This studies were conducted to develop cultivation methods on three Asclepiadaceae fami-lies(Cynanchum wilfordii Hemsley, C. auriculatum Royle ex Wight and Metaplexis japonica Makino) ofwhich products are conventionally used as medicinal materials by analyzing plant growth. The variationof leaf weight of Asclepiadaceae families showed culmination point at August 15, and the stem showedhighest growth on August 30. The root weight increased linearly during the growth. The days for sprout-ing was most shortened in the Cynanchum wilfordii as 18 days, and C. auriculatum, Metaplexis japonicafollowed after. The seed harvesting dates was Oct. 8 in the Cynanchum wilfordii, Oct. 23 in the Metaplexisjaponica, and Nov. 1 in the C. auriculatum, respectively.