Licensees are required to protect critical digital assets (CDAs) in nuclear facilities against cyber-attacks, up to and including design basis threat (DBT), according to「ACT ON PHYSICAL PROTECTION AND RADIOLOGICAL EMERGENCY」. However, CDAs may be excluded from cyber security regulations at nuclear power plant decommissioning, and this may lead to severe consequences if the excluded CDAs contain sensitive information such as the number and location of nuclear fuels and information on security officers. In that case, that information could be leaked to the adversary without adequately removing the information before discarding the CDAs. It can be potentially abused to threaten nuclear facilities inducing radiological sabotage and nuclear material theft. So, controls of sensitive information are needed. This study aims to derive regulatory improvements related to discarding CDAs that have sensitive information by analyzing foreign cases such as IAEA and U.S. NRC. The sensitive information in the IAEA guide is the following: (1) details of physical protection systems and any other security measures in place for nuclear material, other radioactive material, associated facilities, and activities; (2) information relating to the quantity and form of nuclear material or other radioactive material in use or storage; (3) information relating to the quantity and form of nuclear material or other radioactive material in transport; (4) details of computer systems; (5) contingency and response plans for nuclear security events; (6) personal information; (7) threat assessments and security alerting information; (8) details of sensitive technology; (9) details of vulnerabilities or weaknesses that relate to the above topics; (10) historical information on any of the above topics. In the case of the U.S. NRC, they categorize sensitive information into three groups: (1) classified information, (2) safeguard information (SGI), (3) sensitive unclassified non-safeguards information (SUNSI). Classified information is information whose compromise would cause damage to national security or assist in manufacturing nuclear weapons. The SGI concerns the physical protection of operating power reactors, spent fuel shipments, strategic special nuclear material, or other radioactive material. Finally, SUNSI is generally not publicly available information such as personnel privacy, attorney-client privilege, and a confidential source. IAEA recommends protecting the above sensitive information in accordance with NSS No.23-G (Security of Nuclear Information), and NRC protects classified information, SGI, and SUNSI under relative laws. In the case of ROK, if security control measures are enhanced CDAs that possess sensitive information, the risk of information leakage will be decreased when those CDAs are discarded.
Nuclear Safety and Security Commission (NSSC) and KINAC review a Cyber Security Plan (CSP) by「ACT ON PHYSICAL PROTECTION AND RADIOLOGICAL EMERGENCY」. The CSP contains cyber security implementation plans for the licensee’s nuclear power plant, and it shall meet the requirements of KINAC/RS-015, a regulatory standard. The KINAC/RS-015 provides more detailed information on the legal requirements, so if licensees implement cyber security under the approved CSP, they can meet the law. To protect nuclear facilities from cyber-attacks, licensees should identify their essential digital assets, so-called “Critical Digital Assets” (CDAs). Then, they apply cyber security controls (countermeasures for cyber-attacks) on CDAs consisting of technical, operational, and management security controls. However, it is hard to apply cyber security controls on CDAs because of the large amounts of CDAs and security controls in contrast to the shortage of human resources. So, licensees in the USA developed a methodology to solve this problem and documented it by NEI 13-10, and US NRC endorsed this document. The main idea of this methodology is, by classifying CDAs according to their importance, applying small amounts of security controls on less important CDAs, so-called non-direct CDAs. In the case of non-direct CDAs, only basic cyber security controls are applied, that is, baseline cyber security controls. The baseline cyber security controls are a minimum set of cyber security controls; they consist of control a) from control g) a total of 7 controls. Although non-direct CDAs are less critical than other CDAs (direct CDAs), they are still essential to protect them from cyber-attacks. This paper aims to suggest a cyber security enhancement method for non-direct CDAs by analyzing the baseline cyber security controls. In this paper, baseline cyber security controls were analyzed respectively and relatively and then concluded how to apply small amounts of cyber security controls on non-direct CDAs rather than direct CDAs without scarifying cyber security.
Diabetic encephalopathy is a major complication with cognitive impairment and neurodegeneration in patients with type 1 or type 2 diabetes mellitus (DM). DM-induced glucolipotoxicity is a risk factor for Alzheimer’s disease–like phenotype, including amyloidogenesis, tau hyperphosphorylation, and neuronal apoptosis. Although the detailed mechanism underlying the pathogenesis of diabetic encephalopathy remains unclear, mitochondrial oxidative stress is emerging as a key factor for diabetic complications and neurodegeneration. A deeper understanding of the regulatory mechanism of mitochondrial oxidative stress under hyperglycemic conditions will provide insights into the development of therapeutic strategies for diabetic encephalopathy. Here, we review the role of mitochondrial oxidative stress in diabetic encephalopathy and the regulatory mechanisms by which high glucose induces the generation of mitochondrial reactive species oxygen species in neuronal cells. This review also summarizes the mitochondrial-dependent and -independent pathways (O-linked-N-acetylglucosaminylation, calcium, and glycogen synthase kinase 3β signaling) that regulate mitochondrial oxidative stress in a DM model.
Oilseed rape is known to crop having low nitrogen use efficiency (NUE) but requires high levels of N fertilizer. NUE is associated with N remobilization from source to sink organ, consequently affects seed yield. Remobilization of leaf N is also related to transport of C/N metabolites in phloem. However, interaction between seed yield and phloem transport was not fully documented. In response to seed yield, N and C metabolites and their transport into seed from bolting to pod filling stage investigated in two contrasting genotypes (Capitol and Pollen) cultivated under ample (HN) or limiting nitrate (LN) supply. Seed yield was significantly reduced in N limitation and its reduction rate was much lower in Capitol than in Pollen compared to HN treated plants. Amino acid and protein content was higher in Capitol than in Pollen at bolting stage. They gradually decreased during plant development but not significant between two cultivars and/or two treatments. Glucose, fructose and sucrose content were 1.8-,1.6- or 1.25-fold higher in LN condition than in HN condition, respectively. Amino acid and sucrose content in phloem were largely higher in Capitol than in Pollen under LN condition. These results indicate that the higher seed yield might be related to greater transport ability of amino acid and sucrose in phloem under LN condition.
To investigate the impact of nitrogen (N) mineral on reproductive potential of Brassica napus L, plants were treated with different levels of N treatment (N0; N100; N500). The half of N content for each treatment were applied at the beginning of the early vegetative stage and the rest was applied at the late vegetative stage. Nitrogen content in plant tissues such as root, stem and branch, leaf, pod and seed was analyzed and harvest index (HI) was calculated as percentage of seed yield to total plant weight. Biomass and nitrogen content were significantly affected by different levels of N supply. Biomass was significantly decreased by 59.2% in nitrogen deficiency (N0) but significantly increased by 50.3% in N excess (N500), compared to control (N100). Nitrogen content in all organs was remarkably increased with nitrogen levels. N distribution to stem and branches, and dead leaves was higher in N-deficient (N0) and N excessive plants (N500) than in control (N100). However, nitrogen allocated to seed was higher in control (N100) than in other treatments (N0 or N500), accompanied by higher HI. These results indicate that the optimum level of N supply (N100) improve HI and N distribution to seed and excessive N input is unnecessary.
This study was carried out to explore possibilities of cultivating horticultural crops in the air-dome greenhouse in comparison to the common iron-frame greenhouse as the standard. The levels of carbon dioxide and atmospheric pressure measured inside the air-dome greenhouse turned out to be higher than those measured inside the iron-frame greenhouse. Contrastingly, light intensity was relatively weaker inside the air-dome greenhouse due to the air-inflated double layers. Plants of melon and cherry tomato were cultivated from May 2 to August 12, 2016, respectively in the two greenhouses. For melon plants, growth in the air-dome greenhouse effectively increased fruit weight as well as trunk circumference compared to iron-frame greenhouse. Moreover, soluble sugar content of melon fruit was significantly higher when cultivated in the air-dome greenhouse. For cherry tomato plants, fruit yield of cherry tomato was significantly increased inside the air-dome greenhouse. Furthermore, it has been found that the air-dome greenhouse was considerably effective in shortening the growing period of melon and cherry tomato plants in comparison to the iron-frame greenhouse.
Rice stem borer, Chilo suppressalis Walker is a significant rice insect pest. A newly hatched larva bores a hole into the rice stem and feeding inside. The damage results in drying and white heads of rice. Climate change will affect pest and its host population dynamics variously. In this study, the degree of asynchrony between emergence of rice stem borer and rice transplanting was examined by their phenology models. Also, correlation was examined between winter mortalities of the rice stem borer and relative humidity categorized by daily minimum temperature in 12 sites throughout the country from 1992 to 2013. The degree of asynchrony appears to be increased in future climate condition. And we found a negative correlation between winter mortality and the relative humidity. Winter mortality will be decreased in the future because of increasing winter minimum temperature and snowfall. We hypothesize that the stem borer may increasingly harbor in alternative hosts such as reed in its first generation and move to rice in the second generation. Currently the simulation study is being conducted to verify this hypothesis.
Using whole cell current- and voltage-clamp recording we investigated the characteristics and pharmacology of group I metabotropic glutamate receptor (mGluR)-mediated responses in rat medial vestibular nucleus (MVN) neurons. In current clamp conditions, activation of mGluR I by application of the group I mGluR agonist (R,S)-3,5-dihydroxyphenylglycine (DHPG) induced a direct excitation of MVN neurons that is characterized by depolarization and increased spontaneous firing frequency. To identify which of mGluR subtypes are responsible for the various actions of DHPG in MVN, we used two subtype-selective antagonists. (S)-(+)- alpha-amino-a-methylbenzeneacetic acid (LY367385) is a potent competitive antagonist that is selective for mGluR1, whereas 2-methyl-6-(phenylethynyl)-pyridine (MPEP) is a potent noncompetitive antagonist that is selective for mGluR5. In voltage clamp conditions, DHPG application increased the frequency of spontaneous and miniature inhibitory postsynaptic currents (IPSCs) but had no effect on amplitude distributions. Antagonism of the DHPG-induced increase of miniature IPSCs required the blockade of both mGluR1 and mGluR5. DHPG application induced an inward current, which can be enhanced under depolarized conditions. DHPG-induced current was blocked by LY367385, but not by MPEP. Both LY367385 and MPEP antagonized the DHPG-induced suppression of the calcium activated potassium current (IAHP). These data suggest that mGluR1 and mGluR5 have similar roles in the regulation of the excitability of MVN neurons, and show a little distinct. Furthermore, mGluR I, via pre- and postsynaptic actions, have the potential to modulate the functions of the MVN.
비압축성 물체률 위한 일반적인 유한요소 공식화는 혼히 사용되는 사각형요소에서조차 압력해의 진동화
(oscillations ) 또는 pressure ~es 현상융 나타낸다. 압력해의 안정화률 위한 규준은 소위 BabuSka-Brezzi
안정조건이며, 위의 요소들은 이 조건율 만족시키지 못한다. 본 연구에서는 선형변위해와 상수값의 압력해률
갖는 사각형요소 사용시 압력해률 안정화시키기 위해 요소의 변에서 발생하는 불연속압에 근거한 압력연속여
분치률 사용한다. 이 압력여분치률 비압축성 탄성론으로부터 유도되는 QIPO요소에 적용하며 매개변수의 변
화에 따른 수치혜의 안정화의 정도률 연구한다. 압력해는 압력 여분치 사용시 안정화될 수 있으며, 혜의 안정
화는매개변수에 민감성을나타내었다.
1998년 6월부터 9월까지 4개월간 수초자생 논에서 서식하는 말라리아 매개모기(Anopheles sinensis)를 대상으로 포식천적 송사리(Aplocheilus latipes)와 식식성 어류(Tilapia mossambicus niloticus)의 병합적 처리에 의한 생물학적 방제효과를 경기도 수원소재 대학 부속농장 실험포장에서 야외 조사하였다. 포식천적어 송사리는 논 수면에 방사율로, 식식성 어류 Ti-lapia는 비율로 병합적 처리한 결과, 처리 일주일후에 말라리아 매개모기는 대조군에 비해 70.8%의 방제효과를 나타내었고 4주와 5주후에 방제율은 점차 증가하여 각각 73.5%와 80.2%에 달하였으며, 5주후에는 말라리아 매개모기와 집모기(Culex pipiens)를 합하여 80~82%의 모기개체군 밀도의 억제효과를 계속 유지하였다. 송사리만의 비율로 단일처리한 논에서는, 4주후 말라리아 매개모기의 방제효과는 평균 51.4~56.5%로 비교적 저조하게 나타났으며, 모기 유충의 개체군 밀도를 억제하기 위한 미생물제제 B.t.i.(R153.78)을 1 kg/ha의 농도로 병합처리하여 그 방제효과를 비교 고찰하였다.
We screened the drought tolerant maize using seventeen maize genotypes from different sources, nine inbred genotypes from United States Department of Agriculture (USDA) (B73, CML103, CML228, CML277, CML322, CML69, Ki3, Ki11, and NC350), three Southeast Asian genotypes (DK9955, LVN-4, and 333), and five Korean hybrids (Cheongdaok, Gangdaok, Ilmichal, Kwangpyeongok, and Pyeonganok). We evaluated anthesis-silking interval (ASI), leaf senescence (LS), ears per plant (EPP), tassel length (TL), and fresh weight (FW) at silking date. According to ASI and LS examination, CML103 and Kill were drought tolerant genotypes, wheareas Ki3 and 333 were drought susceptible. EPP, TL, and FW differed according to drought resistance. Grain yield was correlated strongly with ASI, but moderately with LS. Difference in ASI between drought-stressed (DS) and well-watered (WW) conditions was less than three days in CML228, CML103, Cheongdaok, NC350, B73, Ki11, CML322, and Kwangpyeongok, whereas that of Ki3, Pyeonganok, and Gangdaok was more than 6.5 days. We concluded that CML228, CML103, Cheongdaok, NC350, B73, Ki11, CML322, and Kwangpyeongok are drought tolerant genotypes, whereas Ki3, Pyeonganok, and Gangdaok are drought susceptible.
Arabidopsis atDjC53 and atDjC32 gene DnaJ-like protein homologous to DnaJ-like protein was characterized for the functional analysis of DnaJ-like protein. It was shown that atDjC53 and atDjC32 RNA expression is induced by heat shock stress and atDjC53- and atDjC32-GFP was targeted to the nucleus of protoplasts. The atDjC53 and atDjC32 promoter (1 kb) was isolated and fused to the GUS reporter gene to investigate gene regulation of atDjC53 and atDjC32 specific to heat shock stress or to developmental organ in the transgenic lines. RNAi and overexpression construct was employed to generate atDjC53 and atDjC32 knock-out plants for the study of their function. Molecular function of atDjC53 and atDjC32 is discussed in relation to heat shock and also developmental stages in Arabidopsis.