Site characterization for decommissioning Kori Unit 1 is ongoing in South Korea after 40 years of successful operation. Kori Unit 1’s containment building is assumed to be mostly radioactively contaminated, and therefore radiation exposure management and detailed contamination investigation are required for decommissioning and dismantling it safely. In this study, site-specific Derived Concentration Guideline Levels (DCGLs) were derived using the residual radioactivity risk evaluation tool, RESRAD-BUILD code. A conceptual model of containment building for Kori Unit 1 was set up and limited occupational worker building inspection scenario was applied. Depending on the source location, the maximum contribution source and exposure pathway of each radionuclide were analyzed. The contribution of radionuclides to dose and exposure pathways, by source location, is expected to serve as basic data in the assessment criteria of survey areas and classification of impact areas during further decommissioning and decontamination of sites.

The coat color of mammals is determined by the melanogenesis pathway, which is responsible for maintaining the balance between black-brown eumelanin and yellow-reddish pheomelanin. The melanogenesis-associated genes controlling pigmentation act as a complex and interact with each other to cause phenotypic and genotypic variations in cattle. That the MC1R genotype of Korean native cattle with dark muzzle was e/e or E+/e, while the genotype of Korean native cattle with light muzzle was E+/E+, which is a variant of the MC1R genotype in the Korean native cattle. Especially, the MC1R expression type is shows how much pigmentation, important factor in deciding its status in the coat and nose colours. However, information regarding the coat or nose colours-associated gene regulation of korean cattle is not yet unknown. Therefore, in this study was to investigate the expression patterns of melanogenesis-associated genes in black dot nose(korea brindle cattle) and normal nose(korea native cattle). Using microarray clustering and real-time polymerase chain reaction techniques, we analysed that the expression of genes involved in the mitogen-activated protein kinase (MAPK) and Wnt signaling pathways is distinctively regulated in the dark and light muzzle tissues. Differential expression of tyrosinase was also noticed, although the difference was not as distinct as those of MAPK and Wnt. We hypothesize that emphasis on the MAPK pathway in the Korea brindle cattle induces eumelanin synthesis through the activation of cAMP response elementbinding protein and tyrosinase, while activation of Wnt signaling counteracts this process and raises the amount of pheomelanin in the native cattle. Regarding the increasing interest in the genetic diversity of cattle stocks, genes we identified for differential expression in the brindle cattle vs. native cattle may serve as novel markers for genetic diversity among cows based on the coat and muzzle color phenotype.

Perturbation of normal behaviors (e.g., nursing and foraging) in honey bee colonies by any external factors would immediately reduce the colony’s capacity for brood rearing, which can eventually lead to collapse of entire colony. To investigate the effects of brood rearing suppression in the biology of honey bee workers (nurse and forager), the gene-set enrichment analysis (GSEA) was performed for the transcriptomes of worker bees with or without their brood rearing being suppressed, from which functional profiles of pathways under influences by each condition were identified. Blocking of normal labor (i.e., nursing or foraging) induced the over-representation of pathways related with reshaping of worker bee physiology, suggesting that transition of labor is physiologically reversible. In addition, brood rearing suppression appeared to result in the reduction of neuronal excitability and aggressiveness in both forager and nurse, which would be necessary to manage the in-hive stress under unfavorable conditions

Pheromone biosynthesis in the pheromone gland is stimulated by pheromone biosynthesis activating neuropeptide (PBAN) produced in the suboesophageal ganglion. PBAN binds its receptor and transduces biological signal into the molecules for the pheromone biosynthesis. To understand pheromone biosynthesis pathway in legume pod borer, Maruca vitrata, transcriptome of the pheromone gland was analyzed. A total of 191 contigs involved in the pheromone biosynthesis were identified. Putative pheromone biosynthetic pathways for sex pheromone components in M. vitrata were proposed through transcriptomic analysis.

Flexible production system has been expanded to all sectors of economy with the change of labor market and diversification of employment. The unstable employment with irregular work has replaced stable employment with regular work. This study has investigate the impact pathway of the type of employment on health status especially ill-health symptoms experiences. Among the first Korean Working Conditions Survey data, the employee's response data was used to analyze the path way with multiple regression analysis. The result has shown the direct effect of the type of employment on ill-health symptoms experience. Indirect effect of the type of employment was found the pathway via the exposure to noise, high temperature, low temperature, dust, skin contact to chemicals, painful posture, heavy material handling, standing position, repetitive movement of hands. However the exposure to the other hazardous factors such as organic solvent, wholebody vibration, radiation, lifting people, infectious materials were not influenced by the type of employment.

This study was conducted to find sensitive indicator of food intake and specific food group related to cognitive function and to analyze the pathway among factors affecting food intake and cognitive function of the aged. 179 people over 50 years old were investigated and all the data were analyzed by SPSS 10.0 package. Food frequency was more sensitive indicator to show the relationship between food intake and cognitive function of the aged than the numbers of standard amount of food eaten. Consumption of grains and starch, meat, fish, eggs and beans were strongly related to cognitive function of the aged and intake of vegetables and fruits also have relationship with it. Moreover, the more frequent eating the carbohydrate and the protein, the higher the cognitive level of the aged. Age, education period, income, blood pressure, duration after retirement, frequency of physical activity and BMI were correlated with food intake and cognitive function of the aged. Among them, age and frequency of physical activity were most strongly correlated with food intake, and education period with cognitive function of them. This investigation shows that more stable intake of carbohydrate and protein containing foods need to be supplied to low income aged and the importance of physical activity of the aged must be emphasized with food intake for better life of the aged.

수원과 수용가 간 연결성은 비정상상황 시 상수도관망의 기능 유지 정도를 나타내는 시스템 특성 중 하나이다. 상수도관망은 점과 선으로 구성된 그래프로 간략화 될 수 있기 때문에, 연결성 평가를 위해 주로 그래프 이론이 적용되었다. 하지만, 대부분의 연구는 상수도관망에 적합하지 않은 무 향-비가중 그래프 이론을 적용하였다. 본 연구에서는 유향-가중 그래프 이론을 상수도관망에 적용하였으며, 이를 기반으로 복잡한 수리해석 없이 상수도관망 연결성을 평가할 수 있는 지표인 SNSP (Source to Node Shortest Pathway)와 이의 역수인 SNSP-Degree (SNSP-D)를 제안하였다. 국내 J시 42개의 상수도관망을 이용하여 개발된 SNSP와 기존 상수도관망 성능평가지표 사이의 상관성 분석을 수행 및 검증하였다. 기존 상수도관 망 성능평가지표는 수리해석 결과를 지표 계산에 이용하는 3개의 회복력(Resilience) 지표와 에너지 효율 지표이다. 분석 결과, SNSP의 역수인 SNSP-D의 합과 기존 상수도관망 성능지표 사이에 평균적으로 0.87 이상의 높은 피어슨 상관계수(Pearson Correlation Coefficient, PCC) 값이 도출되었다. 특히, 회복력 지표 중 하나인 Modified Resilience Index (MRI)와 에너지 효율 지표의 경우 PCC 0.93 이상의 높은 상관관계를 가지는 것으로 나타났다. 또한 다중 회귀 분석을 통해 SNSP-D와 회복력 및 에너지 효율 간의 상관성에 영향을 미치는 수리학적 변인을 확인하였다. 본 연구에서 제안한 SNSP 지표가 상수도관망의 대략적인 회복력 및 에너지 효율 수준을 알려줄 수 있는 지표로 실무에서 널리 활용될 것으로 기대된다.