Background: Emotional labor, the management of feelings to create organizationally desired emotional displays, has been consistently associated with adverse health outcomes in Western populations. However, cultural context may fundamentally alter these relationships in Asian service economies. Objectives: To examine temporal trends in emotional labor prevalence and investigate associations between emotional labor and health outcomes among Korean service workers over a 17-year period. Design: Repeated cross-sectional study. Methods: We analyzed data from seven waves of the Korean Working Conditions Survey (2006-2023), comprising 271,039 observations. Emotional labor was assessed using validated items measuring frequency of hiding feelings and managing customer emotions. Health outcomes included psychological symptoms (depression, anxiety, fatigue) and physical symptoms (musculoskeletal disorders, headaches, gastrointestinal problems). We employed multivariable logistic regression, fixed-effects models, and mediation analyses, adjusting for sociodemographic and occupational factors. Results: Emotional labor exposure remained stable at approximately 3.0 (5- point scale) from 2014-2023. Health problem prevalence was consistently around 60% across all survey years. Contrary to hypotheses, emotional labor showed no significant association with health problems (OR=0.999, 95% CI: 0.993-1.005, P=0.735). These null findings persisted in fixed-effects analyses (β=-0.0003, P=0.736), gender-stratified models, and interaction tests. The Cochran-Armitage trend test revealed no temporal trends (P=0.865). Mediation analysis found no indirect effects through psychological hazards. Notably, this finding represents a paradoxical discovery that challenges Western-centric assumptions about the universality of emotional labor's health effects. Conclusion: Despite high statistical power and comprehensive methodology, we found no evidence linking emotional labor to health problems in Korean workers. These unexpected findings challenge the assumed universality of emotional labor's health effects and suggest cultural factors may fundamentally modify occupational stress pathways. Western-derived theoretical models may require substantial adaptation for Asian contexts where emotional regulation represents normative social behavior rather than occupational burden.

Background: Weakness of the abdominal muscles reduces trunk control and impairs respiratory function in stroke patients. To strengthen the abdominal muscles, threshold expiratory muscle training and trunk FES can be used. Objectives: This study aimed to investigate whether a combined intervention of threshold expiratory muscle training and trunk FES is more effective in improving trunk control and respiratory function than threshold expiratory muscle training alone. Design: Randomized controlled trial. Methods: Thirty individuals with stroke were randomly assigned to either the experimental group (n=15) or the control group (n=15). The experimental group received threshold expiratory muscle training with trunk electrical stimulation, while the control group performed threshold expiratory muscle training only. Both groups underwent training three times per week for four weeks. Trunk control and respiratory function were assessed pre and post the intervention. Results: Both groups showed significant post-intervention improvement in respiratory function; however, the experimental group demonstrated a greater change than the control group. The control group showed significant improvement only in the total TIS score, whereas the experimental group showed significant improvement across all TIS subcomponents. Conclusion: Combining threshold expiratory muscle training with trunk FES is an effective approach for enhancing not only respiratory function but also trunk control. Synchronizing electrical stimulation with expiratory timing may increase efficiency and strengthen functional muscle contraction, suggesting meaningful clinical value.

목적: 본 연구는 2021년도 국민건강영양조사(KNHANES) 데이터를 활용하여 성인 당뇨병 환자의 안저검사 수검 및 당뇨망막병증 관련 요인을 파악하고자 하였다. 방법 : 본 연구는 2021년도 국민건강영양조사 원시자료를 이용한 단면 연구이다. 당뇨병을 진단받은 만 19세 이상 65세 미만 성인 257명의 자료를 포함하였다. 주요 변수는 성별, 연령, 교육수준, 소득수준, 당뇨병 치료, 공 복혈당, 당화혈색소(HbA1c), 최근 1년간 안저검사 수검 여부 및 당뇨망막병증 유병 여부였다. 자료 분석은 SPSS WIN 31.0을 이용하여 빈도분석, 카이제곱검정, 다변량 로지스틱 회귀분석을 수행하였다. 결과 : 안저검사 수검에 영향을 미친 요인은 성별로 확인되었으며, 여성은 남성보다 안저검사를 받을 가능성이 높았다(OR=1.99, 95% CI=1.10–3.59, p=0.023). 연령, 교육수준, 소득수준, 당화혈색소(HbA1c)는 안저검사 수 검 여부와 유의한 관련이 없었다. 반면, 당뇨망막병증 유병 여부는 교육수준과 당화혈색소(HbA1c)가 유의한 관련 요인이었다. 교육수준이 낮은 집단은 높은 집단에 비해 당뇨망막병증 발생 가능성이 유의하게 높았으며(OR=5.20, 95% CI=1.70–15.93, p=0.004), 당화혈색소(HbA1c)가 1% 증가할 때 당뇨망막병증 위험은 약 1.86배 증가하였 다(OR=1.86, 95% CI=1.32–2.61, p＜0.001). 성별, 연령, 소득수준은 유의한 요인이 아니었다. 결론 : 본 연구는 성인 당뇨병 환자에서 교육수준과 혈당조절 상태가 당뇨망막병증 발생의 중요한 요인임을 확 인하였다. 효과적인 합병증 예방을 위해서는 교육 취약계층을 중심으로 한 맞춤형 당뇨교육과 정기적 안저검사 참 여를 강화할 필요가 있다. 본 연구는 국가 단위 대표자료를 기반으로 당뇨 관련 시각 합병증 예방을 위한 공중보건 전략 마련에 기초자료를 제공한다.

기후변화에 따른 관리형 화분매개자 부족은 온실 딸기 재배에서 대체 화분매개자의 필요성을 높이고 있다. 재래꿀벌(Apis cerana)은 양봉꿀벌 (Apis mellifera)의 대체종으로 제안되었으나, 온실 조건에서의 직접 비교 연구는 제한적이다. 본 연구에서는 2024년 11월부터 2025년 3월까지 대 한민국 충남 논산의 딸기 온실에 두 종의 봉군을 설치하고, 봉군세력, 먹이활동, 화분매개 효율을 모니터링 하였다. 두 종 모두 세력이 감소했으나, 양봉꿀벌에서 감소 폭이 더 컸다. 종 간 먹이활동 차이는 정오 무렵에만 나타났으며, 세력으로 보정하면 사라졌다. 꽃 방문 및 정상 수과 형성률로 측정한 화분매개 효율은 종 간 유의한 차이가 없었으나, 방문당 효율은 양봉꿀벌에서 다소 낮은 경향을 보였다. 화분매개 효율은 먹이활동과는 양의 상관을, 봉군 세력과는 음의 상관을 나타냈다. 이러한 결과는 재래꿀벌이 겨울철 봉군세력을 더 안정적으로 유지하면서도 유사한 화분매개 서비스 를 제공함을 보여주며, 온실 딸기 재배에서 대체 화분매개자로서의 잠재성을 뒷받침한다.

This study quantitatively analyzed the ecological niche breadth (ENB) of 27 freshwater mollusk species (11,406 occurrence records) in Korea based on macroenvironmental gradients, including climate, topography, and land cover. We combined Levins’ index values (B: niche breadth, BA: equitability) with optimum-tolerance analysis (optimum value and tolerance range, t95-t05) to determine species-specific habitat strategies and environmental responses. The analysis revealed a distinct dichotomy in the habitat strategies of Korean freshwater mollusks, separating cold-water, lowdisturbance types in upstream areas from warm-water, disturbance-tolerant types in downstream areas, mainly structured by thermal and land-cover gradients. Species, such as Semisulcospira libertina, Radix auricularia, and the alien species Physa acuta, were identified as generalists, showing high B values but low BA values, suggesting that they are capable of inhabiting diverse environments but concentrate their presence in certain environmental conditions. Conversely, Koreoleptoxis nodifila and Clithon retropictum were classified as specialists with low B values and intermediate to high BA values, indicating stable and equitable distribution within restricted environmental limits. Urbanization appeared to be an influential limiting factor, showing low BA values for most species, whereas agricultural areas showed higher BA values, suggesting a comparatively broader habitat possibility. Notably, K. nodifila, a critically endangered and endemic species, showed optimal habitat conditions of low temperature (10.65°C), low urbanization (4.82%), and high forest cover (57.34%), confirming its status as a cold-water indicator species adapted to forested upstream systems. The study findings provide a quantitative framework to assess the environmental tolerance, vulnerability, and conservation priorities of Korean freshwater mollusks.

목적: 본 연구는 역동적 신체 활동 상황에서 HMD 기반 가상현실 기기 내부의 온·습도 및 열지수를 실시간 측정하 고, 이러한 환경 변화가 안구건조증과 시각적 불편감에 미치는 영향을 규명하는 데 목적이 있다. 이를 통해 활동형 VR 사용 시 안전성 확보와 열·습도 관리 기반의 최적화된 VR 환경 설계의 근거를 제시하고자 한다. 방법 : 체육계열 대학생 28명을 대상으로 수행되었으며, Oculus Quest2를 이용한 역동적 VR 복싱 콘텐츠 수 행 중 HMD 내부 온도·습도 및 열파지수를 Arduino–DHT11 기반 센서로 2.5초 간격으로 실시간 측정하였다. 참 가자는 안정 상태, 운동 상태, 회복 상태 각 15분씩 총 45분간 실험에 참여하였고, 심박수는 스마트밴드를 통해 목 표 운동 강도 범위(30~50% HRR)로 유지되었다. 안구건조증 평가는 실험 전·후 비침습적 눈물막 파괴시간(NI BUT), Schirmer 검사, OSDI 설문을 통해 객관·주관 지표를 모두 수집하였다. 통계 분석은 대응표본 t-검정과 카이제곱 검정을 사용하였으며 유의수준은 p>0.050로 설정하였다. 결과 : 연구 대상자(평균 23.44세)는 VR 사용 전후 NI BUT과 Schirmer 검사에서 유의한 변화가 나타나지 않았으나(p>0.050), OSDI 점수는 실험 후 유의하게 증가하여 주관적 안구 불편감이 상승한 것으로 확인되었다 (p>0.050). HMD 내부 환경 분석에서는 운동 직후 초기 구간(15~18분)에서 온도, 습도, 열지수의 변화율이 가 장 크게 증가하여(p<0.001) 역동적 신체 활동이 VR 장치 내부 미세환경에 즉각적이고 급격한 변화를 유발함을 보여주었다. 이후 구간에서는 환경 변화 속도가 완만해지며 점차 안정화되는 경향을 보였다. 종합하면, 단기간의 고강도 VR 사용은 내부 열·습도 환경의 급격한 변동과 더불어 사용자의 주관적 시각적 피로 증가와 관련됨을 시사한다. 결론 : 고강도 신체 활동 시 VR HMD 내부의 온·습도 및 열파지수는 급격히 상승하여 열적 불편감과 시각적 피로를 더욱 유발한다. 운동 종료 후에는 빠르게 회복되는 가역적 특성을 보였음으로 이러한 결과는 활동형 VR 사 용 시 휴식·환기 전략의 필요성과 안전성 기반의 HMD 설계 및 사용자 관리 지침 마련의 중요성을 제시한다.

목적 : 본 연구는 양안시기능 이상을 가진 아동을 대상으로 디지털 기반 시기능 훈련 프로그램의 훈련적 효과를 평가하는 것이다. 훈련 후 자각증상, 양안시 기능, 조절 및 융합여력, 안구운동성의 변화를 분석하고자 하였다. 방법 : 근거리 외사위 7Δ 이상 및 조절·융합 기능 저하를 보이는 아동 24명을 대상으로 굴절이상을 완전교정 후 디지털 시기능 훈련(총 2주, 주 3회, 회당 15분)을 실시하였다. 디지털 시기능 훈련은 디지털 폭주훈련(라이프 세이버카드), 디지털 주변월차트, 시선추적 기반 게이밍 시스템의 세 가지 모듈로 구성하였다. 훈련 전·후에 CISS 설문조사, 사위도(von-Graefe), PFV/NFV, NPA/NPC, 조절·버전스용이성, SCCO 검사, H-S scale, DEM 검 사, GST 검사를 3회 반복 측정하였다. 모든 수치는 Python 기반 통계 분석을 통해 p<0.050를 유의수준으로 검토 하였다. 결과 : 디지털 기반 시기능 훈련 후, 근거리 외사위도는 유의하게 감소하였으며 NPC 단축과 PFV 증가는 통계 적으로 유의한 개선을 보였다(p<0.050). 조절근점은 단축되고 폭주근점 또한 향상되어 조절 및 융합 능력의 기능 적 회복이 확인되었다. 조절·버전스 용이성에서는 조절용이성은 변화가 미약하였으나 버전스용이성은 유의한 증 가를 나타냈다. 안구운동성(SCCO, DEM, GST)은 전반적으로 개선되었으며 특히 DEM 검사에서 반응 시간이 유 의하게 단축되었다. CISS 총점은 모든 항목에서 감소하여 주관적 시각 증상이 뚜렷하게 경감되었다. 이러한 결과 는 디지털 기반 훈련이 기존 아날로그 시기능 훈련과 동등한 훈련 효과를 갖는다는 기존 연구와 일관된 패턴을 보 였다. 결론 : 디지털 기반 시기능훈련은 양안시기능, 조절력, 융합 버전스, 안구 운동성 및 주관적 증상의 전반에서 유 의한 향상을 보여 전통적 시기능 훈련과 동등한 훈련 효과를 확인하였다. 또한 게임화·시선추적 기반 UI는 훈련 참여도와 임상 적용 가능성을 확장하였다. 본 연구는 디지털 시기능 훈련이 아동의 폭주·조절 이상 개선에 효과적 인 훈련 옵션임을 시사한다.

심비디움 ‘연두랑’은 절화용으로 적합한 연녹색 품종을 개발 하기 위하여 2023년 국립원예특작과학원에서 육성한 신품종 으로 2009년에 C. ‘Daijeolturuk’과 C.‘Romeo’를 인공교배 하다. 교배 후 기내파종과 하우스 순화를 통해 121개의 실생묘 를 얻었고, 그 중 형태적, 생리적, 개화 특성을 포함한 종합적인 특성을 바탕으로 우수한 2계통을 1차 선발하였다. 이후 선발계 통의 안정성과 균일성을 확인하기 위하여 2016년부터 2022년 까지 특성검정을 수행하였고, 최종적으로‘C09037-45’한 계통 을 선발하였고 ‘원교 F1-80’로 계통명을 부여한 후,‘연두랑’으 로 명명하였다. 본 품종은 67.2 cm 길이의 직립성 화경에 약 22개의 연녹색 꽃을 착화하는 중형종으로, 절화수명은 평균 34.3일로, 대비품종 ‘러블리킹’보다 6일 이상 길었다.‘연두랑’ 은 1월부터 개화하며 기내 증식력은 대비 품종과 유사한 정도 로 나타나 상업적 활용을 위한 대량 증식이 가능할 것으로 판단 된다.

Background: Early recovery of cognitive function and lower-limb strength is critical for regaining mobility and independence after stroke. However, patients with cognitive impairment often have limited participation in conventional rehabilitation (CR). Objects: This study compared the effects of robotic tilt-table training (RT) group and CR group on cognitive function, lower-limb strength, balance, gait, and activities of daily living in patients with subacute stroke. Methods: In this retrospective study, 122 patients with subacute stroke were divided into two groups: the RT group and the CR group. The interventions were administered 5 times per week for a period of 4 weeks. Cognitive function was assessed using the Korean version of the Mini-Mental State Examination, muscle strength using Manual Muscle Test, spasticity using the Modified Ashworth Scale, balance using the Berg Balance Scale, gait using the Functional Ambulation Category, and activities of daily living using the Korean version of the Modified Barthel Index, both before and after the intervention. Data were analyzed using Wilcoxon signed-rank tests and Mann–Whitney U-tests. Between-group comparisons were performed on change scores (Δ = post − pre), and baseline differences were adjusted using ANCOVA or rank ANCOVA as appropriate (two-sided α = 0.05). Results: After 4 weeks of intervention, both groups showed within-group improvements in balance, gait, and activities of daily living (p < 0.05); however, the RT group demonstrated greater improvements in cognitive function and lower-limb muscle strength compared to the CR group. The two groups differed significantly in cognitive function and lower extremity muscle strength (p < 0.05) but not in spasticity, balance, gait, or activities of daily living (p > 0.05). Conclusion: RT may be effective in improving cognitive function and lower-limb strength in patients with subacute stroke, potentially serving as an adjunct rehabilitation strategy to promote early mobility and functional recovery. However, its effects on balance, gait, and spasticity were not significant, indicating the need for complementary task-specific training and further controlled studies.

우리나라 접목선인장 산업은 화훼 수출액의 43.9%를 차지하 며, 주로 비모란선인장(Gymnocalycium mihanovichii) 품종을 삼각주선인장(Selenicereus sp.) 대목에 접목하여 재배한다. 그 러나 농가에서 재배되는 접목선인장 비모란의 바이러스 감염률 이 80%에 달하고 있어 바이러스 검정을 통한 품종 개발과 보급 이 매우 중요하다. 2019년 분홍색 색상과 자구발생 특성이 우수 한 GG171077-32와 GG151099-28을 계통간 교배하여 2020 년 실생묘 15개체를 양성하여 기내 배양한 삼각주선인장에 접 목하였다. 그 중 분홍색의 색상과 자구 발생 특성이 우수하였던 4개체를 선발하여 2021년 1차 특성검정을 위한 계통으로 증식 하였다. 2021년 특성검정 계통 중 진분홍색을 띄며 자구 발생이 우수한 GG191177-7 계통을 선발하였다. 이후 2년간 농가 3개 소에서 실증시험을 병행하여 특성검정한 결과 GG191177-7 계통을 최종 선발하고 2024년 ‘핑크문’으로 명명하였다. 핑크 문’ 품종은 RHS Color Chart N66A의 진한 분홍색이며, 편원형으로 능수는 8.0개이고, 가시색은 갈색이며 길이는 3.8mm였 다. 모구의 구폭은 43.4mm였고 주당 평균 자구수는 18.4개였 다. 1차 선발 계통 37개체를 대상으로 real-time PCR을 이용 한 바이러스 검정 결과, cactus virus X (CVX)와 pitaya virus X (PiVX)의 단독 감염률은 각각 16.2%였고, CVX와 PiVX의 혼합 감염률은 32.4%였으며, 바이러스 미검출 개체의 비율은 35.1%였다. 바이러스 미검출 개체에서 생산된 자구를 증식하여 ‘핑크문’ 품종을 육성하였다.

Background: Muscle thickness (MT) measurement using ultrasound image is emerging as a useful method to assess muscle mass during stretching. Traditionally, range of motion (ROM) measurements assessed by digital inclinometer are considered reliable and valid parameter for monitoring muscle flexibility. The ultrasound-based measurement for MT to monitor muscle flexibility has yet to be validated. Objects: This study aimed to determine whether ultrasound measurement can serve as a valid alternative to a digital inclinometer for assessing muscle flexibility following stretching interventions. Methods: A randomized crossover design study was conducted with 20 healthy young participants. The stretching exercise program was carried out passive static and hold-relax proprioceptive neuromuscular facilitation stretching exercises applied on gastrocnemius-soleus muscle group with 3 times a week for 2 weeks. Data were collected 3 times for pre- and post-tests. Dorsiflexion ROM was measured by a digital inclinometer and the MT of gastrocnemius muscle by the ultrasound. Intraclass correlation coefficient (ICC) analysis for test-retest reliability, Wilcoxon sign rank test for stretching effects, and Spearman’s correlation analysis for determining the concurrent validity of two measurements. Results: ICC values of pre- and post-tests in both ROM and MT measurements were showed good to excellent intra rater reliabilities ranging from 0.782 to 0.968 (p < 0.001). A significant increase in the ROM measurements was observed following the stretching program (p < 0.01), whereas no significant change in the MT measurement was showed. Spearman’s correlations revealed weak relationships between the ROM and MT measurements (r = –0.217 for pre-test, r = –0.259 for post-test, r = –0.282, p < 0.05 for changes). Conclusion: These findings suggest that both the MT and ROM measurements were not compatible for monitoring muscle flexibility following stretching exercises regardless of their good reliabilities. Further investigations may be required to the MT measurement alone to be an alternative method.

Osteoprotegerin (OPG), a conventional potent inhibitor of osteoclastogenesis, is being increasingly recognized for its diverse roles beyond bone metabolism. However, the cell-autonomous role of OPG in regulating the differentiation and fate of mesenchymal progenitor cells (MPCs) remains to be fully elucidated. To address this issue, OPG-knockout (OPG-KO) human induced pluripotent stem cell-derived MPCs were generated using CRISPR/Cas9 technology. Transcriptomics revealed that OPG deficiency fundamentally alters the functional landscape of the MPCs, with a significant downregulation of the pathways related to the extracellular matrix (ECM), cell adhesion, and structural signaling. Specifically, the expression of numerous key ECM components was broadly attenuated in OPG-KO MPCs. Such molecular disruption functionally translated into severely impaired osteogenic potential, characterized by a marked transcriptional attenuation of osteogenic markers and reduced matrix mineralization at the cell level. Collectively, our findings demonstrate that OPG is essential for maintaining the structural integrity of the MPC niche by regulating the expression of ECM-related genes, thereby promoting osteoblast differentiation.

This study examined Korean university students’ ability to distinguish between authentic and modified spoken English texts and their perceptions of each in relation to language learning and content appeal. A total of 125 students completed a questionnaire after listening tasks, assessing their perceptions in three domains: authenticity versus modification, language learning, and content appeal. Questionnaire responses were analyzed using descriptive statistics and independent samples t-tests. The results indicated that participants could distinguish between the two types of texts. Modified texts were rated significantly higher for clarity and fluency, whereas authentic texts were viewed as more reflective of natural speech, including features such as unclear pronunciation and hesitation. Pronunciation clarity, however, was not perceived to significantly influence listening comprehension or difficulty. Participants evaluated modified texts more favorably for supporting language learning, particularly in pronunciation, listening skill development, and content understanding. Both text types were considered similarly effective for comprehending real-life conversations. Regarding content appeal, modified texts were rated as more engaging, though no significant differences emerged in their usefulness for real-life application or new information. These findings highlight the pedagogical importance of using both authentic and modified texts to address diverse learner needs.

This study investigates the effects of a college EFL reading course on learners’ language proficiency and critical thinking habits. Two cloze tests and the K Critical Disposition Test were administered to treatment and control groups at the beginning and end of the semester, and TOEIC scores were used to validate the proficiency measures. The treatment group also completed an end-of-semester questionnaire on perceived course impact. Both groups showed significant proficiency gains, but the treatment group did not show greater improvement than the control group. However, only the treatment group exhibited significant development in critical dispositions. A comparison of assessment results and self-reported perceptions suggests that learners’ judgments may not reliably reflect actual learning outcomes. These findings suggest that while deep reflection and discussion on English texts can enhance critical dispositions, achieving gains in proficiency and critical thinking simultaneously within a single course appears difficult. They also suggest the necessity of incorporating learning-based assessments into program evaluations to supplement subjective evaluations.

The lactic acid bacteria, Lactiplantibacillus plantarum KU15149 and Levilactobacillus brevis KU15176 were verified through phenotypic and genotypic analyses. Safety evaluation was conducted using multiple assays, including minimum inhibitory concentration assay for nine antibiotics, hemolytic activity, mucin degradation, gelatin liquefaction, urease activity, indole production, β-glucuronidase activity, bile salt deconjugation, cell cytotoxicity, D-/L-lactic acid production, and biogenic amine formation. Genotypically L. plantarum KU15149 and L. brevis KU15176 lacked all virulence and antibiotic resistance genes investigated. Consistent with these results, phenotypic assays showed that both strains were susceptible according to EFSA cut-off values and tested negative for hemolysis, mucin degradation, gelatin liquefaction, urease activity, indole production, β-glucuronidase activity, and bile salt deconjugation. Furthermore, neither strain showed cytotoxicity toward Caco-2 cells at a multiplicity of infection of 250. Production of D-lactic acid and biogenic amines was negligible in both bacteria. Overall, L. plantarum KU15149 and L. brevis KU15176 demonstrated safety and beneficial characteristics and therefore could serve as probiotic strains.

This study longitudinally examined how adolescents’ game use over time affects self-control, health status and health management, academic achievement, and family and peer relationships. To this end, we analyzed five-wave panel data from a national game user panel survey and sequentially applied latent growth models (LGMs), parallel-process LGMs, and time-varying covariate models. First, unconditional LGMs were estimated for eight variables—game use, self-control, health status, health management, academic achievement, parent–child communication, academic stress, and peer stress. The results showed that game use increased slightly but significantly over time, whereas self-control, health management behaviors, and academic achievement exhibited overall declining trajectories. Parent–child communication started at a relatively high level and showed no significant mean change, while academic and peer stress remained at relatively low levels with minimal mean-level fluctuation across waves. Because the mean of the linear slope factor was not significant for parent relationship, academic stress, or peer relationship, these variables were treated as comparatively stable contexts and excluded from subsequent models focusing on change dynamics. Next, we estimated conditional LGMs in which game use was included as a time-varying covariate in the growth models for self-control, health management, and academic achievement. Across all waves, higher game use was consistently associated with lower concurrent self-control, and with poorer health management and lower school grades at most time points. For health management, the negative association with game use was pronounced at the first three waves but its magnitude attenuated over time and became statistically nonsignificant at later waves. By contrast, academic achievement displayed a robust pattern of “increased game use → lower concurrent grades” at all five waves, indicating a stable negative association between frequent game use and short-term academic performance in adolescence. Finally, to investigate the long-term interrelations among game use, self-control, health management, and academic achievement, we estimated parallel-process LGMs. The results indicated that higher initial game use was associated with lower initial levels of self-control, health management, and academic achievement. Moreover, adolescents whose game use increased more rapidly over time showed steeper declines in self-control, greater deterioration in health management, and sharper drops in academic performance. A specific indirect pathway from initial game use to the slope of health management via the linear slope of self-control was statistically significant, suggesting that heavy game use can undermine health management behaviors partly by eroding self-regulation. In contrast, a mediation model specifying the slope of academic achievement as the final outcome did not converge, limiting interpretation of the game use–self-control–achievement pathway. Taken together, the findings demonstrate that the quantitative aspect of game use—how long adolescents play—has meaningful longitudinal implications for the developmental trajectories of self-control, health management, and academic achievement. At the same time, parent–child communication and academic and peer stress displayed relatively stable mean levels, implying that in this sample family and peer relationships functioned more as background contexts than as domains that deteriorate rapidly in tandem with game use. Rather than framing game use solely as a pathological disorder, the results underscore the importance of early monitoring of initial game-use levels and growth rates, as well as preventive interventions aimed at strengthening self-control and digital literacy, to protect adolescents’ health, learning, and family and peer relationships.