study investigated the impact of quality factors on decision-making using platforms, the dimensions of systematic factors and user characteristics. Systematic factors such as platform reliability, data quality, and user characteristics such as user abilities and biases were selected, and measuring variables which trust, satisfaction, and loyalty of decision platforms were selected. Based on these quality factors, a structural equation research model was created. A survey was conducted with 391 participants using a 7-point Likert scale. The hypothesis that quality factors affect trust was proved to be valid through path analysis of the structural equation model. The key findings indicate that platform reliability, data quality, user abilities, and biases affect the trust, satisfaction and loyalty. Among the quality factors, group bias of users affects significantly trust of decision platforms. We suggest that quality factors of decision platform consist of experience-based and feedback-based decision-making with the platform's network effect. Through this study, the theories of decision-making are empirically tested and the academic scope of platform-based decision-making has been further developed.
This study was conducted to evaluate the effect of the exercise on elderly balance ability by using hippotherapy and therapeutic ball exercise. 10 patients were assigned to the hippotherapy group and they got with 30 minutes of hippotherapy. Another 10 elderly were assigned to the therapeutic ball group and they got with 30 minutes of therapeutic ball exercise. All procedures were repeated 5 times a week for the total of four weeks. To investigate the participants balancing abilities, the Time“ Up & Go”(TUG) and One Leg Stand Test(OLST) were evaluated. The results of study were significant differences between pre-test and post-test of TUG and OLST(p<.05), and there were no significant differences between hippotherapy and therapeutic ball exercise(p>.05). The conclusion showed that both the hippotherapy and the therapeutic ball exercises were effective on elderly balancing ability. Consequently, it would be better to practice therapeutic ball than hippotherapy for elderly exercise because the more economical and there is less restriction of space than the hippotherapy.
Transforming growth factor (TGF) family is well known to induce the chondrogenic differentiation of mesenchymal stem cells (MSC). However, the precise signal transduction pathways and underlying factors are not well known. Thus the present study aims to evaluate the possible role of C2 domain in the chondrogenic differentiation of human mesenchymal stem cells. To this end, 145 C2 domains in the adenovirus were individually transfected to hMSC, and morphological changes were examined. Among 145 C2 domains, C2 domain of protein kinase C eta (PKCη) was selected as a possible chondrogenic differentiation factor for hMSC. To confirm this possibility, we treated TGFβ3, a well known chondrogenic differentiation factor of hMSC, and examined the increased-expression of glycosaminoglycan (GAG), collagen type II (COL II) as well as PKCη using PT-PCR, immunocytochemistry and Western blot analysis. To further evaluation of C2 domain of PKCη, we examined morphological changes, expressions of GAG and COL II after transfection of PKCη -C2 domain in hMSC. Overexpression of PKCη-C2 domain induced morphological change and increased GAG and COL II expressions. The present results demonstrate that PKCη involves in the TGF-β3-induced chondrogenic differentiation of hMSC, and C2 domain of PKCη has important role in this process.