The manufacturing companies under Make-To-Order (MTO) production environment face highly variable requirements of the customers. It makes them difficult to establish preemptive production strategy through inventory management and demand forecasting. Therefore, the ability to establish an optimal production schedule that incorporates the various requirements of the customers is emphasized as the key success factor.
In this study, we suggest a process of designing the simulation model for establishing production schedule and apply this model to the case of a flat glass processing company. The flat glass manufacturing industry is under MTO production environment. Academic research of flat glass industry is focused on minimizing the waste in the cutting process. In addition, in the practical view, the flat glass manufacturing companies tend to establish the production schedule based on the intuition of production manager and it results in failure of meeting the due date. Based on these findings, the case study aims to present the process of drawing up a production schedule through simulation modeling. The actual data of Korean flat glass processing company were used to make a monthly production schedule. To do this, five scenarios based on dispatching rules are considered and each scenario is evaluated by three key performance indicators for delivery compliance. We used B2MML (Business To Manufacturing Markup Language) schema for integrating manufacturing systems and simulations are carried out by using SIMIO simulation software. The results provide the basis for determining a suitable production schedule from the production manager's perspective.
Catalpol, an iridoid glucoside, isolated from the root of Rehmannia glutinosa Libosch. It possesses a broad range of biological and pharmacological activity including anti-tumor, anti-inflammation and anti-oxidant by acting as a free radical scavenger. Therefore, in this study, the effects of catalpol on blastocyst development, expression levels of reactive oxygen species (ROS) and apoptotic index were investigated in porcine embryos. After in vitro maturation and fertilization, porcine embryos were cultured for 6 days in porcine zygote medium 3 (PZM-3) supplemented with catalpol (0, 100, 200 and 400 μM, respectively). Blastocyst development not significantly improved in the catalpol treated group when compared with control group. Otherwise, the intracelluar levels of ROS were decreased and the numbers of apoptotic nuclei were reduced in the catalpol (100 μM) treated porcine blastocysts (P<0.05). On the other hand, blastocyst development was significantly improved in the catalpol (100 μM) treated group when compared with the untreated catalpol group under H2O2 (200 μM) induced oxidative stress (P<0.05). Otherwise, the intracellular levels of ROS in catalpol (100 μM) treated group were significantly decreased in the untreated catalpol group under H2O2 (200 μM) induced oxidative stress (P<0.05). Furthermore, the total cell numbers of blastocysts were significantly increased (P<0.05) in the catalpol (100 μM) treated group under H2O2 (200 μM) induced oxidative stress, whereas numbers of apoptoic nuclei were significantly reduced (P<0.05). In conclusion, our results indicate that treatment of catalpol may have important implications for improving developmental competence and preimplantation quality of porcine embryos through its anti-oxidant and anti-apoptotic effect
The tropopause fold event that took place on January 1, 1997 over mid-region on the Korean Peninsula is examined by means of a numerical simulation based on a Mesoscale Model (MM5). The purpose of this paper is to investigate the effects of moisture in reinforcing a tropopause fold linked to an explosive cyclone. Two types of simulations were carried out; 1) simulations for moist conditions in which full physical and dynamic processes are considered and 2) simulations for dry conditions in which cumulus parameterization and cloud microphysics process are excluded. The results of the moist condition simulations demonstrate that the intensity of the central pressure of the cyclone was overestimated compared with the observed values and that the location of the center and the pressure deepening rates (-17 hPa/12 hr) complied with the observed values. The potential vorticity (PV) anomaly on the isentropic surface at 305 K continued to move in a southeast direction on January 1, 1997 and thus created a single tube of tropopause fold covering the northern and the middle area of the Korean Peninsula and reaching the ground surface at 0300 UTC and 0600 UTC. The results of the dry condition simulations show that the tropopause descended to 500 and 670 hPa in 0300 and 0600 UTC, respectively at the same location for the moist condition simulation; however, there was no deep tropopause fold observed. A comparison of the simulated data between the moist and the dry conditions suggests that a deep tropopause fold should happen when there is sufficient moist in the atmosphere and significantly large PV in the lower atmosphere pulls down the upper atmosphere rather than when the tropopause descends itself due to dynamic causes. Thus, it is estimated that moisture in the atmosphere should have played a crucial role in a deep tropopause fold process.
Titanium carbides are widely used for cutting tools and grinding wheels, because of their superior physical properties such as high melting temperature, high hardness, high wear resistance, good thermal conductivity and excellent thermal shock resistance. The common synthesizing method for the titanium carbide powders is carbo-thermal reduction from the mixtures of titanium oxide() and carbon black. The purpose of the present research is to fabricate nano TiC powders using titanium salt and titanium hydride by the mechanochemical process(MCP). The initial elements used in this experiment are liquid (99.9%), (99.9%) and active carbon(<, 99.9%). Mg powders were added to the solution in order to induce the reaction with Cl-. The weight ratios of the carbon and Mg powders were theoretically calculated. The TiC and powders were milled in the planetary milling jar for 10 hours. The 40 nm TiC powders were fabricated by wet milling for 4 hours from the +C+Mg solution, and 300 nm TiC particles were obtained by using titanium hydride.
We derived initial mass functions (IMF) of massive stars in three different regions of spiral arms within 2.5kpc from the sun. The derived IMF slope β β of Local arm stars is found to be −2.09∼−2.06 −2.09∼−2.06 , very close to that of Bisiacchi et al. (1983). For Sagittarius-Carina arm stars β β ranges from -1.77 to - 1.72 which is close to that of overall stars given by Germany et al. (1982). Possible causes inducing the regional difference in IMFs are discussed.
Frequent occurrence of off-type plants in a given cultivar has been a serious problem in both breeder's and farmer's fields. An experiment was designed to examine the differences in rate of occurrence of off-type plants among Tongil-type cultivars (high yielding cultivars derived from indica/japonica hybridization) from which the possible cause of higher occurrence of off-type plant in a specific cultivar was deduced. Among five Tongil-type cultivars examined for morphological variant in the field, only one cultivar, Dasanbyeo, had off-type plants. When analyzed with SSR markers, off-type plants showed different band patterns from original cultivar, having several extra bands in addition to cultivar-specific band, suggesting that off-type plants were originated from Dasanbyeo, rather than originated from mixing or mishandling of seed materials with other cultivars. The possible cause of off-type occurrence seems to be natural pollination with other cuItivars adjacent to the original cultivar during seed multiplication. This was supported from the observation that self-crossed progeny of the off type plants showed a wide range of variation of agronomic traits which could not be observed when there was a smaller introduction of genes to the fixed germplasm as happened in the case of cultivar mutation. Another evidence supported this idea that Dasanbyeo showed much of difference in floral organ and behavior to other cultivar to be subjected to higher out-crossing than other cultivars examined.